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Questions and Answers

How did Alexander Fleming's observation of Penicillium contribute to the field of medicine?

  • It identified a new method for sterilizing laboratory equipment.
  • It explained the process of viral replication.
  • It identified the antibacterial properties of penicillin. (correct)
  • It demonstrated the potential of molds in food preservation.

Which statement accurately describes the relationship between the apoenzyme and its cofactor in an enzyme?

  • The apoenzyme and cofactor act independently and do not directly influence each other.
  • The cofactor is the protein part of all enzymes.
  • The apoenzyme is an inorganic ion that binds loosely to the cofactor.
  • The apoenzyme plus the cofactor form the holoenzyme. (correct)

Why are Gram-negative bacteria more resistant to certain antibiotics compared to Gram-positive bacteria?

  • Gram-negative bacteria have an outer membrane containing lipopolysaccharides, making them less permeable. (correct)
  • Gram-negative bacteria have a simpler cell wall structure, providing fewer targets for antibiotics.
  • Gram-negative bacteria lack the ability to produce enzymes that degrade antibiotics.
  • Gram-negative bacteria possess a thicker peptidoglycan layer, hindering antibiotic entry.

A study aims to determine the effectiveness of a new drug. What is the most likely consequence of using a very small sample size?

<p>Reduced statistical power and a higher chance of inconclusive results. (B)</p> Signup and view all the answers

Which of the following molecules of life is most directly involved in catalyzing biochemical reactions in cells?

<p>Proteins (B)</p> Signup and view all the answers

How might a significant change in temperature affect an enzyme's function, and why?

<p>It denatures (unfolds) the enzyme, disrupting its three-dimensional shape and active site. (B)</p> Signup and view all the answers

Imagine a bacterial species that thrives in extreme conditions, such as high salinity. What cell wall adaptation is MOST likely to be found in this extremophile compared to a typical bacterium?

<p>Unique cross-linking within the peptidoglycan to enhance stability. (C)</p> Signup and view all the answers

A researcher is investigating a metabolic pathway and observes that the pathway's final product is not being produced. Enzyme 2, which catalyzes a crucial step, is present but non-functional. Which of the following is the most likely explanation for Enzyme 2's inactivity?

<p>Enzyme 2 is lacking a necessary metal ion cofactor. (A)</p> Signup and view all the answers

Which of the following best describes the role of ATP in living organisms regarding energy?

<p>It is a usable form of energy converted from other forms through metabolism. (B)</p> Signup and view all the answers

How do enzymes increase the rate of biochemical reactions?

<p>By lowering the activation energy of the reaction. (B)</p> Signup and view all the answers

Which of these scenarios best represents the application of epidemiology?

<p>Analyzing data to determine the cause of a sudden increase in the incidence of food poisoning cases in a city. (B)</p> Signup and view all the answers

What is the primary distinction between eukaryotic and prokaryotic cells?

<p>Eukaryotic cells contain DNA organized into linear chromosomes within a nucleus. (C)</p> Signup and view all the answers

In an experiment studying the effect of a new fertilizer on plant growth, why is it important to have an experimental control group?

<p>To ensure the results are due to the fertilizer and not other factors. (C)</p> Signup and view all the answers

In a study examining the effectiveness of a new drug, what is the purpose of the experimental test group?

<p>To be exposed to the new drug being studied. (D)</p> Signup and view all the answers

Consider an experiment testing the effect of different pH levels on enzyme activity. Which setup represents the experimental control group?

<p>A group where the enzyme is kept at its optimal pH level. (C)</p> Signup and view all the answers

A scientist observes that a specific enzyme works best at $37^\circ C$. If the temperature is increased to $50^\circ C$, what is the most likely outcome?

<p>The enzyme will become denatured and lose its activity. (C)</p> Signup and view all the answers

If a scientist observes an unexpected result during an experiment, which of the following is the MOST appropriate next step according to the scientific method?

