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Questions and Answers

What should a purchaser do immediately after buying the notes?

  • Print the notes to hard copy
  • Begin studying the notes online
  • Download and save the files (correct)
  • Share the notes with classmates
  • What is one of the prohibitions regarding the notes?

  • Sharing the notes with friends (correct)
  • Saving the notes to external hard drives
  • Viewing the notes on multiple devices
  • Printing the notes for personal use
  • How many devices can a user view the files on simultaneously?

  • 1
  • 3
  • 2 (correct)
  • Unlimited
  • What is recommended for backing up the notes?

    <p>Save to an external hard drive</p> Signup and view all the answers

    What happens if a customer attempts to share or distribute the notes?

    <p>Access will be revoked and files locked</p> Signup and view all the answers

    After saving the notes, what is not necessary for users?

    <p>To re-download the notes</p> Signup and view all the answers

    What is the goal of the notes according to the message from the team?

    <p>To streamline learning for all medical students</p> Signup and view all the answers

    What is NOT permitted under the license agreement of the notes?

    <p>Sharing notes with other students</p> Signup and view all the answers

    What is the primary function of the fibrous pericardium?

    <p>Anchors the heart to surrounding structures</p> Signup and view all the answers

    Which layer of the heart wall is responsible for the contraction of the heart?

    <p>Myocardium</p> Signup and view all the answers

    What is the role of the endocardium in the heart?

    <p>Lines the chambers and prevents blood clotting</p> Signup and view all the answers

    Where is the middle mediastinum located?

    <p>In the inferior mediastinum behind the sternum</p> Signup and view all the answers

    What structure surrounds the heart and contains serous fluid?

    <p>Pericardium</p> Signup and view all the answers

    Which part of the fibrous skeleton of the heart serves to electrically isolate the heart's chambers?

    <p>Septums</p> Signup and view all the answers

    Which of the following correctly describes the serous pericardium?

    <p>It has parietal and visceral layers</p> Signup and view all the answers

    What is the primary material that reinforces the myocardium and supports the heart's structure?

    <p>Connective tissue fibers</p> Signup and view all the answers

    What is the primary effect of the parasympathetic nervous system on heart rate?

    <p>Decreases heart rate through acetylcholine release</p> Signup and view all the answers

    How does sympathetic stimulation affect the heart muscle cells?

    <p>Enhances contractile force due to increased calcium influx</p> Signup and view all the answers

    What does a typical 12-lead ECG measure?

    <p>A combination of electrical signals over time</p> Signup and view all the answers

    Which of the following statements about the sympathetic nervous system is true?

    <p>It raises heart rate and increases calcium permeability in heart tissues</p> Signup and view all the answers

    What initiates the cyclic AMP pathway in the sympathetic nervous system?

    <p>Binding of norepinephrine to beta 1 receptors</p> Signup and view all the answers

    What effect does the parasympathetic nervous system have on potassium permeability in the heart?

    <p>Increases potassium efflux, hyperpolarizing the cell</p> Signup and view all the answers

    Which of the following correctly describes the role of acetylcholine in heart function?

    <p>It helps to hyperpolarize the SA and AV nodes, slowing the heart rate</p> Signup and view all the answers

    How does increased sodium permeability affect the heart rate during sympathetic stimulation?

    <p>Increases depolarization speed, raising heart rate</p> Signup and view all the answers

    What structure allows action potentials to move from cell to cell in the heart?

    <p>Gap junctions</p> Signup and view all the answers

    What is the correct sequence of the heart's conduction system?

    <p>SA Node → AV Node → Bundle of His → R &amp; L Bundle Branches → Purkinje Fibres</p> Signup and view all the answers

    Which ions are primarily involved in the spontaneous depolarization of the SA and AV node cells?

    <p>Na+ and Ca2+</p> Signup and view all the answers

    During repolarization of pacemaker cells, which ion channels primarily open?

    <p>K+ channels</p> Signup and view all the answers

    What type of action potentials do contractile cardiac cells generate?

    <p>Fast Non-Pacemaker Type</p> Signup and view all the answers

    What initiates the massive influx of Na+ ions in contractile cardiac cells?

    <p>Threshold reached</p> Signup and view all the answers

    What causes the plateau phase in the action potential of contractile cardiac cells?

    <p>Inactivation of Na+ channels</p> Signup and view all the answers

    Which factor primarily determines the firing frequency of SA and AV node cells?

    <p>Movement of Na+ ions</p> Signup and view all the answers

    What is the role of the Na/K-ATPase during repolarization?

