16 Questions
What is the most prevalent form of RNA editing in humans?
A to I editing
Which enzyme is responsible for RNA editing of apoB pre-mRNA in liver cells?
ADARs
What is the consequence of RNA editing in intestinal cell APOB mRNA?
Exon 26 CAA coding edited to a UAA stop codon
What is the significance of RNA editing in Antarctic octopus?
Altering amino acid sequence of potassium channel
What is the function of S. cerevisiae Ira protein?
GTPase activating protein that activates GTPase activity of Ras
What is the consequence of defective NF1 in humans?
Abnormally high Ras signaling and excessive cell division
What is the main effect of doublesex RNAi in large males?
Reduces the size of large horns
What is the impact of low temperatures on nerve cells in octopus?
Delays K+ channels closing, hindering neuron’s ability to fire
What is deep homology?
Similarity due to shared ancestry between structures or genes in different taxa
What can gene duplication lead to?
Neofunctionalization and subfunctionalization
What is LUCA in the context of evolutionary biology?
Last universal common ancestor of all extant life
What is the RNA World hypothesis about?
Early synthesis and random polymerization of nucleotides leading to emergence of functional ribozymes
What is the result of evolutionary co-option of sex determination pathway in beetle horn plasticity?
Males and females having unique doublesex isoforms
What is the function of gene flow in evolution?
Transfer of genetic material between populations
What is the role of natural selection in evolution?
Favoring traits that increase an organism's chances of survival and reproduction
What is the source of genomic variation through recombination?
Generation of longer oligomers that can fold into structures of varying complexity
Test your knowledge of deep homology with this quiz! Explore the concepts of gene duplication, subfunctionalization, and the ancient heart gene regulatory network to understand the similarities and differences between structures and genes in different taxa.
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