<p>Revise the hypothesis and design new experiments to test the revised hypothesis. (C)</p> Signup and view all the answers

Which of the following properties of water is MOST directly related to its ability to transport nutrients within living organisms?

<p>Polarity and solvent properties (A)</p> Signup and view all the answers

A scientist discovers a new unicellular organism. After analyzing its cellular structure, it is determined that the organism lacks a nucleus and any other membrane-bound organelles. Which classification BEST fits this organism?

<p>Prokaryote (C)</p> Signup and view all the answers

Which of the following characteristics is NOT typically associated with prokaryotic cells?

<p>Presence of a nucleus (A)</p> Signup and view all the answers

An organism is observed maintaining a stable internal body temperature despite fluctuations in the external environment. Which property of life does this BEST exemplify?

<p>Adaptation (B)</p> Signup and view all the answers

If a protein is denatured, meaning it loses its shape, which level of protein structure is MOST directly affected, potentially impacting its function?

<p>Quaternary structure (subunit arrangement) (A)</p> Signup and view all the answers

A scientist is studying a protein that catalyzes a specific biochemical reaction in cells. Which characteristic of proteins is MOST directly responsible for its ability to catalyze this reaction?

<p>The sequence of amino acids (D)</p> Signup and view all the answers

Why is maintaining a blood pH around 7.4 crucial for human physiology?

<p>It supports optimal protein structure and function. (D)</p> Signup and view all the answers

Which statement accurately describes the behavior of electrons in covalent bond formation?

<p>Electrons are shared between atoms to achieve a stable electron configuration. (A)</p> Signup and view all the answers

If two atoms have significantly different electronegativities and form a covalent bond, what property is the resultant molecule most likely to exhibit?

<p>Polarity, due to unequal sharing of electrons. (A)</p> Signup and view all the answers

How does the cytoplasm facilitate cellular processes?

<p>By providing a medium for organelle movement and cellular reactions. (B)</p> Signup and view all the answers

A cell is treated with a drug that disrupts the function of intermediate filaments. Which cellular function would be most directly affected?

<p>Maintenance of cell shape and organelle anchoring. (D)</p> Signup and view all the answers

Which of the following properties of electrons is most directly related to their role in cellular respiration?

<p>Their involvement in oxidation-reduction reactions. (B)</p> Signup and view all the answers

According to the endosymbiotic theory, which observation would provide the strongest evidence that mitochondria were once independent prokaryotic organisms?

<p>Mitochondria contain their own DNA and ribosomes. (A)</p> Signup and view all the answers

How does the cytoskeleton contribute to the overall function of a cell?

<p>It provides structural support, facilitates movement, and anchors organelles. (D)</p> Signup and view all the answers

Which characteristic is unique to organic compounds, differentiating them from inorganic compounds?

<p>The presence of carbon atoms. (C)</p> Signup and view all the answers

Which process is most directly dependent on the unique properties of electrons?

<p>Covalent bond formation (C)</p> Signup and view all the answers

In an experimental design, what is the primary purpose of the control group?

<p>To serve as a baseline for comparison against the experimental group. (B)</p> Signup and view all the answers

Which of the following statements accurately describes the role of peer review in academic publishing?

<p>It involves experts assessing the quality and validity of research before publication. (D)</p> Signup and view all the answers

What fundamental feature distinguishes eukaryotic cells from prokaryotic cells?

<p>The presence of a defined nucleus and membrane-bound organelles. (C)</p> Signup and view all the answers

Which set of nutrients are classified as macronutrients, essential for energy and growth?

<p>Carbohydrates, proteins, and fats. (D)</p> Signup and view all the answers

A researcher is investigating the effect of a new fertilizer on plant growth. What would be the most appropriate control group for this experiment?

<p>Plants grown without any fertilizer under the same conditions as the experimental group. (D)</p> Signup and view all the answers

A scientist submits a research paper to a journal. During the peer-review process, what is the most likely outcome?

