Dental Anesthesia and Pain Control: Local Anesthetics Neurophysiology
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Questions and Answers

What is the primary mechanism of action of local anesthetics in dentistry?

  • Activating potassium channels in the nerve cell
  • Inhibiting calcium channels in the nerve cell
  • Blocking sodium channels in the nerve cell (correct)
  • Enhancing sodium channels in the nerve cell
  • Which of the following is a topic covered in 'Dental Anesthesia and Pain Control' course?

  • Principles of Restorative Dentistry
  • Pharmacology of Antibiotics
  • General Anesthesia in Dental Practice (correct)
  • Neurophysiology of Taste Perception
  • What is the purpose of using vasoconstrictors along with local anesthetics in dentistry?

  • To induce pain at the injection site
  • To dilate blood vessels at the injection site
  • To decrease the duration of anesthesia
  • To enhance the effect of local anesthetics (correct)
  • What is the purpose of supplemental injection techniques in dental anesthesia?

    <p>To achieve profound anesthesia in specific situations</p> Signup and view all the answers

    Which part of the nerve cell is affected by local anesthetics to produce local insensibility to pain stimuli?

    <p>Sodium channels</p> Signup and view all the answers

    What is the focus of 'Recent Advances and Future Trends in Pain Management' in dental practice?

    <p>Advancements in pain management and their potential application</p> Signup and view all the answers

    What determines the lipid solubility of local anesthetics?

    <p>The aromatic structure containing a benzene ring</p> Signup and view all the answers

    What is the primary mechanism by which local anesthetics exert their effects on the nerve membrane?

    <p>Blocking the voltage-dependent increase in sodium conductivity over the cell membrane</p> Signup and view all the answers

    What determines the degree of water solubility of local anesthetics?

    <p>The hydrophilic group containing a secondary or a tertiary amine</p> Signup and view all the answers

    Which form of the local anesthetic penetrates the lipid part of the membrane to produce a structural change, disturbing conduction in the neuron's membrane?

    <p>Non-ionized, lipophilic form (R3N)</p> Signup and view all the answers

    What percentage of the total activity of most local anesthetics is responsible for membrane expansion?

    <p>10%</p> Signup and view all the answers

    Which part of the molecule is not charged in tertiary amine and forms the non-ionized form showing lipophilic properties?

    <p>Aromatic chain</p> Signup and view all the answers

    What is responsible for approximately 90% of the total activity of most local anesthetics?

    <p>Interacting with the phospholipid phosphatidyl-L-serine in the neuronal membrane</p> Signup and view all the answers

    What part contains a hydrophilic group that determines the degree of water solubility in local anesthetics?

    <p>Intermediate section consisting of an ester or an amide group</p> Signup and view all the answers

    Which part determines whether local anesthetics are esters or amides?

    <p>The intermediate section consisting of an ester or an amide group</p> Signup and view all the answers

    What part determines whether local anesthetics are esters or amides?

    <p>The intermediate section consisting of an ester or an amide group</p> Signup and view all the answers

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