Cushing's Disease and Addison's Disease

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Questions and Answers

Which of the following is NOT a characteristic of Cushing's Disease?

  • May be caused by adrenal cortical adenoma
  • Excess secretion of glucocorticoids
  • Hirsutism or virilization present
  • Excessive production of mineralocorticoids (correct)

In Addison's Disease, what is the primary cause of the failure of secretion of adrenal cortical hormones?

  • Tuberculosis
  • Adrenal cortical adenoma
  • Autoimmune adrenalitis (correct)
  • Adrenal cortical carcinoma

What distinguishes Ectopic ACTH Syndrome from Cushing's Disease?

  • Tumor elsewhere in the body secreting ACTH-like substance (correct)
  • Excessive secretion of glucocorticoids
  • Presence of androgens and hirsutism
  • Stimulation by zona fasciculata to produce glucocorticoids

What is the most likely cause of Cushing's disease?

<p>Increase in the amount of glucocorticoids in the body (A)</p> Signup and view all the answers

What are the clinical features associated with Cushing's disease?

<p>Moon facies and hypertension (C)</p> Signup and view all the answers

What is the role of the adrenal medulla in Cushing's disease?

<p>Secretes glucocorticoids under direct control of the sympathetic nervous system (C)</p> Signup and view all the answers

Which hormone is primarily responsible for the symptoms seen in Cushing's Disease?

<p>Cortisol (C)</p> Signup and view all the answers

In which condition does the excess ACTH stimulate the adrenals to increase corticosteroids production?

<p>Cushing's Disease (B)</p> Signup and view all the answers

What is the primary cause of Addison's Disease?

<p>Autoimmune destruction of the adrenal glands (B)</p> Signup and view all the answers

Which of the following conditions is most likely to result from panhypopituitarism?

<p>Addison's Disease (A)</p> Signup and view all the answers

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