Craniofacial Development Quiz

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Questions and Answers

What is the primitive stomatodeum?

  • A small bump on the developing face
  • A deep narrow depression in the developing face
  • A group of cells that will form the heart
  • A wide, shallow depression in the developing face (correct)

What separates the stomatodeum from the developing heart?

  • Branchial clefts
  • Pharyngeal pouches
  • Branchial arches (correct)
  • The buccopharyngeal membrane

How many branchial arches are there?

  • 4
  • There are 5 arches, but one of them disappears.
  • 6 (correct)
  • 5

What is the basic structure of each branchial arch?

<p>Cartilage, nerve, and artery (B)</p> Signup and view all the answers

What is the significance of the first pharyngeal arch?

<p>It forms the bones of the face (A)</p> Signup and view all the answers

What derives from the maxillary process of the first pharyngeal arch?

<p>The structures that constitute the maxilla and the palate (B)</p> Signup and view all the answers

Which cartilage is derived from the first pharyngeal arch?

<p>Meckel's cartilage (D)</p> Signup and view all the answers

Which muscle is derived from the second pharyngeal arch?

<p>Stylohyoid (D)</p> Signup and view all the answers

What is the primary location of the mesoderm at the end of gastrulation?

<p>Between the ectoderm and endoderm layers (A)</p> Signup and view all the answers

Which nerve is associated with the first pharyngeal arch?

<p>CNV trigeminal (B)</p> Signup and view all the answers

Which of the following tissues is derived from the endoderm germ layer?

<p>Gut (C)</p> Signup and view all the answers

What is the typical age range for surgically correcting a cleft palate?

<p>3-8 months (B)</p> Signup and view all the answers

Which pharyngeal arch is associated with the constrictors of pharynx?

<p>Fourth pharyngeal arch (A)</p> Signup and view all the answers

What is the correct sequence of germ layers from outermost to innermost at the end of gastrulation?

<p>Ectoderm, Mesoderm, Endoderm (D)</p> Signup and view all the answers

What is a characteristic feature of Mandibulofacial dystostosis (Treacher-Collins syndrome)?

<p>Underdeveloped facial bones and micrognathia (B)</p> Signup and view all the answers

Which of the following tissues is NOT derived from the mesoderm germ layer?

<p>Epidermis (C)</p> Signup and view all the answers

Which cartilage is derived from the third pharyngeal arch?

<p>Greater horns of hyoid (B)</p> Signup and view all the answers

What is often associated with cleft palate?

<p>Mandibulofacial dystostosis (Treacher-Collins syndrome) (B)</p> Signup and view all the answers

Which pharyngeal arch is associated with the intrinsic muscles of the larynx?

<p>Sixth pharyngeal arch (D)</p> Signup and view all the answers

What is a common feature of Acro-facial dysostosis?

<p>A prominent forehead (C)</p> Signup and view all the answers

How many germ layers are present in the embryo at the end of gastrulation?

<p>3 (A)</p> Signup and view all the answers

What is Hemifacial microsomia characterized by?

<p>Great variability in clinical manifestations (D)</p> Signup and view all the answers

What may be associated with Nager syndrome?

<p>Both A and B (C)</p> Signup and view all the answers

Which of the following cranial nerves innervates the sensory receptors in the 1st arch of the tongue?

<p>Cranial nerve V (A)</p> Signup and view all the answers

At which week of development does the distal tip of the tongue form?

<p>6 weeks (A)</p> Signup and view all the answers

Which of the following muscles is derived from the head mesoderm and innervated by the vagus nerve X?

<p>Palatoglossus muscle (D)</p> Signup and view all the answers

What is the term for the congenital anomaly where the tongue is tied to the floor of the mouth?

<p>Ankylogossia (B)</p> Signup and view all the answers

Which of the following structures is formed from the median tongue bud?

<p>Anterior 2/3 of the tongue (C)</p> Signup and view all the answers

Flashcards

Primitive Stomatodeum

A wide, shallow depression in the developing face.

Separation between stomatodeum and developing heart:

Branchial arches.

