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Diagnosis of Hypothyroidism in Animals

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Questions and Answers

What is the most commonly performed static thyroid hormone measurement for screening hypothyroidism in dogs?

Free T4 concentration by analogue methods

Free T4 concentration by direct dialysis

Total T4 concentration (correct)

Total T3 concentration

Which serum biochemical abnormality is widely observed in dogs with hypothyroidism?

High serum triglycerides

Low serum cholesterol

Hypercholesterolemia (correct)

Normal alkaline phosphatase levels

What is the classic hematologic finding associated with hypothyroidism in dogs?

Normocytic, normochromic, regenerative anemia

Normocytic, normochromic, nonregenerative anemia (correct)

Macrocytic, hyperchromic, regenerative anemia

Microcytic, hypochromic, nonregenerative anemia

Why is measurement of free T4 not always superior to total T4 in diagnosing hypothyroidism in dogs?

Differences in serum binding proteins affect free T4 assays Signup and view all the answers

What should be suspected when serum T3 concentrations are high in dogs with documented hypothyroidism?

Anti-T3 antibodies interference Signup and view all the answers

Why is the diagnostic value of serum T3 determination considered weak during early thyroid failure?

The thyroid increases relative T4 synthesis during failure Signup and view all the answers

What is the most reliable method for diagnosing hypothyroidism in dogs?

Measuring serum thyroid hormone levels Signup and view all the answers

Which statement about hypothyroidism in dogs is true?

It is probably one of the most overdiagnosed diseases in dogs Signup and view all the answers

What can lead to low serum thyroid hormone measurements in euthyroid (normal thyroid function) dogs?

Nonthyroidal illness and prior administration of certain drugs Signup and view all the answers

What is the purpose of provocative thyroid function tests in diagnosing hypothyroidism?

To confirm the diagnosis by stimulating the thyroid gland Signup and view all the answers

What is the primary factor in choosing and interpreting diagnostic tests for hypothyroidism?

The index of suspicion for hypothyroidism Signup and view all the answers

What does the text suggest about clinicopathologic abnormalities associated with hypothyroidism?

The severity usually correlates with the severity and chronicity of the hypothyroid state Signup and view all the answers