<p>The paper is reviewed anonymously by experts, who provide feedback and suggestions for improvement. (A)</p> Signup and view all the answers

Considering the structural differences between prokaryotic and eukaryotic cells, which cellular process would differ most significantly?

<p>Cell division (A)</p> Signup and view all the answers

In a scientific study evaluating a new drug, why is random assignment of participants to control and treatment groups crucial?

<p>It helps to ensure that differences in outcomes are due to the treatment, not other factors. (B)</p> Signup and view all the answers

A researcher observes that a specific molecule is moving across a cell membrane with the help of a carrier protein, following its concentration gradient, without the input of energy. Which transport mechanism is most likely responsible for this movement?

<p>Facilitative diffusion (D)</p> Signup and view all the answers

Which of the following cellular processes is primarily carried out by the Golgi apparatus?

<p>Modifying, sorting, and packaging proteins and lipids (C)</p> Signup and view all the answers

After performing a Gram stain on a bacterial sample, you observe purple-colored cells under the microscope. What can you conclude about the bacteria?

<p>They have a thick peptidoglycan layer and are likely Gram-positive. (C)</p> Signup and view all the answers

Why are Gram-negative bacteria generally more resistant to antibiotics compared to Gram-positive bacteria?

<p>They have an outer membrane containing lipopolysaccharides. (C)</p> Signup and view all the answers

Which of the following is an example of homeostasis in the human body?

<p>All of the above (D)</p> Signup and view all the answers

A patient's blood tests reveal a consistently high blood pH (alkalosis). Which homeostatic mechanism is most likely failing in this scenario?

<p>Regulation of blood pH (A)</p> Signup and view all the answers

Which of the following best describes the relationship between the endoplasmic reticulum and the Golgi apparatus in protein processing and transport?

<p>The endoplasmic reticulum synthesizes proteins, and the Golgi apparatus further modifies, sorts, and packages them. (B)</p> Signup and view all the answers

Flashcards

Penicillium

Mold discovered by Alexander Fleming in 1928 with antibiotic properties.

Apoenzyme

The protein part of an enzyme.

Cofactor/Coenzyme

Non-protein component needed for enzyme activity; can be organic or inorganic.

Holoenzyme

Active enzyme formed when apoenzyme combines with its cofactor.

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Gram-positive Bacteria

Bacteria with a thick peptidoglycan layer that stains purple.

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Gram-negative Bacteria

Bacteria with a thin peptidoglycan layer and an outer membrane, stains pink.

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Sample Size in Research

The number of samples is a research study.

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Molecules of Life

Carbohydrates, lipids, proteins, and nucleic acids.

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Nucleic Acids

Carry genetic information; essential for protein synthesis.

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Organic Compounds

Contain carbon, from living things.

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Inorganic Compounds

Lack carbon, often minerals/salts.

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Hypothesis

Testable prediction in an experiment.

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Variables

Factors that can be changed in an experiment.

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Control Group

Baseline for comparison in an experiment.

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Peer Review

Experts evaluate research before publication.

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Prokaryotic Cells

Lack a nucleus; Bacteria/Archaea

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Covalent Bond

A type of chemical bond where atoms share electrons to form molecules; common between nonmetals.

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Cytoplasm

The jelly-like fluid in cells (excluding the nucleus) containing organelles and supporting cell structure.

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Cytoskeleton

Network of protein fibers (microtubules, microfilaments, intermediate filaments) providing cell shape and support.

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Electrons

Negatively charged particles orbiting the nucleus, crucial for chemical bonding and energy transfer.

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Endosymbiotic Theory

Theory that mitochondria and chloroplasts originated as prokaryotes engulfed by eukaryotic cells, forming a symbiotic relationship.

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Microtubules

Hollow tubes made of tubulin protein, maintaining cell shape and aiding cell division.

