Cytomegalovirus Diagnosis Methods and Markers
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Questions and Answers

What is the most common cause of heterophile-negative mononucleosis?

  • Cytomegalovirus (correct)
  • Herpes simplex virus
  • Varicella-zoster virus
  • Epstein-Barr virus

Which family of viruses does Human CMV belong to?

  • Herpesviruses (correct)
  • Flaviviruses
  • Orthomyxoviruses
  • Retroviruses

Where does CMV rest in the body after spreading to the lymphoid tissues?

  • Endothelial cells
  • Nervous tissues
  • Epithelial cells (correct)
  • Muscle tissues

Which group is at the greatest risk of CMV infection?

<p>Fetuses and immunocompromised persons (B)</p> Signup and view all the answers

In which year was CMV first isolated in the laboratory?

<p>1956 (A)</p> Signup and view all the answers

What kind of genetic material does CMV possess?

<p>Linear double-stranded DNA (B)</p> Signup and view all the answers

What is the preferred method for diagnosing Cytomegalovirus infection?

<p>PCR (A)</p> Signup and view all the answers

Which histological mark is characteristic of Cytomegalovirus infection?

<p>Basophilic intranuclear inclusion with an 'OWL'S EYE' (D)</p> Signup and view all the answers

What does IgG Avidity testing measure in Cytomegalovirus infection?

<p>Recent primary infection (C)</p> Signup and view all the answers

Which blood parameter is typically abnormal in Cytomegalovirus infection?

<p>Leukocytosis with &gt;20% atypical lymphocytes (B)</p> Signup and view all the answers

In which group of patients is CMV serology NOT RECOMMENDED?

<p>Immunocompromised patients (A)</p> Signup and view all the answers

What is the gold standard test for tissue Cytomegalovirus detection?

<p>Cell culture with immunofluorescence (D)</p> Signup and view all the answers

Which mode of transmission is NOT associated with Cytomegalovirus (CMV) infection?

<p>Blood transfusion (must be leukocyte-reduced or irradiated) (B)</p> Signup and view all the answers

What is a common manifestation of disseminated CMV infection?

<p>Interstitial pneumonitis (A)</p> Signup and view all the answers

Which group is more likely to have Cytomegalovirus (CMV) in their urine or saliva?

<p>Young children (C)</p> Signup and view all the answers

What is a common immunologic manifestation of Cytomegalovirus (CMV) infection?

<p>Meningoencephalitis (B)</p> Signup and view all the answers

Which statement is true about CMV-positive individuals?

<p>They usually do not have the virus in urine or saliva. (A)</p> Signup and view all the answers

Which complication is NOT commonly associated with Cytomegalovirus (CMV) infection?

<p>Sore throat (A)</p> Signup and view all the answers

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