6 Questions
What percentage of CSF is produced by the choroid plexuses?
95%
At what rate is CSF produced?
0.3ml/min
What is the total volume of CSF in the body?
150ml
Which foramen does CSF leave the ventricular system through?
All of the above
Where is CSF primarily absorbed?
Arachnoid villi
What is the function of arachnoid villi?
Absorbing CSF
Study Notes
CSF Production and Circulation
- 95% of CSF is produced by the choroid plexuses in the lateral ventricles and 4th ventricle, with a small amount produced by the ependymal lining of the ventricles.
- CSF production rate: 0.3 ml/min, which is equivalent to 450 ml/24h.
- The total volume of CSF is 150 ml, and it is turned over 3 times every day.
CSF Pathway
- CSF is produced in the lateral, 3rd, and 4th ventricles by the choroid plexus.
- CSF travels from the lateral ventricles through the interventricular foramina of Monro to the 3rd ventricle, then through the cerebral aqueduct of Sylvius to the 4th ventricle.
- CSF leaves the ventricular system at the 4th ventricle through the midline foramen of Magendie and the two lateral foramina of Luschka.
- CSF enters the subarachnoid spaces, circulating to the surface of the brain and spinal cord.
CSF Absorption
- CSF is absorbed primarily by arachnoid villi (granulation) that extend into the dural venous sinuses.
- Arachnoid villi act as unidirectional valves, allowing CSF to leave the subarachnoid space and enter the venous sinuses.
Learn about the production and circulation of cerebrospinal fluid (CSF) in the brain, including the rate of CSF production, total CSF volume, and CSF pathway. Understand how CSF is produced and travels through the ventricles.
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