16 Questions
What is the blood pressure range that is considered a 'silent killer'?
130–139/85-89 mmHg
What is the first step in finding the source of excess cortisol production in Cushing's Syndrome?
Perform an overnight low dose dexamethasone suppression test
What is the typical ACTH level in ectopic ACTH production?
Highly elevated
What is the approximate surgical cure rate for Cushing's Disease?
65-90%
What is the percentage of Cushing's Disease cases caused by pituitary adenoma?
80-85%
Which of the following medications can cause analytical interference with chromogranin A?
Labetalol
What is the primary mechanism of action of mineralocorticoids like aldosterone?
Activation of the epithelial sodium channel
Which of the following is NOT a secondary cause of hypertension with an endocrine origin?
Hypothyroidism
What is the purpose of measuring 24-hour urine cortisol levels?
To diagnose Cushing's syndrome
According to the Seventh Report of the Joint National Committee, what is the primary goal of hypertension treatment?
Reducing blood pressure to normal levels
Which of the following is NOT a characteristic of Apparent Mineralocorticoid Excess?
Increased aldosterone
What is the primary effect of AT II on the distal renal tubules?
Stimulates sodium reabsorption
Which of the following tests is used to diagnose ectopic ACTH production?
CRH stimulation test
What is the primary effect of Amiloride on the body?
Blocks the epithelial sodium channel (ENaC)
What is the characteristic of a patient with a defect in 11β-hydroxysteroid dehydrogenase type II (11HSD type II)?
Hypertension and hypokalemia
Which of the following is a characteristic of Phaeochromocytoma?
Paroxysmal or sustained hypertension
This quiz covers the endocrine causes of hypertension, specifically Cushing's Syndrome, including diagnosis and symptoms such as loss of diurnal rhythm and low dose dexamethasone suppression test. It's designed for Semester 5 students.
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