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Questions and Answers
What is the drug class of Didanosine?
What is the drug class of Didanosine?
- Non-nucleoside RTI
- Integrase Inhibitor
- Nucleoside RTI (adenosine analogue) (correct)
- Protease Inhibitor
What are the brand names and abbreviations for Didanosine?
What are the brand names and abbreviations for Didanosine?
Videx, Videx EC, ddI
What are the major adverse drug reactions (ADRs) of Didanosine?
What are the major adverse drug reactions (ADRs) of Didanosine?
Diarrhea, Peripheral neuropathy, Pancreatitis
Didanosine has major interactions with other drugs.
Didanosine has major interactions with other drugs.
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What are the dosing considerations for Didanosine?
What are the dosing considerations for Didanosine?
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Study Notes
Didanosine Overview
- Didanosine is classified as a nucleoside reverse transcriptase inhibitor (RTI) and is an adenosine analogue.
- Its brand names include Videx and Videx EC, with the abbreviation ddI commonly used.
Major Adverse Drug Reactions (ADRs)
- Diarrhea is a notable side effect, often due to the buffer used in tablets and powder formulations.
- Peripheral neuropathy is another significant ADR associated with didanosine.
- Pancreatitis presents a serious potential risk when using this medication.
Drug Interactions
- Didanosine has no major known drug interactions, making it relatively safe in terms of compatibility with other medications.
Dosing Considerations
- Once daily (QD) dosing is feasible with the enteric-coated formulation.
- For optimal effectiveness, didanosine should be taken on an empty stomach, enhancing absorption.
- Renal function adjustments in dosing are recommended to ensure safety and efficacy in patients with compromised kidney function.
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Description
Test your knowledge about Didanosine, an important nucleoside reverse transcriptase inhibitor used in HIV treatment. This quiz covers its drug class, brand names, major adverse drug reactions (ADRs), interactions, and dosing information. Perfect for pharmacy students and healthcare professionals!
