Cytomegalovirus Diagnosis Methods and Markers
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Questions and Answers

What is the most common cause of heterophile-negative mononucleosis?

  • Cytomegalovirus (correct)
  • Herpes simplex virus
  • Varicella-zoster virus
  • Epstein-Barr virus
  • Which family of viruses does Human CMV belong to?

  • Herpesviruses (correct)
  • Flaviviruses
  • Orthomyxoviruses
  • Retroviruses
  • Where does CMV rest in the body after spreading to the lymphoid tissues?

  • Endothelial cells
  • Nervous tissues
  • Epithelial cells (correct)
  • Muscle tissues
  • Which group is at the greatest risk of CMV infection?

    <p>Fetuses and immunocompromised persons</p> Signup and view all the answers

    In which year was CMV first isolated in the laboratory?

    <p>1956</p> Signup and view all the answers

    What kind of genetic material does CMV possess?

    <p>Linear double-stranded DNA</p> Signup and view all the answers

    What is the preferred method for diagnosing Cytomegalovirus infection?

    <p>PCR</p> Signup and view all the answers

    Which histological mark is characteristic of Cytomegalovirus infection?

    <p>Basophilic intranuclear inclusion with an 'OWL'S EYE'</p> Signup and view all the answers

    What does IgG Avidity testing measure in Cytomegalovirus infection?

    <p>Recent primary infection</p> Signup and view all the answers

    Which blood parameter is typically abnormal in Cytomegalovirus infection?

    <p>Leukocytosis with &gt;20% atypical lymphocytes</p> Signup and view all the answers

    In which group of patients is CMV serology NOT RECOMMENDED?

    <p>Immunocompromised patients</p> Signup and view all the answers

    What is the gold standard test for tissue Cytomegalovirus detection?

    <p>Cell culture with immunofluorescence</p> Signup and view all the answers

    Which mode of transmission is NOT associated with Cytomegalovirus (CMV) infection?

    <p>Blood transfusion (must be leukocyte-reduced or irradiated)</p> Signup and view all the answers

    What is a common manifestation of disseminated CMV infection?

    <p>Interstitial pneumonitis</p> Signup and view all the answers

    Which group is more likely to have Cytomegalovirus (CMV) in their urine or saliva?

    <p>Young children</p> Signup and view all the answers

    What is a common immunologic manifestation of Cytomegalovirus (CMV) infection?

    <p>Meningoencephalitis</p> Signup and view all the answers

    Which statement is true about CMV-positive individuals?

    <p>They usually do not have the virus in urine or saliva.</p> Signup and view all the answers

    Which complication is NOT commonly associated with Cytomegalovirus (CMV) infection?

    <p>Sore throat</p> Signup and view all the answers

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