Cyt c and the Electron Transport Chain

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Questions and Answers

Which of the following is true about the location of Cyt c in the inner membrane?

  • It is embedded within the membrane bilayer
  • It is associated with the outer surface of the inner membrane (correct)
  • It is located in the intermembrane space
  • It is associated with the inner surface of the inner membrane

What surrounds the heme crevice on the surface of Cyt c?

  • Negatively charged anionic residues
  • Negatively charged lysine residues
  • Positively charged lysine residues (correct)
  • Positively charged anionic residues

What is the role of Cyt c in electron transfer?

  • It accepts electrons from oxygen and donates them to complex IV
  • It accepts electrons from complex III and donates them to complex IV
  • It accepts electrons from complex IV and donates them to oxygen (correct)
  • It accepts electrons from complex IV and donates them to complex III

How many net H+ are pumped across the membrane during electron transfer in complex IV?

<p>2 (C)</p> Signup and view all the answers

Where does Cyt c dock on the membrane during electron transfer to complex IV?

<p>P side of the membrane (B)</p> Signup and view all the answers

What is the effect of cyanide on electron transfer in complex IV?

<p>It blocks electron transfer (D)</p> Signup and view all the answers

Which type of mechanism is used by complex IV to pump H+ across the membrane?

<p>Conformational-type mechanism (D)</p> Signup and view all the answers

What is the final product of electron transfer in complex IV?

<p>Water (B)</p> Signup and view all the answers

What is the function of complex IV in the electron transport chain?

<p>To donate electrons to oxygen (B)</p> Signup and view all the answers

What is the oxidation state of the heme group in Cyt c after donating an electron to complex IV?

<p>Fe3+ (C)</p> Signup and view all the answers

Which of the following is true about the interaction between Cyt c and membrane complexes?

<p>Cyt c binds to membrane complexes through electrostatic interactions (B)</p> Signup and view all the answers

Which complex in the electron transport chain is responsible for pumping the most H+ across the membrane?

<p>Complex I (A)</p> Signup and view all the answers

Which of the following is true about the location of Cyt c in the inner membrane?

<p>It is associated with the outer surface of the inner membrane (B)</p> Signup and view all the answers

What surrounds the heme crevice on the surface of Cyt c?

<p>Positively charged lysine residues (A)</p> Signup and view all the answers

What is the role of Cyt c in electron transfer?

<p>It accepts electrons from complex IV and donates them to oxygen (C)</p> Signup and view all the answers

How many net H+ are pumped across the membrane during electron transfer in complex IV?

<p>2 (D)</p> Signup and view all the answers

Where does Cyt c dock on the membrane during electron transfer to complex IV?

<p>P side of the membrane (C)</p> Signup and view all the answers

What is the effect of cyanide on electron transfer in complex IV?

<p>It blocks electron transfer (B)</p> Signup and view all the answers

Which type of mechanism is used by complex IV to pump H+ across the membrane?

<p>Conformational-type mechanism (B)</p> Signup and view all the answers

What is the final product of electron transfer in complex IV?

<p>Water (C)</p> Signup and view all the answers

What is the function of complex IV in the electron transport chain?

<p>To donate electrons to oxygen (A)</p> Signup and view all the answers

What is the oxidation state of the heme group in Cyt c after donating an electron to complex IV?

<p>Fe3+ (D)</p> Signup and view all the answers

Which of the following is true about the interaction between Cyt c and membrane complexes?

<p>Cyt c binds to membrane complexes through electrostatic interactions (D)</p> Signup and view all the answers

Which complex in the electron transport chain is responsible for pumping the most H+ across the membrane?

<p>Complex I (C)</p> Signup and view all the answers

Which of the following is true about Cyt c?

<p>It is a water soluble protein (B)</p> Signup and view all the answers

What surrounds the heme crevice on the surface of Cyt c?

<p>Positively charged lysine residues (D)</p> Signup and view all the answers

What is the role of anionic residues on membrane complexes in relation to Cyt c?

<p>They interact with positively charged lysine residues on Cyt c (A)</p> Signup and view all the answers

Which complex accepts electrons one at a time from Cyt C and donates them to oxygen to form water?

<p>Complex IV (D)</p> Signup and view all the answers

How many net H+ are pumped across the membrane during electron transfer from Cyt C to Complex IV?

<p>2 (B)</p> Signup and view all the answers

Where does Cyt C dock on the membrane during electron transfer to Complex IV?

<p>P side of the membrane (B)</p> Signup and view all the answers

What is the effect of cyanide on electron transfer in Complex IV?

<p>It inhibits electron transfer (A)</p> Signup and view all the answers

What is the charge of lysine residues surrounding the heme crevice on the surface of Cyt C?

<p>Positively charged (A)</p> Signup and view all the answers

What is the mechanism by which H+ ions are pumped across the membrane during electron transfer from Cyt C to Complex IV?

<p>Conformational-type mechanism (D)</p> Signup and view all the answers

What is the role of CuA in electron transfer from Cyt C to Complex IV?

<p>It accepts the electron leading to oxidation of the heme group in Cyt C (C)</p> Signup and view all the answers

What is the effect of blocking electron transfer in Complex IV?

<p>It inhibits electron transfer in other complexes (B)</p> Signup and view all the answers

What is the oxidation state of the heme group in Cyt C after donating an electron to Complex IV?

<p>Fe3+ (D)</p> Signup and view all the answers

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