Crohn's Disease Complications and Diagnosis
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Questions and Answers

Which of the following complications of Crohn's disease directly impacts the digestive system?

  • Skin lesions
  • Thromboembolism
  • Strictures (correct)
  • Ankylosing spondylitis
  • What is a potential consequence of Crohn's disease affecting the small intestine?

  • Increased risk of kidney stones
  • Decreased iron absorption (correct)
  • Formation of gallstones
  • Increased production of digestive enzymes
  • Which of these findings on a stool culture would support a diagnosis of Crohn's disease?

  • Presence of normal bacteria
  • Absence of parasites
  • Presence of bacteria causing food poisoning
  • Presence of blood and mucus (correct)
  • What imaging study can demonstrate an "apple core" appearance in the area of a stricture in a patient with Crohn's disease?

    <p>Barium studies (B)</p> Signup and view all the answers

    Which of the following is NOT a common symptom of Crohn's disease?

    <p>Constipation (A)</p> Signup and view all the answers

    Which of the following blood test results would likely be elevated in a patient with Crohn's disease?

    <p>White blood cell count (D)</p> Signup and view all the answers

    Which of the following complications of Crohn's disease is MOST likely to directly lead to anemia?

    <p>Malabsorption (B)</p> Signup and view all the answers

    What is a potential consequence of Crohn's disease that could affect a patient's musculoskeletal system?

    <p>Ankylosing spondylitis (A)</p> Signup and view all the answers

    Which of the following clinical findings, besides symptoms like diarrhea and abdominal pain, would be MOST suggestive of Crohn's disease over other inflammatory bowel diseases?

    <p>Rectal bleeding (A)</p> Signup and view all the answers

    Which of the following diagnostic procedures should be avoided if bowel perforation is suspected in a patient with Crohn's disease?

    <p>Barium studies (C)</p> Signup and view all the answers

    Which drug therapy approach involves utilizing less toxic medications initially and gradually escalating to stronger options as needed for treatment?

    <p>Step-Up Approach (C)</p> Signup and view all the answers

    What is the primary mechanism of action for aminosalicylates in treating Crohn's disease?

    <p>Inhibiting the production of inflammatory mediators (D)</p> Signup and view all the answers

    Which of these drugs is NOT categorized as an immunosuppressant used in Crohn's disease management?

    <p>Budesonide (Entocort) (D)</p> Signup and view all the answers

    Which specific type of surgical intervention aims to widen narrowed areas of the bowel in Crohn's disease patients?

    <p>Strictureplasty (C)</p> Signup and view all the answers

    Which of the following is NOT a key focus of nutritional therapy in Crohn's disease management?

    <p>Promoting weight gain (D)</p> Signup and view all the answers

    What dietary approach emphasizes the use of easily digestible nutrients and avoids fiber-rich foods in Crohn's disease?

    <p>Elemental diet (A)</p> Signup and view all the answers

    Which of the following is NOT a common nursing assessment component for Crohn's disease patients?

    <p>Blood pressure (B)</p> Signup and view all the answers

    Which of these instructions is LEAST likely to be included in patient teaching for Crohn's disease management?

    <p>Strategies for managing insomnia (C)</p> Signup and view all the answers

    Which of the following statements is TRUE about ulcerative colitis?

    <p>It involves inflammation of the mucosal layer of the large intestine. (A)</p> Signup and view all the answers

    In the context of Crohn's disease, which of these medications is most effective in reducing inflammation?

    <p>Corticosteroids (B)</p> Signup and view all the answers

    Which of the following is a defining characteristic of Crohn's disease, differentiating it from other inflammatory bowel conditions?

    <p>The presence of skip lesions along the gastrointestinal tract. (C)</p> Signup and view all the answers

    In the context of the etiology of Crohn's disease, which statement correctly identifies the known factors?

    <p>The cause is unknown, but a genetic predisposition is believed to have a role. (D)</p> Signup and view all the answers

    Which pathological feature is commonly observed in Crohn's disease that contributes to its complex presentation?

    <p>Deep, longitudinal ulcerations penetrating the bowel wall, leading to fistulas and strictures. (A)</p> Signup and view all the answers

    What is the most frequent location in the gastrointestinal tract where Crohn's disease manifests?

    <p>The Terminal ileum. (C)</p> Signup and view all the answers

    The 'cobblestone appearance' often found in Crohn's disease refers to which specific pathological change?