    <p>It removes excess Na+ and replaces deficit K+ in the cell.</p> Signup and view all the answers

    What is the approximate duration of the Absolute Refractory Period in cardiac muscle?

    <p>200ms</p> Signup and view all the answers

    What happens to K+ channels during repolarization of cardiac muscle cells?

    <p>They open, accelerating the process of repolarization.</p> Signup and view all the answers

    Which structure sets the pace for the heart's contractions?

    <p>The SinoAtrial (SA) Node</p> Signup and view all the answers

    What effect does the Parasympathetic Nervous System have on heart rate?

    <p>It lowers heart rate to maintain a normal resting rate.</p> Signup and view all the answers

    Where is the Atrioventricular (AV) Node located?

    <p>Inferior portion of the InterAtrial Septum.</p> Signup and view all the answers

    What indicates that the SA Node is functioning properly?

    <p>Presence of the P-Wave</p> Signup and view all the answers

    How does the influx of Ca+ ions contribute to muscle contraction in cardiac muscle cells?

    <p>By facilitating muscular contraction through increased myoplasmic Ca+ levels.</p> Signup and view all the answers

    What does the PR-Segment reflect in the ECG?

    <p>Delay between the SA Node and AV Node</p> Signup and view all the answers

    What occurs during the Relative Refractory Period?

    <p>The muscle can respond to stronger-than-normal stimuli.</p> Signup and view all the answers

    What causes the Q-Wave to show a biphasic trace?

    <p>Signal cancellation by atrial repolarization</p> Signup and view all the answers

    Which part of the ECG waveform corresponds to ventricular depolarization?

    <p>R-Wave</p> Signup and view all the answers

    What occurs during the ST-Segment of the ECG?

    <p>Ventricular contraction</p> Signup and view all the answers

    Which wave in the ECG indicates repolarization of the ventricles?

    <p>T-Wave</p> Signup and view all the answers

    Which wave is associated with depolarization of the interventricular septum?

    <p>Q-Wave</p> Signup and view all the answers

    In which situation is a negative deflection observed in the ECG?

    <p>When depolarization moves away from a positive electrode</p> Signup and view all the answers

    Study Notes

    Cardiovascular System Final Edition Notes

    • This document is a pre-summarized, ready-to-study, high-yield set of notes on anatomy, physiology, and pathology of the cardiovascular system.
    • The book is 201 pages in length.
    • It provides open-source images and/or attributions where possible.
    • Notes are for a time-poor student of medicine, pre-med, USMLE, or PA students.

    Using the Notes

    • Purchase immediately and download, as download access is not permanent.
    • Sharing of notes is strictly prohibited.
    • Users are permitted to download/save/view files on up-to 2 simultaneous devices.
    • Documents may be printed to hard copy for backup.
    • The same email address should be used for any future purchases for file visibility.
    • A download allowance is allocated per order, extensions may be required.
    • The user may use the discount code "TAKE20OFF" for 20% off future purchases.
    • Instructions for upgrading to a bundle deal with a 80% discount are available online.

    Table of Contents

    • Anatomy & Physiology Notes:
      • Anatomy of the heart
      • Electrophysiology of the heart
      • ECG Physiology
      • Mechanical events of the cardiac cycle
      • Cardiodynamics
      • Haemodynamics
      • Blood pressure physiology
      • Anatomy & physiology of blood vessels
      • Physiology of hypertension
      • Physiology of shock
      • Physiology of myocardial ischaemia / ischaemia
      • Effects of aging on the heart
    • Pathology Notes:
      • Congenital heart defects
      • Aneurysms & Dissections
      • Arrhythmias
      • Dyslipidaemia
      • Atherosclerosis
      • Drug classes for treating arrhythmias
      • Ischemic heart disease
      • Acute cardiogenic pulmonary oedema
      • Heart failure
      • Pathologies of “Heart Muscle Diseases”
      • Pathology of hypertension
      • Pathology of shock
      • DVT & PE
      • Carcinoid heart disease
      • Infective & non-infective endocarditis
      • Lymphangitis
      • Myocarditis – viral & toxic
      • Pericarditis
      • Pericardial effusion
      • Acute arterial occlusion (“critical limb ischaemia”)
      • Peripheral vascular disease
      • Varicose veins
      • Chronic skin ulcers
      • Tumours of vessels
      • Important vasculitis
      • Kaposi sarcoma
      • Buerger's Disease ("thromboangiitis obliterans")

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