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Microfilaments

Fibers made of actin protein, involved in cell movement, contraction, and support.

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Intermediate Filaments

Provide mechanical support and anchor organelles within the cell; part of the cytoskeleton.

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Energy

The ability to do work or cause change, vital for all life processes.

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Enzymes

Proteins that speed up chemical reactions in organisms without being consumed.

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Epidemiology

Study of health-related patterns in populations, used to control health problems.

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Eukaryotic

Organisms with cells containing a nucleus and membrane-bound organelles.

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Experimental Control Group

Standard group in an experiment for comparison; does not receive the independent variable.

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Experimental Test Group

A group in an experiment that is exposed to the treatment being studied.

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Metabolism

Converts energy into a usable form, ATP.

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Enzymes

Lowers the activation energy of a reaction.

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Test Group Comparison

Compares results from a treatment group to assess the treatment's effects.

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Facilitative Diffusion

A passive transport process aided by carrier proteins to move molecules down their concentration gradient.

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Golgi Apparatus

Eukaryotic organelle; modifies, packages proteins/lipids into vesicles for secretion or internal use.

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Gram + Bacteria

Bacteria with a thick peptidoglycan layer. Appear purple after Gram staining.

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Gram - Bacteria

Bacteria with a thin peptidoglycan layer and an outer membrane, stain pink.

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Homeostasis

Self-regulating process maintaining internal stability despite external changes.

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Adequate Sample Size

Essential for reliable conclusions when analysing a test group.

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Random Assignment

Ensures treatment is the main factor influencing results in a study.

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Blood pH (Human)

Ideal blood pH for humans; essential for bodily functions.

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pH Indicators

Substances that change color depending on pH; litmus paper is an example.

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Water Polarity

Uneven electron distribution creates slightly charged poles.

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Process of Science

Observations → Hypothesis → Experiment → Analysis → Conclusion.

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Prokaryotic Organisms

Unicellular organisms lacking a nucleus or membrane-bound organelles.

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Properties of Life

Organization, energy use, growth, adaptation, and reproduction.

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Proteins

Essential molecules that catalyze reactions and replicate DNA.

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Water Cohesion

Attraction between water molecules due to hydrogen bonds.

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Study Notes

Acids vs Bases

  • Acids have a pH less than 7 and release hydrogen ions in water
  • Bases have a pH greater than 7 and accept hydrogens
  • Litmus paper turns red in acids and blue in bases
  • Acids taste sour, while bases taste bitter
  • Acids react with metals to produce hydrogen gas; concentrated bases can be corrosive
  • The pH scale measures acidity or alkalinity, with lower values being more acidic and higher values being more basic

Catabolic vs Anabolic Reactions

  • Catabolic reactions break down large molecules into smaller ones, releasing energy.
  • Anabolic reactions build larger molecules from smaller ones, consuming energy.
  • Catabolic reactions are exergonic, releasing energy
  • Anabolic reactions are endergonic, requiring energy
  • Catabolic reactions involve hydrolysis
  • Anabolic reactions involve dehydration synthesis
  • Digestion is an example of catabolic reactions
  • Protein synthesis is an example of anabolic reactions
  • Catabolic reactions are crucial for energy production
  • Anabolic reactions are essential for growth and repair

Cell Membrane Properties

  • The cell membrane is a semipermeable lipid bilayer
  • It regulates the passage of substances in and out of the cell
  • It is composed of phospholipids, proteins, and cholesterol
  • It maintains cell shape and protects organelles
  • It facilitates cell communication and signaling
  • It helps maintain homeostasis by regulating the internal environment

Components of the Cell Theory

  • All living organisms are composed of cells
  • Cells are the basic unit of life
  • All cells come from pre-existing cells
  • Schwann and Schleiden proposed the cell theory in the 19th century
  • Virchow later added the idea of cell division to the cell theory
  • Advanced technology, like microscopes, helped in developing the cell theory
  • The cell theory revolutionized how scientists viewed life and paved the way for modern cell biology

