Ch2pp35-37

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Questions and Answers

What is the main function of dendritic cells?

  • Initiating inflammation and stimulating adaptive immune responses (correct)
  • Killing bacteria with proteolytic enzymes
  • Producing histamine and vasoactive amines
  • Activating mast cells in the skin and mucosal tissues

Where are mast cells found?

  • Digestive system and respiratory system
  • Skin, mucosal tissues, and most connective tissues (correct)
  • Bone marrow and blood vessels
  • Lymph nodes and spleen

What activates mast cells as part of innate immunity?

  • Lymphocytes interacting with mast cells
  • Microbial products binding to TLRs (correct)
  • Proteolytic enzymes releasing histamine
  • Antibody-dependent mechanism

What do mast cell granules contain?

<p>Vasoactive amines, proteolytic enzymes, lipid mediators, and cytokines (A)</p> Signup and view all the answers

What is the role of mast cell products?

<p>Defense against helminths and other pathogens, protection against snake and insect venoms, and responsible for allergic disease symptoms (C)</p> Signup and view all the answers

What is the origin of tissue-resident macrophages in fetal life?

<p>Yolk sac and liver (B)</p> Signup and view all the answers

What do Innate Lymphoid Cells (ILCs) produce?

<p>Cytokines similar to those secreted by helper T lymphocytes (A)</p> Signup and view all the answers

What stimulates the responses of ILCs?

<p>Cytokines produced by damaged epithelial and other cells at sites of infection (D)</p> Signup and view all the answers

How are macrophages activated in innate immune responses?

<p>Microbial products binding to TLRs and cytokines like interferon-γ (IFN-γ) (D)</p> Signup and view all the answers

What promotes the phagocytosis of complement-coated microbes by macrophages?

<p>Cell surface complement receptors (D)</p> Signup and view all the answers

Where are ILCs always present?

<p>Tissues (B)</p> Signup and view all the answers

What is the contribution of ILCs to host defense or immunologic diseases?

<p>Unclear, especially in humans (B)</p> Signup and view all the answers

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