30 Questions
Which of the following is NOT an indication for the use of antipsychotics?
Treatment of hypertension
Which type of antipsychotics has a higher risk for extrapyramidal side effects like acute dystonias?
Typical antipsychotics
What do typical antipsychotics primarily block to exert their action?
Dopamine receptors
Which receptors do atypical antipsychotics primarily antagonize?
Serotonin type 2A receptors
In which disorder are antipsychotics used to control tics and vocal utterances?
Tourette's disorder
What do atypical antipsychotics have lower affinity for compared to typical antipsychotics?
Dopamine receptors
Which of the following antipsychotic drugs is contraindicated in patients with a history of clozapine-induced agranulocytosis?
Clozapine
In which group of patients should caution be taken when administering antipsychotic drugs?
Patients with a history of seizures
Which antipsychotic drug is contraindicated in patients with concurrent use of strong CYP3A4 inducers?
Lurasidone
In which patients should caution be taken when administering antipsychotic drugs?
Patients with a history of hypotension
Which of the listed antipsychotic drugs is contraindicated in patients with uncontrolled epilepsy?
Iloperidone
Which group of patients is safety not established for when administering antipsychotic drugs?
Pregnant clients
What is the purpose of the risk evaluation and mitigation strategy (REMS) program for clozapine?
To monitor, manage, and report the risk for agranulocytosis
Which patient population is identified as being most at risk for developing pseudoparkinsonism as an extrapyramidal side effect?
Women
What characterizes akathisia as an extrapyramidal side effect?
Continuous restlessness and fidgeting
What happens when dystonia, an extrapyramidal side effect, progresses untreated?
It can cause laryngospasms and be fatal
What defines agranulocytosis as a serious condition?
Low absolute neutrophil count (ANC)
When do symptoms of akinesia typically appear following initiation of antipsychotic medication?
1 to 5 days after therapy begins
In which of the following conditions are typical antipsychotics contraindicated?
Patients with acid reflux
Which group of patients should caution be taken when administering typical antipsychotics?
Diabetic clients
What is a significant risk associated with atypical antipsychotics in the elderly population?
Metabolic disturbances like weight gain
Which condition is a contraindication for atypical antipsychotics?
Lactation
What is a common side effect associated with typical antipsychotics in the elderly population?
Increased risk of falls
Which of the following is NOT a contraindication for typical antipsychotics?
Diabetic patients
What are the common CYP3A4 inducers that may decrease the effects of zaleplon?
Rifampin and phenytoin
Which medication can lead to life-threatening cardiac arrhythmias when used concomitantly with zolpidem?
Amiodarone
What is a substance that can increase the effects of zolpidem?
Alcohol
Which medication, when used concurrently with zaleplon, can lead to increased effects of zaleplon?
Cimetidine
What are the substances that can lead to increased effects of ramelteon?
Rifampin and ketoconazole
Which CNS depressants can lead to increased effects of zolpidem?
Selective serotonin reuptake inhibitors
Test your knowledge on contraindications for typical and atypical antipsychotics according to the Davis Company guidelines. Questions cover contraindications in hypersensitive, comatose, severely depressed patients, elderly patients with dementia-related psychosis, and patients with QT prolongation or heart issues.
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