Podcast
Questions and Answers
What is the estimated percentage of older people in hospital who are affected by delirium?
What is the estimated percentage of older people in hospital who are affected by delirium?
What is the most significant non-modifiable risk factor for delirium in older people?
What is the most significant non-modifiable risk factor for delirium in older people?
What is the typical duration of delirium?
What is the typical duration of delirium?
What is delirium often the first presentation of?
What is delirium often the first presentation of?
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What is the consequence of delirium that should be assessed as a medical emergency?
What is the consequence of delirium that should be assessed as a medical emergency?
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What is delirium analogous to?
What is delirium analogous to?
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What is the increased risk of mortality in hospitalized patients with delirium?
What is the increased risk of mortality in hospitalized patients with delirium?
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What is the most significant risk factor for developing delirium?
What is the most significant risk factor for developing delirium?
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Which of the following medications is a risk factor for delirium?
Which of the following medications is a risk factor for delirium?
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What is a common consequence of delirium in patients?
What is a common consequence of delirium in patients?
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What is a characteristic of delirium in terms of duration?
What is a characteristic of delirium in terms of duration?
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Which of the following is a behavioral change associated with delirium?
Which of the following is a behavioral change associated with delirium?
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What is a cognitive impairment associated with delirium?
What is a cognitive impairment associated with delirium?
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What is a common emotional disturbance associated with delirium?
What is a common emotional disturbance associated with delirium?
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Which of the following is a risk factor for delirium in older adults?
Which of the following is a risk factor for delirium in older adults?
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What is a common consequence of delirium in terms of hospital stay?
What is a common consequence of delirium in terms of hospital stay?
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Which of the following symptoms is suggestive of a demyelinating etiology?
Which of the following symptoms is suggestive of a demyelinating etiology?
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What is the primary purpose of the neurologic history in neurologic assessment?
What is the primary purpose of the neurologic history in neurologic assessment?
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Which type of aphasia is characterized by a slow, halting manner of speech?
Which type of aphasia is characterized by a slow, halting manner of speech?
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What is the primary purpose of the Babinski sign in emergency situations?
What is the primary purpose of the Babinski sign in emergency situations?
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What is the focus of the physical exam in the neurological examination for Parkinson's disease?
What is the focus of the physical exam in the neurological examination for Parkinson's disease?
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What is the primary purpose of the falls risk assessment in the neurological examination for multiple sclerosis?
What is the primary purpose of the falls risk assessment in the neurological examination for multiple sclerosis?
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What is the focus of the physical exam in the neurological examination for peripheral neuropathy?
What is the focus of the physical exam in the neurological examination for peripheral neuropathy?
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What is the most important part of neurologic assessment?
What is the most important part of neurologic assessment?
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What is the significance of the Babinski sign in neurology?
What is the significance of the Babinski sign in neurology?
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What is brain health defined as?
What is brain health defined as?
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What is a person with hyperactive delirium likely to exhibit?
What is a person with hyperactive delirium likely to exhibit?
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What is the primary difference between delirium and dementia?
What is the primary difference between delirium and dementia?
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What is the term for a person experiencing both hyperactive and hypoactive delirium symptoms?
What is the term for a person experiencing both hyperactive and hypoactive delirium symptoms?
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What is the reason for under-diagnosis of delirium in hospitals?
What is the reason for under-diagnosis of delirium in hospitals?
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What is the goal of delirium prevention strategies?
What is the goal of delirium prevention strategies?
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What is brain health?
What is brain health?
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What is the most commonly used bedside assessment tool for delirium?
What is the most commonly used bedside assessment tool for delirium?
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What is the consequence of inadequate delirium prevention and management?
What is the consequence of inadequate delirium prevention and management?
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What is the primary reason for the difference in diagnosing delirium and dementia?
What is the primary reason for the difference in diagnosing delirium and dementia?
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What is the term used to describe the occurrence of delirium in a person with dementia?
What is the term used to describe the occurrence of delirium in a person with dementia?
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Study Notes
Delirium in Older People
- Delirium is a common cause of acute end-organ dysfunction in hospital settings and is associated with significant mortality.
- Delirium is not a disease, but rather a changed mental state characterized by disturbed consciousness, cognitive function, or perception.
- Delirium is often the first presentation of cognitive decline and can be thought of as “acute brain failure,” a multifactorial syndrome analogous to acute heart failure.
Risk Factors for Delirium
- Dementia is the most significant non-modifiable risk factor for delirium in older people, accounting for up to two-thirds of all occurrences.
- Other risk factors include:
- Advancing age (> 65 years)
- History of delirium
- Stroke
- Neurological disease
- Falls or gait disorder
- Hip fracture
- Multiple comorbidities
- Chronic renal or hepatic disease
Consequences of Delirium
- Patients need to stay longer in hospital or in critical care—with associated costs.
- The incidence of dementia increases.
- Patients acquire more hospital-acquired complications such as falls and pressure sores.
- Patients are more likely to need to be admitted to long-term care if they are in hospital.
- The rate of functional recovery is poor.
- The rate of mortality increases by 25% in patients with delirium.
Causes of Delirium
- Pre-existing cognitive impairment, such as dementia
- Older age
- Medical illness
- Visual and hearing impairment
- Functional impairment
- Depression
- History of alcohol abuse
- ICU stay
- Infections
- Pain
- Constipation
- Change in environment
- Physical restraints
- Lack of sleep
- Poor nutrition
- Medications
- Dehydration
- Electrolyte abnormalities
- Major surgery
- General anesthesia
- Anticholinergics, opiates, benzodiazepines, corticosteroids
- Alcohol withdrawal
- Sedative-hypnotic drug withdrawal
- Any newly prescribed medication
- Over-the-counter (OTC) remedies, especially those with anticholinergic effects
Delirium Assessment and Diagnosis
- Delirium has an acute onset and typically lasts several days, but can last for weeks to months in some cases.
- Delirium is often missed, even in hospitals, due to a lack of training and understanding that delirium is a medical emergency.
- Education programs are needed to train staff in delirium assessment, including the use of screening tools such as DSM-5, SQiD, CAM, 4AT, and UB-2.
Delirium vs. Dementia
- Delirium and dementia are both disorders where there is broad or widespread cognitive impairment.
- Delirium has a rapid onset and can fluctuate over hours and days.
- Dementia has a slow onset.
- Delirium is a medical emergency and requires rapid treatment, whereas dementia is a chronic condition that requires ongoing management.
Brain Health
- Brain health is the state of brain functioning across cognitive, sensory, social-emotional, behavioral, and motor domains that allows a person to realize their full potential over the life course, irrespective of the presence or absence of disorders.
- Conditions affecting the brain and nervous system emerge throughout the life course and are characterized by disruptions in brain growth, damage to brain structure, and/or impaired brain functioning.
- Timely diagnosis is crucial to ensure optimal disease management.
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Description
Learn about delirium in older adults, its prevalence in hospitals, and its effects on functional decline, independence, and mortality. Understand delirium as a changed mental state rather than a disease.