10 Questions
How many grams of dextrose are required to prepare 3000 mL of a 5% solution?
150 g
What is the weight in grams of dextrose needed to make 1000 mL of a 10% solution?
100 g
To prepare 5000 mL of a 2% glucose solution, how many grams of glucose are required?
100 g
If you need to prepare 2500 mL of a 8% saline solution, how much salt in grams do you need?
250 g
What is the weight in grams of solute needed to make 3000 mL of a 7% solution?
210 g
How many grams of solute are required for 3500 mL of a 1% solution?
35 g
To make a 4% solution with a volume of 2000 mL, how much solute in grams is required?
80 g
What amount of solute in grams is needed for 4500 mL of a 12% solution?
540 g
How many grams of solute are necessary to create a 0.5% solution in 6000 mL of solvent?
30 g
To prepare 7000 mL of a 15% solution, how many grams of solute are needed?
1050 g
Study Notes
Percentage Concentration in Pharmaceutical Preparations
- Percentage concentration is used in pharmaceutical preparations when the dose of the active therapeutic ingredient (ATI) is not specific
- Three types of percentage concentration are used:
-
Percent weight in volume (w/v): expresses the number of grams of a constituent per 100 mL of solution or liquid preparation
- Expressed as: % w/v
- Example: Syrup g/mL
-
Percent volume in volume (v/v): expresses the number of milliliters of a constituent in 100 mL of solution or liquid preparation
- Expressed as: % v/v
- Example: d5W mL/mL
-
Percent weight in weight (w/w): expresses the number of grams of a constituent in 100g of solution or preparation
- Expressed as: % w/w
- Example: gel/tab g/g
-
Percent weight in volume (w/v): expresses the number of grams of a constituent per 100 mL of solution or liquid preparation
Calculations for Weight-in-Volume Concentration
- To prepare a 5% solution of dextrose, 4000 mL of solution requires:
- 4000 mL represents 4000 g of solution
- 5% = 0.05
- 4000 g x 0.05 = 200 g of dextrose
- Alternative solution using dimensional analysis: 5 g/100 mL * 4000 mL = 200 g of dextrose
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