    <p>Edematous mucosa surrounding deep longitudinal ulcers. (B)</p> Signup and view all the answers

    Besides the gastrointestinal tract, which complications of Crohn's disease can extend to other areas of the body?

    <p>Fistulous tracts to the skin, bladder, rectum, or vagina can form. (B)</p> Signup and view all the answers

    What best describes the clinical course of Crohn's disease?

    <p>A disease characterized by periods of exacerbation and remission. (B)</p> Signup and view all the answers

    Which of the following best describes the impact of Crohn's disease on the bowel wall?

    <p>Affects the entire thickness of the bowel wall. (B)</p> Signup and view all the answers

    What is the expected output of an ileostomy patient in a 24-hour period?

    <p>1500 to 2000 mL (C)</p> Signup and view all the answers

    Which statement regarding self-care instructions for a patient with a new stoma indicates a misconception?

    <p>I should use harsh soaps to clean the stoma area. (A)</p> Signup and view all the answers

    For patients recovering from inflammatory bowel disease, which menu choice reflects appropriate dietary modifications?

    <p>Baked cod, baked sweet potato, and canned pears (D)</p> Signup and view all the answers

    What potential complication should be monitored in a patient with a new colostomy?

    <p>Dehydration (D)</p> Signup and view all the answers

    Which exercise is most beneficial for a patient to strengthen the pelvic floor muscles after ostomy surgery?

    <p>Kegel exercises (B)</p> Signup and view all the answers

    What is the primary symptom associated with ulcerative colitis?

    <p>Bloody diarrhea with mucus (B)</p> Signup and view all the answers

    Which complication is associated with severe cases of ulcerative colitis?

    <p>Hemorrhage (C)</p> Signup and view all the answers

    What surgery involves a total colectomy with rectal mucosal stripping and ileoanal reservoir?

    <p>Total colectomy with rectal mucosal stripping (A)</p> Signup and view all the answers

    Which of the following describes the characteristics of moderate diarrhea in ulcerative colitis?

    <p>10 stools per day with increased bleeding (C)</p> Signup and view all the answers

    Which systemic symptom is a recognized consequence of ulcerative colitis?

    <p>Anemia (A)</p> Signup and view all the answers

    What is a potential complication of the total protocolectomy with continent ileostomy?

    <p>Leakage (C)</p> Signup and view all the answers

    What is the maximum number of stools that can be experienced in severe ulcerative colitis?

    <p>10 to 20 stools per day (A)</p> Signup and view all the answers

    Which of the following is NOT a recognized extra-intestinal complication of ulcerative colitis?

    <p>Asthma (B)</p> Signup and view all the answers

    When does adaptation occur post-surgery in total colectomy with rectal mucosal stripping and ileoanal reservoir?

    <p>3 to 6 months (C)</p> Signup and view all the answers

    What is the main type of stool drainage following ileostomy?

    <p>Liquid (D)</p> Signup and view all the answers

    Study Notes

    Crohn's Disease/Ulcerative Colitis

    • Inflammatory bowel diseases (IBDs) affecting the gastrointestinal tract
    • Peak age of onset between teens and mid-30s, and a second peak around age 60
    • Equally affects both sexes
    • More common in individuals of Jewish and Middle European descent
    • Chronic disorder with periods of exacerbations (attacks) and remissions (periods of reduced symptoms)

    Crohn's Disease: Pathologic Characteristics

    • A non-continuous inflammatory disease
    • Can affect any point from the mouth to the anus
    • Characterized by "skip lesions" (inflammation occurring in sections of the GI Tract but not uniformly)
    • Affects the entire thickness of the bowel wall
    • Cobblestone appearance of the colonic mucosa
    • Granulomas and small bowel involvement are common features

    Crohn's Disease: Etiology and Pathophysiology

    • Ulcerations are deep and longitudinal (along the length of the bowel)
    • Ulcers penetrate between islands of inflamed edematous mucosa
    • This creates a classic cobblestone appearance
    • Narrowing of the lumen with stricture development can occur
    • Bowel obstruction is possible

    Crohn's Disease: Etiology and Pathophysiology

    • Microscopic leaks can allow bowel contents to spill into the peritoneal cavity, potentially leading to peritonitis
    • Abscesses or fistulas (abnormal passages) that connect with other loops of bowel, skin, bladder, rectum, or vagina can form

    Crohn's Disease: Clinical Manifestations

    • A chronic disorder with mild to severe exacerbations occurring unpredictably over years
    • Diarrhea and cramp-like abdominal pain are common complaints
    • Other symptoms can include bloody stool, fever, fatigue, weight loss and rectal bleeding

