Diabetes Mellitus and Glucose Transporters Quiz
16 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary diagnostic criterion for diabetes mellitus according to the American Diabetes Association (ADA)?

  • A fasting plasma glucose level of 126 mg/dL or higher
  • A 2-hour plasma glucose level of 200 mg/dL or higher during an oral glucose tolerance test
  • A random plasma glucose level of 200 mg/dL or higher with classic symptoms of hyperglycemia
  • All of the above (correct)

Which glucose transporter is responsible for the rate-limiting step of glucose metabolism?

  • SGLT1
  • GLUT1
  • GLUT5
  • GLUT4 (correct)

What is the main function of the SGLT1 glucose transporter?

  • To transport glucose across the intestinal epithelium (correct)
  • To transport glucose out of cells
  • To transport glucose into cells
  • To transport glucose across the renal epithelium

Which of the following is a primary symptom of uncontrolled diabetes mellitus?

<p>Polyphagia (excessive hunger) (A)</p> Signup and view all the answers

What is the primary mechanism by which insulin lowers blood glucose levels?

<p>Both a and c (B)</p> Signup and view all the answers

Which type of diabetes is characterized by autoimmune destruction of pancreatic beta cells?

<p>Type 1 diabetes mellitus (A)</p> Signup and view all the answers

What is the primary cause of type 1 diabetes mellitus?

<p>Autoimmune destruction of pancreatic beta cells (D)</p> Signup and view all the answers

Which of the following is a key feature of type 2 diabetes mellitus?

<p>Insulin resistance (D)</p> Signup and view all the answers

What is the primary role of insulin in glucose homeostasis?

<p>Promoting glucose uptake and storage (C)</p> Signup and view all the answers

Which of the following glucose transporters is primarily responsible for insulin-stimulated glucose uptake in skeletal muscle and adipose tissue?

<p>GLUT4 (D)</p> Signup and view all the answers

What is the primary cause of gestational diabetes?

<p>Increased insulin resistance (C)</p> Signup and view all the answers

What is the normal range for blood glucose concentration?

<p>3.9-6.1 mmol/L (B)</p> Signup and view all the answers

Which pancreatic hormone is released by α-cells when blood glucose levels are low?

<p>Glucagon (B)</p> Signup and view all the answers

What enzyme deficiency leads to glycogen storage diseases?

<p>Glycogen phosphorylase deficiency (C)</p> Signup and view all the answers

Which disorder is characterized by hyperosmolar coma?

<p>Diabetic ketoacidosis (B)</p> Signup and view all the answers

What is the fasting plasma glucose level that meets the current WHO diagnostic criteria for diabetes?

<p>7.0 mmol/L (126 mg/dL) (A)</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser