Dermatology Basics: Layers of Skin

Questions and Answers

What is the primary function of the stratum corneum?

Cells actively proliferate

Contain melanin for skin color

Protection against environmental damage (correct)

Production of keratin

What is the role of lamellar granules found in the skin?

Assist in the proliferation of epidermal cells

Provide structural support to blood vessels

Produce melanin for pigmentation

Secrete lipids to maintain skin hydration (correct)

Which layer of the skin is primarily responsible for the synthesis of keratin?

Stratum lucidum

Stratum basale (correct)

Stratum granulosum

Stratum spinosum

What is the epidermal turnover time for a typical individual?

<p>8 weeks</p> Signup and view all the answers

Which component is NOT found in the stratum granulosum?

<p>Dendritic cells</p> Signup and view all the answers

Study Notes

Layers of Skin

The skin consists of multiple layers, each with distinct structures and functions.

Structure of the Epidermis

Stratum Corneum:
- Outermost layer composed of dead, flat cells lacking nuclei.
- Provides a protective barrier; notably thicker on palms and soles.
Stratum Lucidum:
- Present only in thick skin areas (palms and soles).
- Contains refractile granules of eleidin.
Stratum Granulosum:
- Characterized by keratohyalin granules, which produce filaggrin.
- Contains lamellar granules or Odland bodies that secrete lipids.
Stratum Spinosum:
- Contains dendritic cells and is known for its spiny appearance due to desmosomes.
- Plays a role in intercellular attachment among keratinocytes.
Stratum Basale (Stratum Germinativum):
- Innermost layer with high mitotic activity.
- Responsible for the proliferation of keratinocytes and skin renewal.

Additional Key Points

Epidermal Turnover Time (ETT):
- Refers to the duration for keratinocytes to migrate from the stratum basale to shedding, typically around 8 weeks (42-75 days).
- In conditions like psoriasis, epidermal turnover is significantly accelerated, with a turnover time of just 4 days.
Desmosomes:
- Intercellular structures vital for the stability and integrity of the epidermis by enabling attachment between keratinocytes.

Important Terms

Keratin Synthesis:
- A crucial process that occurs in the epidermal layers, particularly within the stratum spinosum and stratum granulosum, contributing to skin resilience and protection.

Description

Explore the fundamental layers of the skin in this quiz on dermatology. Test your knowledge on the structure and function of the epidermis, including various strata and their characteristics. Perfect for students and professionals seeking to deepen their understanding of skin anatomy.