Control vs Experimental Groups

  • Control groups are exposed to the same conditions as experimental groups
  • The exception is the independent variable, which is not tested on control groups
  • The experimental group is subjected to independent variable being tested
  • Control groups provide a baseline for comparison with the experimental group
  • Random assignment helps reduce bias in group selection
  • Blinding techniques ensure objectivity in data collection

Discovery of Penicillin

  • Penicillin was discovered by Alexander Fleming in 1928
  • Penicillin is a powerful antibiotic produced by certain molds
  • Alexander Fleming noticed Penicillium's potential when he observed its ability to kill bacteria in a petri dish
  • Penicillin revolutionized treating bacterial infections and saved countless lives
  • Fleming's discovery paved the way for mass production of antibiotics and new medical treatments

Enzyme Components

  • Enzyme components include the apoenzyme, which is the protein part
  • Enzyme components include the cofactor or coenzyme, which can be organic molecules or inorganic ions
  • Prosthetic groups are tightly bound cofactors that are essential for enzyme function
  • Metal ions like zinc, magnesium, and iron can serve as cofactors for enzymes
  • Holoenzyme refers to the active enzyme formed when the apoenzyme combines with its cofactor or coenzyme
  • Enzymes can be denatured if their components are disrupted, leading to loss of function

Gram-Positive and Gram-Negative Differences

  • Gram-positive bacteria have a thick peptidoglycan layer retaining the crystal violet stain
  • Gram-positive bacteria appear purple under microscopy
  • Gram-negative bacteria has a thinner layer and appear pink
  • Gram-positive are generally more susceptible to antibiotics targeting the cell wall due to their thicker peptidoglycan layer
  • Gram-negative have an outer membrane containing lipopolysaccharides that can trigger a stronger immune response
  • Gram-positive produce a simpler cell wall structure without an outer membrane
  • Gram-negative are more resistant to certain antibiotics and disinfectants due to their complex outer membrane

Importance of Sample Size

  • Sample size is crucial for reliable results
  • Sample size affects statistical power, precision, and generalizability in research
  • A larger sample size increases the likelihood of detecting true effects
  • Small sample sizes may lead to misleading or inconclusive results
  • Sample size determination should consider variability and effect size
  • Statistical analyses are more robust with larger sample sizes

Molecules of Life

  • Molecules of life are essential organic compounds found in living organisms
  • These include carbohydrates, lipids, proteins, and nucleic acids
  • Carbohydrates provide energy and structural support
  • Lipids are important for storing energy and forming cell membranes
  • Proteins play crucial roles in enzymes, structure, and signaling
  • Nucleic acids carry genetic information and are essential for protein synthesis

Organic vs Inorganic

  • Organic compounds contain carbon and are typically derived from living organisms
  • In contrast, inorganic compounds lack carbon and are often minerals or salts
  • Organic molecules usually exhibit covalent bonding
  • Inorganic molecules can have various types of bonds
  • Organic compounds include carbohydrates, lipids, proteins, and nucleic acids
  • Inorganic compounds include water, salts, and metals
  • Organic compounds are more complex and have a wider range of functions in living organisms compared to inorganic compounds
  • Study of organic vs. inorganic compounds is crucial in understanding the chemistry of life and the environment

Parts of an Experiment

  • Key parts of an experiment include the hypothesis, variables, control group, experimental group, data collection methods, and conclusions
  • The hypothesis is a testable prediction
  • Variables are factors that can be changed
  • The control group serves as a baseline for comparison
  • The experimental group receives the treatment

Peer Review Process

  • Peer review process involves experts in the field evaluating the quality and validity of research articles before publication.
  • Peer review helps maintain research quality and integrity in academic publications
  • Peer review ensures that research articles meet specific standards for publication
  • Peer review provides feedback to authors for improving their research
  • Peer review usually involves anonymous reviewers to maintain objectivity

