Podcast
Questions and Answers
What is the primary cause of Diabetes Mellitus Type 1?
What is the primary cause of Diabetes Mellitus Type 1?
At what age is one more likely to develop Diabetes Mellitus Type 2?
At what age is one more likely to develop Diabetes Mellitus Type 2?
Which statement about insulin necessity in Diabetes Mellitus is true?
Which statement about insulin necessity in Diabetes Mellitus is true?
What distinguishes the obesity association between Type 1 and Type 2 diabetes?
What distinguishes the obesity association between Type 1 and Type 2 diabetes?
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Which condition is commonly seen in Diabetes Mellitus Type 1?
Which condition is commonly seen in Diabetes Mellitus Type 1?
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Which of the following best describes the key difference in the underlying mechanisms of Type 1 and Type 2 diabetes?
Which of the following best describes the key difference in the underlying mechanisms of Type 1 and Type 2 diabetes?
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A patient presents with severe glucose intolerance and is found to have HLA-DR3 and HLA-DR4 markers. Based on these findings, which type of diabetes is most likely?
A patient presents with severe glucose intolerance and is found to have HLA-DR3 and HLA-DR4 markers. Based on these findings, which type of diabetes is most likely?
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Which of the following is TRUE regarding the levels of serum insulin observed in Type 2 diabetes?
Which of the following is TRUE regarding the levels of serum insulin observed in Type 2 diabetes?
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Which of the following histological observations is most suggestive of Type 2 diabetes?
Which of the following histological observations is most suggestive of Type 2 diabetes?
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Why are prolonged exposure to epinephrine and glucocorticoid therapy relevant to Type 2 diabetes?
Why are prolonged exposure to epinephrine and glucocorticoid therapy relevant to Type 2 diabetes?
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A patient diagnosed with type 1 diabetes mellitus presents with a condition often involving elevated ketone bodies. Which of the following conditions is most likely?
A patient diagnosed with type 1 diabetes mellitus presents with a condition often involving elevated ketone bodies. Which of the following conditions is most likely?
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In type 2 diabetes mellitus, the presence of peripheral insulin resistance results in which of the following physiological responses?
In type 2 diabetes mellitus, the presence of peripheral insulin resistance results in which of the following physiological responses?
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A study of pancreatic tissue reveals a reduced number of beta cells with evidence of leukocytic infiltrate. This finding is most suggestive of which type of diabetes?
A study of pancreatic tissue reveals a reduced number of beta cells with evidence of leukocytic infiltrate. This finding is most suggestive of which type of diabetes?
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In a patient with type 2 diabetes, which of the following changes in serum insulin production is most likely to be seen over the course of the disease?
In a patient with type 2 diabetes, which of the following changes in serum insulin production is most likely to be seen over the course of the disease?
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While genetic predisposition exists for both forms of diabetes, the association for type 2 diabetes is considered:
While genetic predisposition exists for both forms of diabetes, the association for type 2 diabetes is considered:
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In the context of diabetes mellitus, a patient is diagnosed with a condition characterized by a high level of insulin sensitivity. What other finding would be most consistent with this diagnosis?
In the context of diabetes mellitus, a patient is diagnosed with a condition characterized by a high level of insulin sensitivity. What other finding would be most consistent with this diagnosis?
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A patient with a history of type 2 diabetes experiences a decrease in serum insulin levels over time. Which of the following factors most likely contributes to this change?
A patient with a history of type 2 diabetes experiences a decrease in serum insulin levels over time. Which of the following factors most likely contributes to this change?
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A tissue analysis from a diabetic patient reveals the presence of islet amyloid polypeptide (IAPP) deposits. This finding is most indicative of which condition?
A tissue analysis from a diabetic patient reveals the presence of islet amyloid polypeptide (IAPP) deposits. This finding is most indicative of which condition?
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In the context of diabetes, which description is the MOST consistent with aetiology, in the absence of specific lab results?
In the context of diabetes, which description is the MOST consistent with aetiology, in the absence of specific lab results?
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A patient, who is not obese, presents with a condition that necessitates insulin treatment. Of the factors listed, which one is most suggestive of Diabetes Mellitus Type 1?
A patient, who is not obese, presents with a condition that necessitates insulin treatment. Of the factors listed, which one is most suggestive of Diabetes Mellitus Type 1?
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Study Notes
Diabetes Mellitus Type 1
- Aetiology: Destruction of beta cells in the pancreas
- Insulin necessity: Always
- Age: Under 30 years old
- Obesity Association: No
- Genetic Predisposition: Weak
- HLA System Risk: HLA-DR3 and HLA-DR4, severe
- Glucose Intolerance: Not applicable
- Insulin Sensitivity: High
- Ketoacidosis: Common
- Number of Beta Cells: Decreased
- Serum Insulin Levels: Decreased
- Histology: Islet of leukocytic infiltrate - less common
- Nerve/Vascular Complications: Not applicable
Diabetes Mellitus Type 2
- Aetiology: Peripheral insulin resistance; also influenced by glucocorticoid therapy (Prednisone, dexamethasone, which can contribute to the issue). Prolonged epinephrine exposure can also play a factor.
- Insulin necessity: Sometimes
- Age: Over 40 years old
- Obesity Association: Yes
- Genetic Predisposition: Relatively strong
- HLA System Risk: None
- Glucose Intolerance: Mild/moderate
- Insulin Sensitivity: Low
- Ketoacidosis: Rare
- Number of Beta Cells: Variable (with amyloid deposits)
- Serum Insulin Levels: Initially increased, later decreased
- Histology: Islet of amyloid polypeptide (IAPP) Deposits - more common
- Nerve/Vascular Complications: Not applicable
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Description
This quiz explores the key differences between Type 1 and Type 2 Diabetes Mellitus. It covers aetiology, age of onset, insulin requirements, and genetic predisposition among other essential aspects. Test your understanding of these two distinct conditions!
