Podcast
Questions and Answers
What is the prevalence of schizophrenia per 1000 persons?
What is the prevalence of schizophrenia per 1000 persons?
- 5.5
- 8.5
- 7.1
- 6.2 (correct)
What is associated with a more benign course of schizophrenia?
What is associated with a more benign course of schizophrenia?
- Late onset of symptoms in women (correct)
- Exposure to certain viruses prenatally
- Early onset of symptoms in men
- Higher levels of dopamine
What is a characteristic of the negative syndrome of schizophrenia?
What is a characteristic of the negative syndrome of schizophrenia?
- Continuous social, occupational, and symptom impairment (correct)
- Excessive stress
- Periods of remission or recovery
- Brain atrophy
What is a factor that affects the prognosis of schizophrenia?
What is a factor that affects the prognosis of schizophrenia?
What is true about the positive syndrome of schizophrenia?
What is true about the positive syndrome of schizophrenia?
What is a characteristic of people with schizophrenia?
What is a characteristic of people with schizophrenia?
What is a factor associated with recovering from schizophrenia?
What is a factor associated with recovering from schizophrenia?
What is true about the epidemiology of schizophrenia?
What is true about the epidemiology of schizophrenia?
What is a possible cause of schizophrenia?
What is a possible cause of schizophrenia?
What is a structural anomaly found in the brains of people with schizophrenia?
What is a structural anomaly found in the brains of people with schizophrenia?
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Study Notes
Common Myths about Schizophrenia
- Myth #1: Schizophrenia does not mean "split personality"
- Myth #2: It is not caused by bad parenting
- Myth #3: It is not caused by drug experimentation
- Myth #4: It is not a lack of motivation
- Myth #5: The incidence of schizophrenia is not rising
- Myth #6: It does not always lead to institutionalization and disability
- Myth #7: It is not related to low intelligence
- Myth #8: People with schizophrenia are not always dangerous and violent
Famous People with Schizophrenia
- John Nash, a Nobel Prize winner in Math
- Van Gogh, a famous artist
Medical Management
- Antipsychotic medication: clozapine, risperidone, asenapine, and olanzapine
- These medications decrease positive symptoms, but do not cure schizophrenia
- Side effects: autonomic nervous system signs, endocrine side effects, weight gain, and skin changes
- Close monitoring of drug trials is essential
- A major concern is non-compliance with medication
Assessment
- Goal setting: using the Canadian Occupational Performance Measure (COPM)
- ADL: Assessment of ADL of Personal Life Skills (PLS) using the Milwaukee Evaluation of Daily Living Skills (MEDLS)
- Leisure: Leisure and Activity Configuration, Activity Card
- Motor skills: Assessment of Motor and Process Skills (AMPS)
- Emotional: The Hospital Anxiety and Depression Scale (HADS)
- Function: The Functional Levels Outcome Measure (FLOM)
Goal Setting
- SMART goals
- Based on functional activities
- Integrates goals from patients and family members
- Takes into consideration the expected prognosis (positive vs. negative)
Schizophrenia Definition
- Primarily a disorganization of thinking
- Can result in grossly disorganized behavior, hallucinations, delusions, and deterioration of ADL skills
Schizophrenia Symptoms
- Positive symptoms: delusions, hallucinations, disorganized thinking, and grossly disorganized behavior
- Negative symptoms: reduced emotional expression, alogia, anhedonia, asociality, avolition, and inattention
Other Symptoms of Concern to OT
- Lack of interest in eating (delusions may be an interfering factor)
- Abnormalities of psychomotor activity
- Concentration, attention, and memory difficulties
- Poor psychosocial functioning
- Depersonalization and derealization
- Somatic concerns, such as digestive or weight problems
- Anxieties and phobias
- Hallucinations, which can lead to profound dysfunction in daily life
- Suicide (10% of people with schizophrenia succeed, and 20-40% attempt)
Etiology of Schizophrenia
- Structural anomalies in the brain, including lesions in the brain stem, enlargement of the ventricles, brain atrophy, and abnormalities in the limbic structures, cerebellum, and corpus callosum
- Excess of dopamine or an excessive quantity of dopamine receptors
- Possible cause: exposure to certain viruses prenatally
- Heredity and excessive stress are also contributing factors
Epidemiology
- 6.2 per 1000 persons (Orrico-Sanchez, 2020)
- Greater prevalence in men than women
- Women tend to have a later onset and a more benign course
Prognosis
- A 20-year longitudinal study showed different rates of recovery for those with negative compared to positive symptoms of schizophrenia
- The negative syndrome represents a persistently impaired subsample of schizophrenia patients
- Factors associated with recovering from schizophrenia: shorter durations of untreated psychosis, coping and problem-solving skills, and cultural and environmental influences.
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