Prokaryotic vs Eukaryotic Cells

  • Prokaryotic cells lack a true nucleus and membrane-bound organelles
  • Eukaryotic cells have a defined nucleus and organelles enclosed within membranes
  • Prokaryotic cells are typically smaller and simpler in structure compared to eukaryotic cells
  • Eukaryotic cells are found in plants, animals, fungi, and protists
  • Prokaryotic cells are found in bacteria and archaea
  • Eukaryotic cells undergo mitosis for cell division
  • Prokaryotic cells reproduce asexually through binary fission
  • Eukaryotic cells exhibit more complex metabolic processes and can be multicellular
  • Prokaryotic cells are mostly unicellular

Sources of Macronutrients

  • Macronutrients are essential nutrients that the body requires in large amounts for energy and growth
  • They include carbohydrates, proteins, and fats
  • Carbohydrates are found in foods like bread, pasta, and fruits
  • Proteins can be sourced from meat, dairy products, and legumes
  • Fats are commonly found in oils, nuts, and avocados
  • Balancing macronutrient intake is crucial for maintaining a healthy diet

Synthesized Amino Acids

  • Synthesized amino acids are artificially created versions of naturally occurring amino acids, typically produced through chemical processes.
  • Key methods for synthesizing amino acids include solid-phase peptide synthesis and liquid-phase peptide synthesis
  • Synthesized amino acids are used in research, drug development, and food production.
  • These artificial amino acids can have modified structures that provide unique properties or functions
  • Synthesized amino acids must be carefully designed to mimic the properties of their natural counterparts

The Steps of Science

  • The Steps of Science provide a systematic approach to conducting research
  • This includes making observations, forming hypotheses, conducting experiments, analyzing data, and drawing conclusions
  • Observations are key facts gathered through the senses
  • Hypotheses are testable explanations for observations
  • Experiments test the validity of hypotheses
  • Data analysis involves organizing and interpreting results

Water- or Fat-Soluble Vitamins

  • Vitamins are classified as water-soluble or fat-soluble based on their solubility in water or fat
  • Water-soluble vitamins dissolve in water and are not stored in the body
  • Water-soluble vitamins include B-complex vitamins and vitamin C
  • Fat-soluble vitamins include vitamins A, D, E, and K.
  • Excess water-soluble vitamins are usually excreted in the urine, while excess fat-soluble vitamins can be stored in the body.
  • A balanced diet with a variety of foods is important to ensure adequate intake of both water- and fat-soluble vitamins.

Key Terms

  • Acid: A chemical substance with a pH below 7 that releases hydrogen ions in water

  • Acids can be classified as strong or weak based on their ability to dissociate into ions in water

  • Some common examples of acids include lemon juice, vinegar, and battery acid

  • Acids can react with metals to produce hydrogen gas

  • Acids can also be found in the stomach, where they aid in the digestion process

  • Activation energy: The minimum amount of energy needed for a chemical reaction to occur

  • Activation energy is required because it helps overcome the energy barrier between the reactants and the transition state

  • Increasing the temperature increases the kinetic energy of the molecules, allowing them to overcome the activation energy more easily

  • Catalysts lower the activation energy by providing an alternative reaction pathway with a lower energy barrier

  • The activation energy can be influenced by factors such as concentration, surface area, and the presence of a catalyst

  • Active Transport: A biological process that moves molecules across cell membranes against a concentration gradient, requiring energy, usually in the form of ATP

  • Active transport involves carrier proteins that facilitate movement of ions or molecules

  • Two types of active transport are primary (direct use of ATP) and secondary (uses electrochemical gradient)

  • Examples include sodium-potassium pump, proton pump, and cotransport

  • It is key for maintaining cell potential and homeostasis in cells

  • Adhesion: The property of different substances to adhere or stick together, usually due to intermolecular forces

