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Diagnosis of Toxoplasmosis: Microbiologic Tests and Clinical Abnormalities
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Diagnosis of Toxoplasmosis: Microbiologic Tests and Clinical Abnormalities

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Questions and Answers

What clinical abnormalities are specific to toxoplasmosis?

  • Neutrophilic leukocytosis
  • Eosinophilia (correct)
  • Monocytosis
  • Lymphocytosis
  • Which of the following is NOT an abnormality found in the cerebrospinal fluid of cats with acute CNS toxoplasmosis?

  • Increased neutrophils
  • Small mononuclear cells
  • Mixed inflammatory cell infiltrates
  • High lymphocyte count (correct)
  • What is a distinctive characteristic of hyperglobulinemia in dogs with chronic toxoplasmosis?

  • It is generally polyclonal (correct)
  • It is associated with neutrophilic leukocytosis
  • It is monoclonal
  • It is caused by low protein levels
  • Which of the following can be detected in the urine of some dogs or cats with clinical toxoplasmosis?

    <p>Proteinuria</p> Signup and view all the answers

    What is the estimated prevalence of feline chronic gingivostomatitis complex in first opinion practice in the United Kingdom?

    <p>0.7%</p> Signup and view all the answers

    What percentage of cats with chronic oral disease have been found to shed FCV in various studies?

    <p>More than 80%</p> Signup and view all the answers

    What has recent work shown about the correlation between FCV load and disease severity or outcome?

    <p>No correlation</p> Signup and view all the answers

    What is the primary site for viral replication in FCV infection?

    <p>Oral and respiratory tissues</p> Signup and view all the answers

    Which type of cells are primarily infected by FCV in the lower respiratory complications?

    <p>Type II pneumocytes</p> Signup and view all the answers

    What is the most prominent pathologic feature of FCV infection?

    <p>Vesicle formation</p> Signup and view all the answers

    In FCV infection, what has been overemphasized in the past due to experimental studies using aerosol challenge?

    <p>Primary interstitial pneumonia</p> Signup and view all the answers

    What is a common clinical sign present in most strains of FCV?

    <p>Ocular and nasal discharges</p> Signup and view all the answers

    Which organ is NOT commonly affected by lesions associated with FCV infection?

    <p>Kidney</p> Signup and view all the answers

    What is a distinguishing feature of FCV-Associated Virulent Systemic Disease (VSD)?

    <p>Presence of oral ulceration</p> Signup and view all the answers

    Which symptom is NOT typically associated with FCV infection?

    <p>Lameness without pyrexia</p> Signup and view all the answers

    What is a potential complication associated with some strains of FCV?

    <p>Lameness after vaccination</p> Signup and view all the answers

    What is a characteristic feature of FCV-VSD outbreaks?

    <p>Nosocomial infections</p> Signup and view all the answers

    Which of these organs is not commonly associated with viral antigen detection in FCV-infected cats?

    <p>Brain</p> Signup and view all the answers

    What sets apart strains of FCV from each other?

    <p>'Tropism' and 'virulence'</p> Signup and view all the answers

    What is a distinct feature of FCV-induced acute synovitis?

    <p>'Oral' ulceration</p> Signup and view all the answers

    The virulence of FCV can result in which of the following?

    <p>Fatal pneumonia</p> Signup and view all the answers

    What has recent research shown about the correlation between FCV load and disease severity or outcome?

    <p>There is no correlation between FCV load and disease severity or outcome.</p> Signup and view all the answers

    What percentage of cats with chronic oral disease have been found to shed FCV in studies?

    <p>Over 90%</p> Signup and view all the answers

    Which agent, besides FCV, is likely to be involved in feline chronic gingivostomatitis complex according to the text?

    <p>Feline Immunodeficiency Virus (FIV)</p> Signup and view all the answers

    Which type of cells have been found to be infected by FCV in alveolar macrophages and to a lesser extent, type II pneumocytes?

    <p>Activated alveolar macrophages</p> Signup and view all the answers

    What has recent research suggested about the occurrence of primary interstitial pneumonia in FCV infection?

    <p>It has been overemphasized due to aerosol challenge studies</p> Signup and view all the answers

    What is the main pathologic feature that distinguishes FCV infection?

    <p>Necrosis of overlying epithelium</p> Signup and view all the answers

    Which tissues may FCV be found in, besides oral and respiratory tissues?

    <p>Synovial fluid</p> Signup and view all the answers

    What are the common lesions seen in FCV-infected joints?

    <p>Acute synovitis, thickening of synovial membrane, and increased amount of synovial fluid</p> Signup and view all the answers

    Which type of lesions are widespread in cases of FCV-associated virulent systemic disease (VSD)?

    <p>Oral ulceration and subcutaneous edema</p> Signup and view all the answers

    Where have viral antigens been detected in FCV infection?

    <p>Skin and nasal mucosa</p> Signup and view all the answers

    Which of the following is a characteristic sign of FCV infection?

    <p>Facial edema</p> Signup and view all the answers

    In FCV infection, what is a common early sign apart from pyrexia?

    <p>Ulceration on tongue</p> Signup and view all the answers

    What is a distinguishing feature of some strains of FCV?

    <p>Characterized by enteritis</p> Signup and view all the answers

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