Diagnosis of Hypothyroidism in Animals

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Questions and Answers

What is the most commonly performed static thyroid hormone measurement for screening hypothyroidism in dogs?

  • Free T4 concentration by analogue methods
  • Free T4 concentration by direct dialysis
  • Total T4 concentration (correct)
  • Total T3 concentration

Which serum biochemical abnormality is widely observed in dogs with hypothyroidism?

  • High serum triglycerides
  • Low serum cholesterol
  • Hypercholesterolemia (correct)
  • Normal alkaline phosphatase levels

What is the classic hematologic finding associated with hypothyroidism in dogs?

  • Normocytic, normochromic, regenerative anemia
  • Normocytic, normochromic, nonregenerative anemia (correct)
  • Macrocytic, hyperchromic, regenerative anemia
  • Microcytic, hypochromic, nonregenerative anemia

Why is measurement of free T4 not always superior to total T4 in diagnosing hypothyroidism in dogs?

<p>Differences in serum binding proteins affect free T4 assays (B)</p> Signup and view all the answers

What should be suspected when serum T3 concentrations are high in dogs with documented hypothyroidism?

<p>Anti-T3 antibodies interference (C)</p> Signup and view all the answers

Why is the diagnostic value of serum T3 determination considered weak during early thyroid failure?

<p>The thyroid increases relative T4 synthesis during failure (B)</p> Signup and view all the answers

What is the most reliable method for diagnosing hypothyroidism in dogs?

<p>Measuring serum thyroid hormone levels (C)</p> Signup and view all the answers

Which statement about hypothyroidism in dogs is true?

<p>It is probably one of the most overdiagnosed diseases in dogs (C)</p> Signup and view all the answers

What can lead to low serum thyroid hormone measurements in euthyroid (normal thyroid function) dogs?

<p>Nonthyroidal illness and prior administration of certain drugs (C)</p> Signup and view all the answers

What is the purpose of provocative thyroid function tests in diagnosing hypothyroidism?

<p>To confirm the diagnosis by stimulating the thyroid gland (A)</p> Signup and view all the answers

What is the primary factor in choosing and interpreting diagnostic tests for hypothyroidism?

<p>The index of suspicion for hypothyroidism (C)</p> Signup and view all the answers

What does the text suggest about clinicopathologic abnormalities associated with hypothyroidism?

<p>The severity usually correlates with the severity and chronicity of the hypothyroid state (A)</p> Signup and view all the answers

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