Cytomegalovirus (CMV) Biology Quiz
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Questions and Answers

Which cell type does CMV establish latency in?

  • B cells
  • Hematopoietic progenitor cells (correct)
  • NK cells
  • T cells
  • What is one mechanism by which CMV prevents antigen presentation to T cells?

  • Promoting MHC I expression
  • Inhibiting MHC I molecule expression (correct)
  • Enhancing NK cell function
  • Activating CD4 T cells
  • In which body fluids can CMV be shed?

  • Sweat
  • Breast milk (correct)
  • Cerebrospinal fluid
  • Tears
  • What is a common symptom of CMV mononucleosis?

    <p>Splenomegaly</p> Signup and view all the answers

    How is CMV transmitted in patients attending sexually transmitted disease clinics?

    <p>Sexually transmitted</p> Signup and view all the answers

    What is the mechanism by which CMV prevents antigen presentation to natural killer (NK) cells?

    <p>Preventing expression of MHC I molecules</p> Signup and view all the answers

    In CMV mononucleosis, why is heterophile antibody not present, unlike in EBV infection?

    <p>CMV infects and activates B cells</p> Signup and view all the answers

    What is a characteristic feature of CMV infection in transplant recipients during periods of intense immunosuppression?

    <p>Pulmonary infection with interstitial mononuclear infiltrate</p> Signup and view all the answers

    How does CMV establish latency in the body?

    <p>In hematopoietic progenitor cells in bone marrow</p> Signup and view all the answers

    Which organ is primarily affected in CMV infection in solid-organ transplant recipients?

    <p>Lung</p> Signup and view all the answers

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