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What is the main purpose of dendrites in a neuron?
What is the main purpose of dendrites in a neuron?
The resting potential of a neuron is positive due to the high concentration of sodium ions inside the cell.
The resting potential of a neuron is positive due to the high concentration of sodium ions inside the cell.
False
What are the two types of ion pumps involved in establishing the resting potential of a neuron?
What are the two types of ion pumps involved in establishing the resting potential of a neuron?
Sodium and potassium pumps
Neurotransmitters are released from the ______ membrane.
Neurotransmitters are released from the ______ membrane.
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Match the type of nerve fiber with its characteristics:
Match the type of nerve fiber with its characteristics:
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How do nerve impulses (action potentials) propagate along a neuron?
How do nerve impulses (action potentials) propagate along a neuron?
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A signal can pass in both directions at a typical synapse.
A signal can pass in both directions at a typical synapse.
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What role does calcium play in neurotransmitter release?
What role does calcium play in neurotransmitter release?
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What is the typical resting potential of a neuron?
What is the typical resting potential of a neuron?
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Neurons transmit information primarily through chemical signals.
Neurons transmit information primarily through chemical signals.
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What are the primary ions involved in generating a nerve impulse?
What are the primary ions involved in generating a nerve impulse?
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The change in potential difference across a neuron during an impulse is known as __________.
The change in potential difference across a neuron during an impulse is known as __________.
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Match the following terms with their definitions:
Match the following terms with their definitions:
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What happens during the depolarization phase of an action potential?
What happens during the depolarization phase of an action potential?
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The cytoplasm of a neuron is located in its cell body.
The cytoplasm of a neuron is located in its cell body.
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What is the role of the membrane potential in neurons?
What is the role of the membrane potential in neurons?
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What is the primary role of sodium-potassium pumps in neurons?
What is the primary role of sodium-potassium pumps in neurons?
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Three potassium ions are pumped into the neuron for every two sodium ions pumped out.
Three potassium ions are pumped into the neuron for every two sodium ions pumped out.
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What charge is the membrane potential of a neuron at rest approximately?
What charge is the membrane potential of a neuron at rest approximately?
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The leakage of _______ ions contributes to the imbalance of ions across the membrane.
The leakage of _______ ions contributes to the imbalance of ions across the membrane.
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Match the ion with its movement direction in the sodium-potassium pump:
Match the ion with its movement direction in the sodium-potassium pump:
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Which factor does NOT contribute to the resting potential?
Which factor does NOT contribute to the resting potential?
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Ion movement across the membrane occurs through active transport only.
Ion movement across the membrane occurs through active transport only.
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What type of transport is used by sodium-potassium pumps?
What type of transport is used by sodium-potassium pumps?
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What causes the depolarization of the axon membrane?
What causes the depolarization of the axon membrane?
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Repolarization of the axon membrane makes its charge positive.
Repolarization of the axon membrane makes its charge positive.
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What is the normal resting membrane potential of a neuron in millivolts?
What is the normal resting membrane potential of a neuron in millivolts?
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The lipid-rich substance that surrounds nerve fibres is known as _____.
The lipid-rich substance that surrounds nerve fibres is known as _____.
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Which adaptation helps squid increase the speed of nerve impulses?
Which adaptation helps squid increase the speed of nerve impulses?
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Nerve impulses travel at about 100 m/s in humans due to large diameter axons.
Nerve impulses travel at about 100 m/s in humans due to large diameter axons.
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What is the role of Schwann cells in relation to axons?
What is the role of Schwann cells in relation to axons?
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What is the effect of the myelin sheath on the speed of nerve impulse transmission?
What is the effect of the myelin sheath on the speed of nerve impulse transmission?
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Saltatory conduction refers to the continuous transmission of an action potential along a myelinated fiber.
Saltatory conduction refers to the continuous transmission of an action potential along a myelinated fiber.
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What tiny gap exists between the pre-synaptic neuron and the post-synaptic neuron?
What tiny gap exists between the pre-synaptic neuron and the post-synaptic neuron?
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In myelinated fibers, action potentials '_______' from node to node.
In myelinated fibers, action potentials '_______' from node to node.
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Match the type of synapse with its description:
Match the type of synapse with its description:
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At which locations are the axon membranes exposed in myelinated fibers?
