Cystic Fibrosis: Aetiology and Genetics
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Questions and Answers

What is the primary cause of cystic fibrosis?

  • A dysfunction in the CFTR protein (correct)
  • An autosomal recessive gene
  • A genetic mutation in the pancreas
  • A viral infection in the lungs
  • Which organ system is primarily affected by the thick, sticky secretions in cystic fibrosis?

  • The cardiovascular system
  • The respiratory system (correct)
  • The nervous system
  • The digestive system
  • What is the probability that a child will be born with cystic fibrosis if both parents are carriers of the CF gene?

  • 1 in 25
  • 1 in 10
  • 1 in 4 (correct)
  • 1 in 2
  • What is the primary reason for the impaired mucociliary clearance in the airways of individuals with cystic fibrosis?

    <p>Dehydration of the airway surface</p> Signup and view all the answers

    What is the current status of a cure for cystic fibrosis?

    <p>There is no cure, but treatments are available</p> Signup and view all the answers

    What is the approximate percentage of individuals who are carriers of the cystic fibrosis gene?

    <p>1 in 25</p> Signup and view all the answers

    Which of the following is NOT a potential complication or co-morbidity associated with cystic fibrosis?

    <p>Chronic obstructive pulmonary disease (COPD)</p> Signup and view all the answers

    What is the primary method for diagnosing cystic fibrosis in newborns?

    <p>Newborn screening followed by a sweat test</p> Signup and view all the answers

    Which of the following statements about CFTR modulator therapy is NOT true?

    <p>It is a cure for cystic fibrosis</p> Signup and view all the answers

    What is the primary reason for the dramatic increase in life expectancy for individuals with cystic fibrosis over the past few decades?

    <p>Improved understanding of the disease, screening, and specialist care</p> Signup and view all the answers

    Which of the following statements about the diagnosis of cystic fibrosis is true?

    <p>It is often suspected based on clinical symptoms alone</p> Signup and view all the answers

    Which of the following statements about the impact of cystic fibrosis is NOT true?

    <p>It is primarily a disease of the respiratory system</p> Signup and view all the answers

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