12 Questions
What is the main function of dendritic cells?
Initiating inflammation and stimulating adaptive immune responses
Where are mast cells found?
Skin, mucosal tissues, and most connective tissues
What activates mast cells as part of innate immunity?
Microbial products binding to TLRs
What do mast cell granules contain?
Vasoactive amines, proteolytic enzymes, lipid mediators, and cytokines
What is the role of mast cell products?
Defense against helminths and other pathogens, protection against snake and insect venoms, and responsible for allergic disease symptoms
What is the origin of tissue-resident macrophages in fetal life?
Yolk sac and liver
What do Innate Lymphoid Cells (ILCs) produce?
Cytokines similar to those secreted by helper T lymphocytes
What stimulates the responses of ILCs?
Cytokines produced by damaged epithelial and other cells at sites of infection
How are macrophages activated in innate immune responses?
Microbial products binding to TLRs and cytokines like interferon-γ (IFN-γ)
What promotes the phagocytosis of complement-coated microbes by macrophages?
Cell surface complement receptors
Where are ILCs always present?
Tissues
What is the contribution of ILCs to host defense or immunologic diseases?
Unclear, especially in humans
Test your knowledge on the functions of dendritic cells, which serve as sentinels in tissues, initiate inflammation, stimulate adaptive immune responses, capture protein antigens, and display antigen fragments to T cells.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
