Practice Bulletin 128: Diagnosis of Abnormal Uterine Bleeding
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Questions and Answers

What percentage of outpatient visits to the gynecologist are attributed to abnormal uterine bleeding?

  • 70%
  • 10%
  • 33% (correct)
  • 50%
  • What is the normal duration of menstrual flow?

  • 5 days (correct)
  • 3 days
  • 10 days
  • 7 days
  • Which of the following is NOT part of the PALM–COEIN classification system?

  • Malignancy
  • Oligomenorrhea
  • Coagulopathy
  • Menorrhagia (correct)
  • How long does a normal menstrual cycle typically last?

    <p>21 to 35 days</p> Signup and view all the answers

    What type of bleeding does the document explicitly state it does NOT address?

    <p>Pregnancy-related bleeding</p> Signup and view all the answers

    What term is used to describe heavy menstrual bleeding?

    <p>Menorrhagia</p> Signup and view all the answers

    Which organization developed the PALM–COEIN nomenclature system?

    <p>The International Federation of Gynecology and Obstetrics</p> Signup and view all the answers

    What is a known cause of abnormal uterine bleeding?

    <p>Hormonal imbalances</p> Signup and view all the answers

    What classification system is used for understanding the causes of abnormal uterine bleeding (AUB)?

    <p>PALM-COEIN</p> Signup and view all the answers

    Which of the following is not a structural cause of abnormal uterine bleeding according to the PALM-COEIN classification?

    <p>Coagulopathy (AUB-C)</p> Signup and view all the answers

    What does the 'P' in the PALM-COEIN classification stand for?

    <p>Polyp</p> Signup and view all the answers

    Which of the following is classified under nonstructural causes of abnormal uterine bleeding?

    <p>Endometrial (AUB-E)</p> Signup and view all the answers

    What is a recommended method for evaluating abnormal uterine bleeding?

    <p>Thorough medical history and physical examination</p> Signup and view all the answers

    Which of the following conditions is specifically linked to ovulatory dysfunction in the COEIN classification?

    <p>Ovulatory dysfunction (AUB-O)</p> Signup and view all the answers

    What should be considered during the evaluation of women with abnormal uterine bleeding regarding their demographic factor?

    <p>Age-related factors</p> Signup and view all the answers

    What is the classification for bleeding that occurs between menstrual periods?

    <p>Intermenstrual bleeding (IMB)</p> Signup and view all the answers

    What imaging method is recommended when there is a risk of structural anomaly and previous medical therapy has been unsuccessful?

    <p>Magnetic Resonance Imaging (MRI)</p> Signup and view all the answers

    Which condition would warrant an endometrial biopsy based on risk factors?

    <p>Chronic ovulatory disorder</p> Signup and view all the answers

    If ultrasound indicates a normal endometrial cavity, what further evaluation is typically unnecessary?

    <p>Endometrial biopsy</p> Signup and view all the answers

    In which scenario would MRI be particularly valuable for evaluation?

    <p>In virginal girls and women where other methods are not feasible</p> Signup and view all the answers

    What does AUB-M refer to in the context of uterine evaluation?

    <p>Malignancy and hyperplasia</p> Signup and view all the answers

    When is endometrial biopsy deemed appropriate?

    <p>For patients with atypical hyperplasia</p> Signup and view all the answers

    What is a reason that may complicate evaluation by hysteroscopy?

    <p>Inconclusive results from previous assessments</p> Signup and view all the answers

    Which of the following is NOT a type of abnormal uterine bleeding indicated by the abbreviation AUB?

    <p>AUB-L (lesion)</p> Signup and view all the answers

    What is one of the imaging techniques compared with sonohysterography for detecting intracavitary pathologies?

    <p>MRI</p> Signup and view all the answers

    Which comparison was made regarding the effectiveness in women with abnormal uterine bleeding?

    <p>Hydrosonography vs. transvaginal ultrasonography</p> Signup and view all the answers

    What is the primary topic of comparison in the studies mentioned in the content?

    <p>Imaging techniques for uterine evaluations</p> Signup and view all the answers

    Which study level was assigned to the comparison of transvaginal sonography and saline infusion sonography?

    <p>Level II-3</p> Signup and view all the answers

    In the context of imaging techniques for uterine evaluation, what does 'intracavitary pathologies' refer to?

    <p>Conditions or growths within the uterine cavity</p> Signup and view all the answers

    What advantage does 3D saline infusion sonography have over 2D saline infusion sonography?