Number of Branchial Arches

6

Basic Structure of Branchial Arch

Cartilage, nerve, and artery.

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Significance of 1st Pharyngeal Arch

Forms the bones of the face.

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Derivatives of Maxillary Process

Structures that constitute the maxilla and the palate.

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Cartilage from 1st Pharyngeal Arch

Meckel's cartilage.

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Muscle from 2nd Pharyngeal Arch

Stylohyoid

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Primary Location of Mesoderm

Between the ectoderm and endoderm layers.

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Nerve Associated with 1st Arch

CNV trigeminal.

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Tissue Derived from Endoderm

Gut

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Age for Cleft Palate Correction

3-8 months

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Arch for Pharynx Constrictors

Fourth pharyngeal arch.

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Germ Layer Sequence

Ectoderm, Mesoderm, Endoderm

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Feature of Mandibulofacial Dystostosis

Underdeveloped facial bones and micrognathia

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Not Mesoderm Derived

Epidermis

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Cartilage from 3rd Arch

Greater horns of hyoid.

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Associated with Cleft Palate

Mandibulofacial dystostosis (Treacher-Collins syndrome)

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Arch for Larynx Muscles

Sixth pharyngeal arch.

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Feature of Acro-facial Dysostosis

A prominent forehead.

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Germ Layers at Gastrulation End

3

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Hemifacial Microsomia

Great variability in clinical manifestations.

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Associated with Nager Syndrome

Both A and B

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Nerve for 1st Arch Tongue

Cranial nerve V

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Tongue Tip Formation

6 weeks

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Head Mesoderm Muscle

Palatoglossus muscle

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Tongue Tied Condition

Ankylogossia

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Structure Formed From Median Tongue Bud

Anterior 2/3 of the tongue

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Study Notes

Pharyngeal Arches and Pouches

  • Form in the 4th and 5th weeks of development
  • 5 arches (1, 2, 3, 4, and 6) and 5 corresponding pouches
  • Each arch consists of a 'bar' of mesenchymal tissue, lined on the outside by ectoderm and inside by endoderm
  • Separated from each other by deep clefts on the outside and pouches on the inside

Branchial Arches Structure

  • Cartilage, nerve, and artery components
  • Ectoderm outside, mesenchyme in the middle, and endoderm inside
  • Each arch has its own cranial nerve

First Pharyngeal Arch

  • Gives origin to the bones of the two lower thirds of the face
  • Divided into maxillary and mandibular processes
  • Maxillary process forms the maxilla, premaxilla, zygomatic bone, and squamous part of the temporal bone
  • Innervated by cranial nerve V (trigeminal)

Tongue Development

  • Multiple origins: foramen cecum, median tongue bud, and posterior tongue buds
  • Innervated by multiple nerves: cranial nerve V (trigeminal), facial nerve VII, glossopharyngeal IX, and vagus nerve X
  • Muscles from occipital somites (hypoglossal nerve XII) and head mesoderm (vagus nerve X)

Pharyngeal Arch Cartilages

  • 1st arch: Meckel's cartilage (mandibular prominence)
  • 2nd arch: Reichert's or hyoid cartilage
  • 3rd arch: none
  • 4th arch: none
  • 6th arch: none

Pharyngeal Arch Muscles

  • 1st arch: muscles of mastication
  • 2nd arch: muscles of facial expression
  • 3rd arch: stylopharyngeus
  • 4th arch: constrictors of pharynx
  • 6th arch: intrinsic muscles of the larynx

Craniofacial Development

  • Derived from the three germ layers: ectoderm, mesoderm, and endoderm
  • Ectoderm forms epidermis and nervous system
  • Mesoderm forms skeleton, muscle, dermis, kidney, gonads, and blood
  • Endoderm forms gut, liver, lungs, thyroid, and pancreas

Pharyngeal Arch Defects

  • Cleft palate
  • Mandibulofacial dystostosis (Treacher-Collins syndrome)
  • Acro-facial dysostosis
  • Nager Syndrome
  • Hemifacial microsomia (oto-mandibular syndrome)

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