Cytomegalovirus Diagnosis Methods and Markers

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What is the most common cause of heterophile-negative mononucleosis?

Cytomegalovirus (correct)

Herpes simplex virus

Varicella-zoster virus

Epstein-Barr virus

Which family of viruses does Human CMV belong to?

Herpesviruses (correct)

Flaviviruses

Orthomyxoviruses

Retroviruses

Where does CMV rest in the body after spreading to the lymphoid tissues?

Endothelial cells

Nervous tissues

Epithelial cells (correct)

Muscle tissues

Which group is at the greatest risk of CMV infection?

Fetuses and immunocompromised persons Signup and view all the answers

In which year was CMV first isolated in the laboratory?

1956 Signup and view all the answers

What kind of genetic material does CMV possess?

Linear double-stranded DNA Signup and view all the answers

What is the preferred method for diagnosing Cytomegalovirus infection?

PCR Signup and view all the answers

Which histological mark is characteristic of Cytomegalovirus infection?

Basophilic intranuclear inclusion with an 'OWL'S EYE' Signup and view all the answers

What does IgG Avidity testing measure in Cytomegalovirus infection?

Recent primary infection Signup and view all the answers

Which blood parameter is typically abnormal in Cytomegalovirus infection?

Leukocytosis with >20% atypical lymphocytes Signup and view all the answers

In which group of patients is CMV serology NOT RECOMMENDED?

Immunocompromised patients Signup and view all the answers

What is the gold standard test for tissue Cytomegalovirus detection?

Cell culture with immunofluorescence Signup and view all the answers

Which mode of transmission is NOT associated with Cytomegalovirus (CMV) infection?

Blood transfusion (must be leukocyte-reduced or irradiated) Signup and view all the answers

What is a common manifestation of disseminated CMV infection?

Interstitial pneumonitis Signup and view all the answers

Which group is more likely to have Cytomegalovirus (CMV) in their urine or saliva?

Young children Signup and view all the answers

What is a common immunologic manifestation of Cytomegalovirus (CMV) infection?

Meningoencephalitis Signup and view all the answers

Which statement is true about CMV-positive individuals?

They usually do not have the virus in urine or saliva. Signup and view all the answers

Which complication is NOT commonly associated with Cytomegalovirus (CMV) infection?

Sore throat Signup and view all the answers