Craniofacial Development Quiz
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Questions and Answers

What is the primitive stomatodeum?

  • A small bump on the developing face
  • A deep narrow depression in the developing face
  • A group of cells that will form the heart
  • A wide, shallow depression in the developing face (correct)
  • What separates the stomatodeum from the developing heart?

  • Branchial clefts
  • Pharyngeal pouches
  • Branchial arches (correct)
  • The buccopharyngeal membrane
  • How many branchial arches are there?

  • 4
  • There are 5 arches, but one of them disappears.
  • 6 (correct)
  • 5
  • What is the basic structure of each branchial arch?

    <p>Cartilage, nerve, and artery</p> Signup and view all the answers

    What is the significance of the first pharyngeal arch?

    <p>It forms the bones of the face</p> Signup and view all the answers

    What derives from the maxillary process of the first pharyngeal arch?

    <p>The structures that constitute the maxilla and the palate</p> Signup and view all the answers

    Which cartilage is derived from the first pharyngeal arch?

    <p>Meckel's cartilage</p> Signup and view all the answers

    Which muscle is derived from the second pharyngeal arch?

    <p>Stylohyoid</p> Signup and view all the answers

    What is the primary location of the mesoderm at the end of gastrulation?

    <p>Between the ectoderm and endoderm layers</p> Signup and view all the answers

    Which nerve is associated with the first pharyngeal arch?

    <p>CNV trigeminal</p> Signup and view all the answers

    Which of the following tissues is derived from the endoderm germ layer?

    <p>Gut</p> Signup and view all the answers

    What is the typical age range for surgically correcting a cleft palate?

    <p>3-8 months</p> Signup and view all the answers

    Which pharyngeal arch is associated with the constrictors of pharynx?

    <p>Fourth pharyngeal arch</p> Signup and view all the answers

    What is the correct sequence of germ layers from outermost to innermost at the end of gastrulation?

    <p>Ectoderm, Mesoderm, Endoderm</p> Signup and view all the answers

    What is a characteristic feature of Mandibulofacial dystostosis (Treacher-Collins syndrome)?

    <p>Underdeveloped facial bones and micrognathia</p> Signup and view all the answers

    Which of the following tissues is NOT derived from the mesoderm germ layer?

    <p>Epidermis</p> Signup and view all the answers

    Which cartilage is derived from the third pharyngeal arch?

    <p>Greater horns of hyoid</p> Signup and view all the answers

    What is often associated with cleft palate?

    <p>Mandibulofacial dystostosis (Treacher-Collins syndrome)</p> Signup and view all the answers

    Which pharyngeal arch is associated with the intrinsic muscles of the larynx?

    <p>Sixth pharyngeal arch</p> Signup and view all the answers

    What is a common feature of Acro-facial dysostosis?

    <p>A prominent forehead</p> Signup and view all the answers

    How many germ layers are present in the embryo at the end of gastrulation?

    <p>3</p> Signup and view all the answers

    What is Hemifacial microsomia characterized by?

    <p>Great variability in clinical manifestations</p> Signup and view all the answers

    What may be associated with Nager syndrome?

    <p>Both A and B</p> Signup and view all the answers

    Which of the following cranial nerves innervates the sensory receptors in the 1st arch of the tongue?

    <p>Cranial nerve V</p> Signup and view all the answers

    At which week of development does the distal tip of the tongue form?

    <p>6 weeks</p> Signup and view all the answers

    Which of the following muscles is derived from the head mesoderm and innervated by the vagus nerve X?

    <p>Palatoglossus muscle</p> Signup and view all the answers

    What is the term for the congenital anomaly where the tongue is tied to the floor of the mouth?

    <p>Ankylogossia</p> Signup and view all the answers

    Which of the following structures is formed from the median tongue bud?

    <p>Anterior 2/3 of the tongue</p> Signup and view all the answers

    Study Notes

    Pharyngeal Arches and Pouches

    • Form in the 4th and 5th weeks of development
    • 5 arches (1, 2, 3, 4, and 6) and 5 corresponding pouches
    • Each arch consists of a 'bar' of mesenchymal tissue, lined on the outside by ectoderm and inside by endoderm
    • Separated from each other by deep clefts on the outside and pouches on the inside

    Branchial Arches Structure

    • Cartilage, nerve, and artery components
    • Ectoderm outside, mesenchyme in the middle, and endoderm inside
    • Each arch has its own cranial nerve

    First Pharyngeal Arch

    • Gives origin to the bones of the two lower thirds of the face
    • Divided into maxillary and mandibular processes
    • Maxillary process forms the maxilla, premaxilla, zygomatic bone, and squamous part of the temporal bone
    • Innervated by cranial nerve V (trigeminal)

    Tongue Development

    • Multiple origins: foramen cecum, median tongue bud, and posterior tongue buds
    • Innervated by multiple nerves: cranial nerve V (trigeminal), facial nerve VII, glossopharyngeal IX, and vagus nerve X
    • Muscles from occipital somites (hypoglossal nerve XII) and head mesoderm (vagus nerve X)

    Pharyngeal Arch Cartilages

    • 1st arch: Meckel's cartilage (mandibular prominence)
    • 2nd arch: Reichert's or hyoid cartilage
    • 3rd arch: none
    • 4th arch: none
    • 6th arch: none

    Pharyngeal Arch Muscles

    • 1st arch: muscles of mastication
    • 2nd arch: muscles of facial expression
    • 3rd arch: stylopharyngeus
    • 4th arch: constrictors of pharynx
    • 6th arch: intrinsic muscles of the larynx

    Craniofacial Development

    • Derived from the three germ layers: ectoderm, mesoderm, and endoderm
    • Ectoderm forms epidermis and nervous system
    • Mesoderm forms skeleton, muscle, dermis, kidney, gonads, and blood
    • Endoderm forms gut, liver, lungs, thyroid, and pancreas

    Pharyngeal Arch Defects

    • Cleft palate
    • Mandibulofacial dystostosis (Treacher-Collins syndrome)
    • Acro-facial dysostosis
    • Nager Syndrome
    • Hemifacial microsomia (oto-mandibular syndrome)

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    Description

    This quiz covers the development of pharyngeal arches, pouches and clefts, and their association with the embryonic development of the craniofacial region. It also reviews embryological anomalies and syndromes.

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