Cytomegalovirus (CMV) Biology Quiz
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Questions and Answers

Which cell type does CMV establish latency in?

  • B cells
  • Hematopoietic progenitor cells (correct)
  • NK cells
  • T cells

What is one mechanism by which CMV prevents antigen presentation to T cells?

  • Promoting MHC I expression
  • Inhibiting MHC I molecule expression (correct)
  • Enhancing NK cell function
  • Activating CD4 T cells

In which body fluids can CMV be shed?

  • Sweat
  • Breast milk (correct)
  • Cerebrospinal fluid
  • Tears

What is a common symptom of CMV mononucleosis?

<p>Splenomegaly (D)</p> Signup and view all the answers

How is CMV transmitted in patients attending sexually transmitted disease clinics?

<p>Sexually transmitted (A)</p> Signup and view all the answers

What is the mechanism by which CMV prevents antigen presentation to natural killer (NK) cells?

<p>Preventing expression of MHC I molecules (A)</p> Signup and view all the answers

In CMV mononucleosis, why is heterophile antibody not present, unlike in EBV infection?

<p>CMV infects and activates B cells (C)</p> Signup and view all the answers

What is a characteristic feature of CMV infection in transplant recipients during periods of intense immunosuppression?

<p>Pulmonary infection with interstitial mononuclear infiltrate (B)</p> Signup and view all the answers

How does CMV establish latency in the body?

<p>In hematopoietic progenitor cells in bone marrow (B)</p> Signup and view all the answers

Which organ is primarily affected in CMV infection in solid-organ transplant recipients?

<p>Lung (B)</p> Signup and view all the answers

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