Podcast
Questions and Answers
Which statement about receptor enzymes is correct?
Which statement about receptor enzymes is correct?
- They contain an enzyme activity that acts on a cytosolic substrate (correct)
- They have a ligand-binding site on the cytosolic side of the membrane
- They are not usually membrane-associated proteins
- They contain an enzyme activity that acts on the extracellular ligand
Which enzyme activity do receptor enzymes possess?
Which enzyme activity do receptor enzymes possess?
- GTPase activity that acts on the cytosolic side (correct)
- Ligase activity that acts on the cell membrane
- Kinase activity that acts on the extracellular ligand
- Phosphatase activity that acts on the intracellular domain
What is the main function of cholera toxins?
What is the main function of cholera toxins?
- Stimulate the phosphatase activity of FGFR
- Activate the GTPase activity of Gs
- Enhance the kinase activity of TrkA
- Inhibit the GTPase activity of Gi (correct)
Which process does dimerization of receptors upon ligand binding lead to?
Which process does dimerization of receptors upon ligand binding lead to?
What is the role of adaptor proteins in signal transduction?
What is the role of adaptor proteins in signal transduction?
What is the primary function of stimulatory G protein (Gs) in signal transduction?
What is the primary function of stimulatory G protein (Gs) in signal transduction?
What is the role of inhibitory G protein (Gi) in the G protein signaling pathway?
What is the role of inhibitory G protein (Gi) in the G protein signaling pathway?
What is a key function of the GTPase activity of G proteins?
What is a key function of the GTPase activity of G proteins?
How does desensitization of the β-adrenergic receptor contribute to cellular signaling?
How does desensitization of the β-adrenergic receptor contribute to cellular signaling?
Which of the following proteins play a crucial role in bridging activated receptors to downstream signaling pathways in cell signaling?
Which of the following proteins play a crucial role in bridging activated receptors to downstream signaling pathways in cell signaling?
What is the primary function of effector enzymes in the plasma membrane in the context of cellular signaling?
What is the primary function of effector enzymes in the plasma membrane in the context of cellular signaling?
What is the role of cyclic nucleotide phosphodiesterase in the cAMP signaling pathway?
What is the role of cyclic nucleotide phosphodiesterase in the cAMP signaling pathway?
How does somatostatin affect the activity of adenylyl cyclase?
How does somatostatin affect the activity of adenylyl cyclase?
What is the function of GTPase activator proteins (GAPs) in the regulation of G protein activity?
What is the function of GTPase activator proteins (GAPs) in the regulation of G protein activity?
What is the role of β-arrestin in the desensitization of the β-adrenergic receptor?
What is the role of β-arrestin in the desensitization of the β-adrenergic receptor?
What is the function of adaptor proteins in cell signaling?
What is the function of adaptor proteins in cell signaling?
What is the effect of activating mutations in Gα on the concentration of cAMP in the cell?
What is the effect of activating mutations in Gα on the concentration of cAMP in the cell?
What is the effect of cholera toxin on the activity of Gsα?
What is the effect of cholera toxin on the activity of Gsα?
What is the effect of GTP hydrolysis on the conformation of Ras?
What is the effect of GTP hydrolysis on the conformation of Ras?
What is the effect of defects in the G protein Ras on cell division?
What is the effect of defects in the G protein Ras on cell division?
What is the effect of Gq-coupled receptors on the activity of phospholipase C?
What is the effect of Gq-coupled receptors on the activity of phospholipase C?
