Podcast
Questions and Answers
What does DKA stand for?
What does DKA stand for?
- Diabetes keratosis application
- Diabetic ketosis anomaly
- Diabetic ketoacidosis (correct)
- Diabetic kidney attack
What is the primary condition associated with HHS?
What is the primary condition associated with HHS?
- Heavy hypercollagenosis syndrome
- Hyperosmolar hyperglycemic state (correct)
- Hypoglycemic hypertension syndrome
- Hypotensive hypoglycemia
Which organization provided the copyright for the content?
Which organization provided the copyright for the content?
- International Diabetes Federation
- American Diabetes Association (correct)
- American Heart Association
- Diabetes UK
What is the focus of the content regarding DKA and HHS?
What is the focus of the content regarding DKA and HHS?
In which year was the content published?
In which year was the content published?
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Study Notes
Diabetic Ketoacidosis (DKA)
- DKA is characterized by high blood ketone levels and metabolic acidosis.
- Commonly occurs in individuals with type 1 diabetes but can also occur in type 2 diabetes.
- Triggers include infections, insulin omissions, and severe stress conditions.
Hyperosmolar Hyperglycemic State (HHS)
- HHS is characterized by extremely high blood glucose levels without significant ketosis.
- More prevalent in patients with type 2 diabetes, often due to inadequate insulin action.
- Can be precipitated by dehydration, infections, and certain medications.
Pathogenesis Overview
- Both DKA and HHS involve insulin deficiency and increased counter-regulatory hormones (glucagon, cortisol).
- In DKA, insulin deficiency leads to increased lipolysis and ketogenesis.
- HHS results in severe hyperglycemia and osmotic diuresis, leading to fluid and electrolyte imbalances.
Clinical Significance
- Rapid recognition and treatment are essential to prevent complications.
- DKA can lead to cerebral edema, especially in children.
- HHS is associated with higher mortality rates compared to DKA.
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