  • Adhesion plays important roles in various biological processes, such as cell adhesion and the transport of water and nutrients in plants

  • Capillary action is an example of adhesion, where water molecules adhere to the walls of a narrow tube and are pulled upward against gravity

  • Adhesion is crucial for wound healing, as it helps cells stick together and form new tissues

  • Geckos are known for their ability to climb walls and ceilings due to their specialized toe pads that exhibit strong adhesion to surfaces

  • Anabolic: Anabolic processes in living organisms involve building complex molecules from simpler ones, requiring energy input for growth, repair, and maintenance of cells and tissues

  • Protein synthesis is a key anabolic process responsible for creating proteins essential for cellular structure and function

  • Anabolic reactions are endergonic, meaning they require energy input to proceed

  • These processes are crucial for growth and development, as well as the repair of tissues and maintenance of body structures

  • Anabolic activities are often associated with activities such as muscle building and tissue repair in organisms

  • Anecdotal Evidence: Personal observations or experiences that are not based on systematic data collection or scientific research

  • It is subjective and can be influenced by bias or individual perspectives

  • Although anecdotal evidence can be compelling, it is generally considered weaker compared to empirical evidence

  • It is often used to generate hypotheses or as a starting point for further scientific investigation

  • Researchers must be cautious when relying on anecdotal evidence due to its limited reliability and potential for inaccuracies

  • Atom: The basic unit of matter, consisting of a nucleus composed of protons and neutrons, surrounded by electrons in energy levels

  • Atoms are electrically neutral because they have equal numbers of protons and electrons

  • The nucleus is very dense, containing most of the atom's mass, while the electrons occupy much larger regions of space

  • Elements are defined by the number of protons present in their atoms

  • Electrons occupy distinct energy levels or orbitals around the nucleus, with each level capable of holding a specific number of electrons

  • Atomic Mass: Refers to the average mass of the atoms in a sample of an element, taking into account the abundance of each isotope

  • The atomic mass unit (amu) is used to express atomic mass

  • Atomic mass is found on the periodic table as the decimal number below the element's symbol

  • Isotopes of an element have the same atomic number but different atomic masses

  • The atomic mass of an element is crucial for calculating molar mass and stoichiometric calculations

  • Atomic Number: Refers to the total number of protons in an atom's nucleus

  • Atomic number determines the element and its chemical properties

  • All atoms of the same element have the same atomic number

  • Atomic number is uniquely associated with each element on the periodic table

  • The atomic number can be found above or below the element's symbol in the periodic table

  • Base: A substance that can accept or react with hydrogen ions (protons)

  • Bases have a pH value greater than 7 on the pH scale

  • Examples of bases include sodium hydroxide (NaOH) and ammonia (NH3)

  • Bases are often used in the laboratory to neutralize acids

  • The chemical formula of a base usually contains hydroxide ions (OH-)

  • Biology: Scientific exploration involving the study of life and organisms, inclusive of their physical: structure, chemical processes, molecular interactions, developments and evolutionary relationships.

  • Lays the foundation for understanding the complex nature of life

  • Emphasizes on cellular structure and functions, genetics and evolution

  • Incorporates the study of ecosystems, behavior, and biodiversity

  • Includes subfields such as microbiology, botany and zoology

  • Bulk Transport: Refers to the movement of large amounts of materials across the cell membrane

  • Materials are often transported in bulk to ensure efficient distribution throughout the organism

  • Examples of bulk transport include phagocytosis and pinocytosis

  • Bulk transport is an active process that requires energy in the form of ATP

  • In plants, bulk transport of water and nutrients occurs through structures like xylem vessels

  • Carbohydrates: Organic Molecules made up of carbon, hydrogen, and oxygen atoms

  • Carbohydrates serve as a primary energy source

  • Carbohydrates are found in foods like bread, rice, and fruits

  • Carbohydrates are classified as monosaccharides, disaccharides, or polysaccharides based on the number of sugar units they contain