    <p>Increased accuracy in detecting fibroids</p> Signup and view all the answers

    Which imaging modality was discussed for evaluating fibroid burden in women?

    <p>Magnetic resonance imaging</p> Signup and view all the answers

    Which imaging method is described as having a clinical value in diagnosing abnormal uterine bleeding?

    <p>Saline infusion sonography</p> Signup and view all the answers

    Which condition is classified under the PALM-COEIN system as endometrial hyperplasia or carcinoma?

    <p>AUB-M</p> Signup and view all the answers

    What is the primary pathological mechanism in ovulatory AUB?

    <p>Unopposed estrogen</p> Signup and view all the answers

    Which of the following is an inherited coagulopathy that can contribute to abnormal uterine bleeding?

    <p>Von Willebrand disease</p> Signup and view all the answers

    What percentage of women presenting with heavy menstrual bleeding may have an underlying bleeding disorder?

    <p>20%</p> Signup and view all the answers

    Which diagnostic screening should be performed if there is concern about a bleeding disorder related to AUB?

    <p>Hemostasis evaluation</p> Signup and view all the answers

    Which of the following disorders is categorized under ovulatory dysfunction causing AUB?

    <p>Polycystic ovary syndrome (PCOS)</p> Signup and view all the answers

    Which class of medications is known to potentially cause AUB?

    <p>Nonsteroidal anti-inflammatory drugs (NSAIDs)</p> Signup and view all the answers

    Which statement about ovulatory AUB is accurate?

    <p>It includes a spectrum of disorders from amenorrhea to irregular heavy periods.</p> Signup and view all the answers

    Study Notes

    Abnormal Uterine Bleeding (AUB) Overview

    • AUB defined as menstrual flow that deviates from normal volume, duration, regularity, or frequency.
    • One-third of gynecologist outpatient visits are for AUB; it constitutes over 70% of gynecologic consultations in perimenopausal and postmenopausal women.

    Classification of AUB

    • A new classification system, PALM–COEIN, categorizes AUB into structural and nonstructural causes.
    • Structural causes (PALM):
      • Polyp (AUB-P)
      • Adenomyosis (AUB-A)
      • Leiomyoma (AUB-L)
      • Malignancy & hyperplasia (AUB-M)
    • Nonstructural causes (COEIN):
      • Coagulopathy (AUB-C)
      • Ovulatory dysfunction (AUB-O)
      • Endometrial (AUB-E)
      • Iatrogenic (AUB-I)
      • Not yet classified (AUB-N)

    Normal Menstrual Cycle Parameters

    • Normal menstrual flow typically lasts 5 days.
    • Menstrual cycles range from 21 to 35 days.

    Evaluation of AUB

    • Comprehensive evaluation includes medical history, physical examination, and diagnostic tests.
    • Key elements of medical history:
      • Patterns and severity of menstrual bleeding.
      • Pain associated with bleeding.
      • Family history of AUB or bleeding disorders.
    • Conditions like von Willebrand disease and PCOS must be considered.

    Diagnostic Procedures

    • Initial screening for underlying bleeding disorders is critical for women with heavy menstrual bleeding.
    • Imaging studies:
      • Transvaginal ultrasound is often the first line for imaging.
      • Hysteroscopy and sonohysterography may be necessary for further evaluation.

    Management Guidelines

    • Risk factors for endometrial hyperplasia or malignancy dictate the necessity of endometrial biopsy.
    • Women at higher risk should undergo appropriate imaging assessments (e.g., MRI if required).
    • Management tailored based on the classification of AUB and individual patient factors.

    Pathophysiology of AUB

    • Common causes of AUB include:
      • Endometrial polyps (AUB-P)
      • Adenomyosis (AUB-A)
      • Uterine leiomyomas (AUB-L)
      • Endometrial hyperplasia or carcinoma (AUB-M)
    • Ovulatory dysfunction (AUB-O) linked to hormonal imbalances, often due to endocrine disorders.

    Clinical Recommendations

    • Differentiating between structural and nonstructural causes is essential for appropriate treatment.
    • Continued research and understanding of AUB patterns are crucial for advancing clinical practices.

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    Description

    This quiz covers the clinical management guidelines set forth by the American College of Obstetricians and Gynecologists regarding the diagnosis of abnormal uterine bleeding in reproductive-aged women. Participants will assess their knowledge on menstrual flow variations and associated clinical practices. Perfect for obstetricians and gynecologists looking to refresh their understanding.

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