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Dental Anesthesia and Pain Control: Local Anesthetics Neurophysiology

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Dental Anesthesia and Pain Control: Local Anesthetics Neurophysiology

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Questions and Answers

What is the primary mechanism of action of local anesthetics in dentistry?

Activating potassium channels in the nerve cell

Inhibiting calcium channels in the nerve cell

Blocking sodium channels in the nerve cell (correct)

Enhancing sodium channels in the nerve cell

Which of the following is a topic covered in 'Dental Anesthesia and Pain Control' course?

Principles of Restorative Dentistry

Pharmacology of Antibiotics

General Anesthesia in Dental Practice (correct)

Neurophysiology of Taste Perception

What is the purpose of using vasoconstrictors along with local anesthetics in dentistry?

To induce pain at the injection site

To dilate blood vessels at the injection site

To decrease the duration of anesthesia

To enhance the effect of local anesthetics (correct)

What is the purpose of supplemental injection techniques in dental anesthesia?

To achieve profound anesthesia in specific situations Signup and view all the answers

Which part of the nerve cell is affected by local anesthetics to produce local insensibility to pain stimuli?

Sodium channels Signup and view all the answers

What is the focus of 'Recent Advances and Future Trends in Pain Management' in dental practice?

Advancements in pain management and their potential application Signup and view all the answers

What determines the lipid solubility of local anesthetics?

The aromatic structure containing a benzene ring Signup and view all the answers

What is the primary mechanism by which local anesthetics exert their effects on the nerve membrane?

Blocking the voltage-dependent increase in sodium conductivity over the cell membrane Signup and view all the answers

What determines the degree of water solubility of local anesthetics?

The hydrophilic group containing a secondary or a tertiary amine Signup and view all the answers

Which form of the local anesthetic penetrates the lipid part of the membrane to produce a structural change, disturbing conduction in the neuron's membrane?

Non-ionized, lipophilic form (R3N) Signup and view all the answers

What percentage of the total activity of most local anesthetics is responsible for membrane expansion?

10% Signup and view all the answers

Which part of the molecule is not charged in tertiary amine and forms the non-ionized form showing lipophilic properties?

Aromatic chain Signup and view all the answers

What is responsible for approximately 90% of the total activity of most local anesthetics?

Interacting with the phospholipid phosphatidyl-L-serine in the neuronal membrane Signup and view all the answers

What part contains a hydrophilic group that determines the degree of water solubility in local anesthetics?

Intermediate section consisting of an ester or an amide group Signup and view all the answers

Which part determines whether local anesthetics are esters or amides?

The intermediate section consisting of an ester or an amide group Signup and view all the answers

What part determines whether local anesthetics are esters or amides?