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Questions and Answers
What are the two main components of a spindle fiber?
What are the two main components of a spindle fiber?
What is the function of the kinetochore?
What is the function of the kinetochore?
During which phase of mitosis do the chromosomes become visible?
During which phase of mitosis do the chromosomes become visible?
What is the purpose of the spindle fibers?
What is the purpose of the spindle fibers?
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What happens to the nuclear envelope during prophase?
What happens to the nuclear envelope during prophase?
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During which phase of mitosis do the sister chromatids separate?
During which phase of mitosis do the sister chromatids separate?
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What is the function of the aster?
What is the function of the aster?
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What happens after mitosis?
What happens after mitosis?
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What is the result of the replication process in a coli cell?
What is the result of the replication process in a coli cell?
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What is the term for the development of cancerous cells with specific characteristics?
What is the term for the development of cancerous cells with specific characteristics?
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What is the main characteristic of benign tumors?
What is the main characteristic of benign tumors?
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What is the purpose of the contractile ring in cytokinesis?
What is the purpose of the contractile ring in cytokinesis?
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What is the purpose of angiogenesis in cancer cells?
What is the purpose of angiogenesis in cancer cells?
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What is the result of metastasis in cancer cells?
What is the result of metastasis in cancer cells?
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What is the role of the Golgi apparatus in plant cell cytokinesis?
What is the role of the Golgi apparatus in plant cell cytokinesis?
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What is the function of the G1 checkpoint?
What is the function of the G1 checkpoint?
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What is the purpose of cancer treatment?
What is the purpose of cancer treatment?
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What is the term for cancer of the blood?
What is the term for cancer of the blood?
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What is the role of p53 protein?
What is the role of p53 protein?
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What is the function of the RB protein?
What is the function of the RB protein?
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What is the characteristic of cancer cells in terms of their nuclei?
What is the characteristic of cancer cells in terms of their nuclei?
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What is the purpose of the G2 checkpoint?
What is the purpose of the G2 checkpoint?
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What is the role of the M checkpoint?
What is the role of the M checkpoint?
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What happens if DNA damage is not corrected during the G1 checkpoint?
What happens if DNA damage is not corrected during the G1 checkpoint?
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What is the cell cycle?
What is the cell cycle?
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What is the longest stage of the cell cycle?
What is the longest stage of the cell cycle?
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What happens during the G1 phase?
What happens during the G1 phase?
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What is the purpose of the S phase?
What is the purpose of the S phase?
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What happens during the G2 phase?
What happens during the G2 phase?
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What is the result of mitosis?
What is the result of mitosis?
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What is the role of spindle fibers in mitosis?
What is the role of spindle fibers in mitosis?
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What is the result of cytokinesis?
What is the result of cytokinesis?
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What is the purpose of radiation therapy in cancer treatment?
What is the purpose of radiation therapy in cancer treatment?
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Which of the following is NOT a protective behavior against cancer?
Which of the following is NOT a protective behavior against cancer?
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What is the purpose of hormonal therapy in cancer treatment?
What is the purpose of hormonal therapy in cancer treatment?
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What is the effect of excessive alcohol consumption on cancer risk?
What is the effect of excessive alcohol consumption on cancer risk?
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What is the purpose of chemotherapy in cancer treatment?
What is the purpose of chemotherapy in cancer treatment?
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What is a recommended dietary guideline for reducing cancer risk?
What is a recommended dietary guideline for reducing cancer risk?
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Study Notes
The Cell Cycle
- The cell cycle spans the period of time from the production of a daughter cell to the cellular reproduction of that cell to produce two new daughter cells.
- The cell cycle consists of two main stages: Mitotic (M) phase and Interphase.
Interphase
- A cell spends most of its existence in Interphase, where it performs normal activities and functions.
- Interphase has three stages: G1, S, and G2.
- During G1, the cell grows and doubles its organelles and resources in preparation for DNA replication.
- During S, DNA replication begins to create a duplicate DNA strand, resulting in sister chromatids.
- During G2, the cell synthesizes proteins needed for cell division.
Mitotic (M) Phase
- The M phase consists of Mitosis and Cytokinesis.
- Mitosis is the division of nuclear material (DNA), producing two genetically identical daughter chromosomes.
- Cytokinesis is the division of the cytoplasm and its contents, resulting in two daughter cells with the same number of chromosomes as the original cell.
Mitosis and Cytokinesis
- The separation of sister chromatids during mitosis occurs in four phases: Prophase, Metaphase, Anaphase, and Telophase.
- The spindle fibers, organized by the centrosome, attach to each duplicated chromosome at the kinetochore, facilitating the separation of sister chromatids.
- In animal cells, centrosomes consist of two centrioles and an array of microtubules called an aster.
- Cytokinesis in plant cells occurs by forming a new cell wall between the daughter cells, with the Golgi apparatus producing vesicles that fuse to form the cell plate.
The Cell Cycle Control System
- The cell cycle is tightly regulated to ensure it is completed correctly.
- The control system has checkpoints that control the progression of the cell cycle, ensuring that the stages of interphase occur sequentially in the correct order.
- The G1 checkpoint is important, as passing this point commits the cell to division.
- Proteins like p53 and RB protein regulate the cell cycle, stopping it at the G1 checkpoint if DNA is damaged and initiating DNA repair.
Cancer and the Cell Cycle
- Cancer is a disease of the cell cycle, characterized by uncontrolled cell division.
- Cancer cells lack differentiation, have abnormally large nuclei, and/or nuclei with an abnormal number of chromosomes.
- Cancer cells form a mass of dividing cells called a tumor, which can undergo metastasis.
- Cancer treatments include surgery, radiation therapy, chemotherapy, and hormonal therapy.
Prevention of Cancer
- Evidence suggests that certain lifestyle changes can reduce the risk of certain types of cancer.
- Adopting protective behaviors, such as avoiding potentially harmful activities, and following a protective diet can help reduce the risk of cancer.
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Description
Learn about the process of cytokinesis in plant and animal cells, including the formation of contractile rings and cell plates.