Crystalline and Amorphous Solids

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Questions and Answers

Which factor does not influence polymorphism?

  • Pressure
  • Solvents
  • Humidity (correct)
  • Temperature

What is the key characteristic of enantiotropic polymorphs?

  • Affected by temperature and moisture (correct)
  • Reversible change
  • Not affected by grinding
  • Irreversible change

Which type of polymorph undergoes an irreversible change?

  • Monotropic (correct)
  • Stable
  • Metastable
  • Enantiotropic

What can cause crystal growth in creams due to phase transformation?

<p>Temperature changes (A)</p> Signup and view all the answers

Which factor is critical in causing eventual caking in suspensions?

<p>Crystal size (D)</p> Signup and view all the answers

What effect can surfactants have on crystal growth?

<p>Accelerate crystal growth (B)</p> Signup and view all the answers

Which type of polymorph is not affected by temperature and moisture?

<p>Monotropic (B)</p> Signup and view all the answers

In which form may some polymorphs be difficult to inject or formulate as tablets?

<p>'Metastable' form (C)</p> Signup and view all the answers

Which factor influences crystal growth by adsorbing onto the growing faces?

<p>Solvents (B)</p> Signup and view all the answers

What type of polymorph undergoes irreversible change and is unaffected by temperature, moisture, and grinding?

<p>Monotropic Stable (D)</p> Signup and view all the answers

Which type of polymorph undergoes reversible changes affected by temperature, moisture, and grinding?

<p>Enantiotropic Stable (C)</p> Signup and view all the answers

Which factor does NOT influence polymorphism?

<p>Pressure (B)</p> Signup and view all the answers

What pharmaceutical implication does polymorphism have regarding cream formulations?

<p>Resulting in gritty creams due to phase transformation (A)</p> Signup and view all the answers

Which stable polymorph is affected by temperature, moisture, and grinding?

<p>Enantiotropic Stable (A)</p> Signup and view all the answers

Which type of polymorph undergoes irreversible change and is affected by temperature, moisture, and grinding?

<p>Monotropic Metastable (D)</p> Signup and view all the answers

Which factor plays a critical role in causing eventual caking in suspensions?

<p>Rate of Crystallization (A)</p> Signup and view all the answers

Which factor is listed as influencing polymorphism?

<p>Agitation (C)</p> Signup and view all the answers

What type of polymorph undergoes irreversible change and is not influenced by temperature, moisture, or grinding?

<p>Enantiotropic Metastable (B)</p> Signup and view all the answers

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