18 Questions
Which factor does not influence polymorphism?
Humidity
What is the key characteristic of enantiotropic polymorphs?
Affected by temperature and moisture
Which type of polymorph undergoes an irreversible change?
Monotropic
What can cause crystal growth in creams due to phase transformation?
Temperature changes
Which factor is critical in causing eventual caking in suspensions?
Crystal size
What effect can surfactants have on crystal growth?
Accelerate crystal growth
Which type of polymorph is not affected by temperature and moisture?
Monotropic
In which form may some polymorphs be difficult to inject or formulate as tablets?
'Metastable' form
Which factor influences crystal growth by adsorbing onto the growing faces?
Solvents
What type of polymorph undergoes irreversible change and is unaffected by temperature, moisture, and grinding?
Monotropic Stable
Which type of polymorph undergoes reversible changes affected by temperature, moisture, and grinding?
Enantiotropic Stable
Which factor does NOT influence polymorphism?
Pressure
What pharmaceutical implication does polymorphism have regarding cream formulations?
Resulting in gritty creams due to phase transformation
Which stable polymorph is affected by temperature, moisture, and grinding?
Enantiotropic Stable
Which type of polymorph undergoes irreversible change and is affected by temperature, moisture, and grinding?
Monotropic Metastable
Which factor plays a critical role in causing eventual caking in suspensions?
Rate of Crystallization
Which factor is listed as influencing polymorphism?
Agitation
What type of polymorph undergoes irreversible change and is not influenced by temperature, moisture, or grinding?
Enantiotropic Metastable
Learn about the differences between crystalline and amorphous solids, including their structural arrangements, melting points, and examples. Understand the concepts of critical pressure and critical temperature.
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