    Crohn's Disease: Complications

    • Intestinal: Fistulas, strictures, anal abscesses, perforation, recurrence after surgery, common at anastomoses (connection points in the GI Tract)
    • Extra-intestinal: Thromboembolism, arthritis, ankylosing spondylitis, eye inflammation, kidney stones, gallstones, and skin lesions

    Crohn's Disease: Complications

    • Nutritional problems are common due to small intestine involvement.
    • Common problems include fat malabsorption, anemia, electrolyte disturbances, and dehydration

    Crohn's Disease: Diagnostic Studies

    • History, physical examination, and blood tests (CBC, serum electrolyte levels, serum protein levels)
    • Stool cultures, stool tests, colonoscopy, flexible sigmoidoscopy, upper endoscopy, capsule endoscopy
    • CT scans and barium studies to visualize inflammation, abscess, strictures, and fistula formation

    Crohn's Disease: Collaborative Care - Drug Therapy

    • Step-up approach using less-toxic medications initially (aminosalicylates)
    • Step-down approach incorporating biologic (immunologic) and targeted therapies
    • Corticosteroids, immunosuppressants (azathioprine, 6-MP, MTX), and 5-aminosalicylates/sulfasalazine (e.g., azulfidine)
    • Antimicrobials are also used (e.g., metronidazole, ciprofloxacin)
    • Methylprednisone and budesonide (Entocort) are also commonly used

    Crohn's Disease: Collaborative Care - Immunosuppressants and Biologics

    • Immunosuppressants (with regular CBC monitoring) including methotrexate, and sometimes anti-TNF agents
    • Regular follow up needed for CBC monitoring in immunosuppressed patients.

    Crohn's Disease: Collaborative Care - Surgical Interventions

    • Strictureplasty procedures are used to widen areas of narrowed bowel
    • Complete bowel resection is required in severe cases
    • Other surgeries include procedures to correct complications (fistulas, abscesses, perforations) and anastomoses

    Crohn's Disease: Collaborative Care - Nutritional Therapy

    • Dietary consultation plays a key role in correcting and preventing malnutrition
    • Replacing fluid and electrolytes, preventing weight loss, and correcting high-calorie, high-protein diets are important
    • Avoiding low-residue foods is essential for many patients

    Crohn's Disease: Nursing Management

    • Assessing pain, autoimmune disorders, infection, fluid/electrolyte balance and presence of blood in diarrhea
    • Examining weight loss, anxiety, depression, use of prescribed medications, family history, and coping strategies
    • Teaching the patient about rest, diet, and perianal care, recognizing symptoms of recurrence, and knowing when to seek medical care

    Ulcerative Colitis: Clinical Manifestations

    • A chronic inflammatory disease of the large intestine
    • Typically involves the rectum and colon, with inflammation spreading into adjacent tissue
    • Ulcerations, fistulas, and abscess formation can occur
    • Bloody diarrhea with mucous is the primary symptom, frequently associated with abdominal pain, fatigue, and weight loss.

    Ulcerative Colitis: Complications

    • Intestinal: Strictures, perforations, hemorrhage, toxic megacolon, carcinoma, and Clostridium difficile infection
    • Extra-intestinal: Thromboembolism, arthritis, ankylosing spondylitis, eye inflammation, kidney stones, gallstones, skin lesions

    Ulcerative Colitis: Collaborative Care - Surgical Interventions

    • Total colectomy with rectal mucosal stripping and ileoanal reservoir or pouch are procedures for treatment of ulcerative colitis
    • Other procedures might include total protocolectomy with a continent ileostomy

    Ulcerative Colitis and Crohn Disease - Nutritional Therapy and Discharge Instructions

    • Provide information to patients about dietary modifications to reduce symptoms
    • Instructions on stoma care, including changing appliances, monitoring skin, and cleaning techniques.

    Student Response Questions

    • Includes diet recommendations after colostomy surgery: fruits, vegetables, whole-grain breads, and poached eggs with rice.
    • Also includes assessment of patient knowledge regarding disease recurrence.
    • Also includes assessment of patient knowledge regarding stoma care.

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    Description

    This quiz explores various complications associated with Crohn's disease, their effects on the digestive system, and key diagnostic factors. Test your knowledge on imaging studies, stool cultures, and lab results relevant to Crohn's disease. Gain a better understanding of how Crohn's disease presents clinically and its impact on overall health.

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