Diabetes Mellitus and Glucose Transporters Quiz

Play an AI-generated podcast conversation about this lesson

What is the primary diagnostic criterion for diabetes mellitus according to the American Diabetes Association (ADA)?

A fasting plasma glucose level of 126 mg/dL or higher

A 2-hour plasma glucose level of 200 mg/dL or higher during an oral glucose tolerance test

A random plasma glucose level of 200 mg/dL or higher with classic symptoms of hyperglycemia

All of the above (correct)

Which glucose transporter is responsible for the rate-limiting step of glucose metabolism?

SGLT1

GLUT1

GLUT5

GLUT4 (correct)

What is the main function of the SGLT1 glucose transporter?

To transport glucose across the intestinal epithelium (correct)

To transport glucose out of cells

To transport glucose into cells

To transport glucose across the renal epithelium

Which of the following is a primary symptom of uncontrolled diabetes mellitus?

Polyphagia (excessive hunger) Signup and view all the answers

What is the primary mechanism by which insulin lowers blood glucose levels?

Both a and c Signup and view all the answers

Which type of diabetes is characterized by autoimmune destruction of pancreatic beta cells?

Type 1 diabetes mellitus Signup and view all the answers

What is the primary cause of type 1 diabetes mellitus?

Autoimmune destruction of pancreatic beta cells Signup and view all the answers

Which of the following is a key feature of type 2 diabetes mellitus?

Insulin resistance Signup and view all the answers

What is the primary role of insulin in glucose homeostasis?

Promoting glucose uptake and storage Signup and view all the answers

Which of the following glucose transporters is primarily responsible for insulin-stimulated glucose uptake in skeletal muscle and adipose tissue?

GLUT4 Signup and view all the answers

What is the primary cause of gestational diabetes?

Increased insulin resistance Signup and view all the answers

What is the normal range for blood glucose concentration?

3.9-6.1 mmol/L Signup and view all the answers

Which pancreatic hormone is released by α-cells when blood glucose levels are low?

Glucagon Signup and view all the answers

What enzyme deficiency leads to glycogen storage diseases?

Glycogen phosphorylase deficiency Signup and view all the answers

Which disorder is characterized by hyperosmolar coma?

Diabetic ketoacidosis Signup and view all the answers

What is the fasting plasma glucose level that meets the current WHO diagnostic criteria for diabetes?

7.0 mmol/L (126 mg/dL) Signup and view all the answers

Diabetes Mellitus and Glucose Transporters Quiz

Podcast Beta

Questions and Answers