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The direct reversal DNA repair mechanism involves the use of a template to repair DNA damage.
False
Photoreactivation is a direct reversal DNA repair mechanism that can reverse the formation of pyrimidine dimers induced by UV light.
True
Methylation of guanine bases results in a DNA structure complimentary to cytosine.
False
Photo reactivating enzyme requires the presence of light for its repair function.
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Direct reversal through methylation can reverse the alkylation of guanine at O6 position.
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Photo reactivation through destruction of abnormal covalent bonds occurs in humans.
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Direct reversal DNA repair mechanism is mainly classified into photoreactivation and methylation.
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The direct reversal mechanism involves replacing damaged nucleotide bases.
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Methyl guanine methyl transferase (MGMT) restores the original guanine by transferring the methylation product to its active site.
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Direct reversal mechanisms are not impacted by environmental factors.
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