At which locations are the axon membranes exposed in myelinated fibers?
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Myelination has little benefit for very small axon diameters.
Myelination has little benefit for very small axon diameters.
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What is the primary function of synapses?
What is the primary function of synapses?
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What is the primary role of neurotransmitters?
What is the primary role of neurotransmitters?
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The influx of calcium ions (Ca2+) into a neuron triggers the release of neurotransmitters.
The influx of calcium ions (Ca2+) into a neuron triggers the release of neurotransmitters.
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What happens to the postsynaptic membrane when neurotransmitters bind to neuroreceptors?
What happens to the postsynaptic membrane when neurotransmitters bind to neuroreceptors?
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Neurotransmitters are made in the _____ apparatus of the pre-synaptic neuron.
Neurotransmitters are made in the _____ apparatus of the pre-synaptic neuron.
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Match the neurotransmitter with its common function:
Match the neurotransmitter with its common function:
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Which ion influx is responsible for initiating an excitatory action potential?
Which ion influx is responsible for initiating an excitatory action potential?
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An action potential can cross the synaptic cleft directly from one neuron to another.
An action potential can cross the synaptic cleft directly from one neuron to another.
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The pre-synaptic neuron releases neurotransmitters via _____ that fuse with the membrane.
The pre-synaptic neuron releases neurotransmitters via _____ that fuse with the membrane.
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Study Notes
Neural Signaling
- Neurons are nerve cells within the nervous system that carry electrical impulses.
- The nervous system uses neurons to communicate internally.
- Neurons have a cell body containing cytoplasm and a nucleus.
- Neurons have a long, single axon and multiple shorter dendrites extending from the cell body.
- Electrical impulses travel along these fibres.
- ATP provides energy for pumping sodium and potassium ions in opposite directions across the neuron's plasma membrane.
- The concept of a membrane potential or polarization is crucial for neuronal signaling.
- Neurons have a resting potential that is negative.
- Electrochemical gradients are maintained through the pumping of ions.
Nerve Impulses as Action Potentials
- Nerve impulses are action potentials that are propagated along nerve fibers.
- Positively charged ions move during nerve impulses.
- The speed of nerve impulses varies dependent on the presence or absence of myelination.
- Myelination increases the speed of nerve impulse transmission.
- The transmission speed varies depending on fiber diameter.
- Larger fibers conduct impulses faster.
- Chemical synapses (also called synapses) are connections where signaling occurs.
- Signals pass in one direction across synapses.
- Calcium uptake depolarizes a presynaptic membrane and activates neurotransmitters.
- Neurotransmitters diffuse across the synaptic gap.
Synapses as Junctions Between Neurons
- A synapse connects the end of one neuron to another neuron or effector cell.
- Axons (part of pre-synaptic neuron) and dendrites (part of post-synaptic neuron) create synaptic contacts.
- These junctions have a gap called a synaptic cleft.
- Neurotransmitters are chemical messengers that carry the nerve impulse across the synapse.
- Neurotransmitters are released from the pre-synaptic neuron, which is the sending neuron.
- Neurotransmitters bind to receptors on the post-synaptic neuron, which is the receiving neuron, causing a response.
- Some other types of synapses include synapses between neurons and muscle fibers (neuromuscular synapses), and synapses between neurons and glands (neuroglandular synapses).
- Sensory receptors act in some synapses, like those in the skin.
Generation of the Resting Potential
- A nerve impulse, driven by changes in sodium and potassium ion concentration, creates a resting potential in neurons (approximately -70 mV).
- The unequal distribution of ions across the membrane creates a negative charge inside the neuron.
- Membrane potential develops due to the sodium-potassium pump, ion leakage, and negatively charged proteins within the cytoplasm.
- The sodium-potassium pump moves three sodium ions out of the cell and two potassium ions into the cell.
- The membrane is more permeable to potassium, leading to potassium leakage out of the cell.
Variation in the Speed of Nerve Impulses
- Larger axon diameters lead to faster conduction of nerve impulses.
- Myelination increases the speed of impulse transmission (saltatory conduction).
- The myelin sheath is an insulating layer around the axon that prevents ion leakage.
- Impulses "jump" between gaps (nodes of Ranvier) in the myelin sheath.
- Factors like axon diameter increase and myelination increase the conduction speeds.
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