  • Glucose, fructose, and galactose are examples of monosaccharides

  • Lactose, sucrose, and maltose are examples of disaccharides

  • Starch, glycogen, and cellulose are examples of polysaccharides

  • Catabolic: Processes involve the breakdown of complex molecules into simpler substances, releasing energy in the process

  • Catabolism includes processes like digestion, cellular respiration, and fermentation

  • Enzymes play a crucial role in catalyzing catabolic reactions

  • ATP is often produced during catabolic reactions, providing energy for cellular activities

  • Catabolic pathways help organisms obtain energy by breaking down nutrients

  • Cell Membrane: Semi-permeable barrier encircling cells, regulating molecular traffic to maintain a stable internal environment and supporting cellular structure

  • It is composed of a lipid bilayer interspersed with proteins

  • It is involved in processes like endocytosis, exocytosis, and signal transduction

  • Proteins embedded in the membrane fulfill functions like transport and receptor signaling

  • Membrane fluidity is influenced by lipid composition and temperature

  • Cell Theory: A fundamental concept in biology that states all living organisms are composed of cells: Basic unit of structure and function in living organisms, and all: Cells arise from pre-existing cells

  • Cells are the smallest unit of life and are capable of carrying out essential functions

  • The discovery of cells and the development of cell theory is credited to scientists Robert Hooke, Anton van Leeuwenhoek, and Matthias Schleiden and Theodor Schwann

  • The cell theory was proposed in the mid-19th century and revolutionized the understanding of life and biology as a whole

  • The cell theory serves as the foundation for many branches of biology, including genetics, microbiology, and cell biology

  • Cell Wall: A rigid outer layer found in plants, fungi, and some prokaryotes, providing support and protection for the cell

  • The cell wall is made up of cellulose in plants, chitin in fungi, and peptidoglycan in prokaryotes

  • The cell wall is not present in animal cells

  • Cell walls allow plants to stand upright and resist mechanical stress

  • The cell wall also helps in preventing the entry of pathogens and provides shape to the cell

  • Chloroplast: Double membrane-bound organelles found in plants and algae that contain chlorophyll, responsible for photosynthesis

  • Chloroplasts are the site of photosynthesis, where sunlight energy is converted into chemical energy

  • The two main stages of photosynthesis, light-dependent and light-independent reactions, occur in separate regions of the chloroplast

  • Chloroplasts contain their own DNA and ribosomes, allowing them to synthesize their own proteins

  • Chlorophyll, which gives plants their green color, is located in the thylakoid membranes within the chloroplast

  • Coenzymes: Are organic molecules that are required for the proper functioning of enzymes, participating in enzyme-catalyzed reactions to transfer chemical groups between molecules.

  • Coenzymes act as cofactors, which means they bind to the enzyme and help it carry out its function

  • They can be derived from vitamins or other organic molecules and are often modified during the Reaction

  • Coenzymes are often involved in energy transfer processes, such as ATP synthesis

  • Some coenzymes function as carriers of electrons or other chemical groups in metabolic pathways

  • Cofactors: Are Molecules required for the proper functioning of enzymes, helping them catalyze certain reactions effectively

  • Cofactors can be either inorganic ions (like zinc or magnesium) or organic molecules (like vitamins)

  • Some cofactors are permanently bound to the enzyme, while others can bind and detach as needed

  • Cofactors assist enzymes by providing additional chemical groups or helping with electron transfer reactions

  • Enzymes are often inactive without their cofactors and may require cofactor binding to become fully functional

  • Cohesion: The property of water molecules to stick together due to hydrogen bonding, forming a continuous chain that allows water to flow and be pulled upward in plants

  • The cohesion between water molecules creates surface tension, allowing small insects to walk on water

  • Cohesion is responsible for the transport of water and nutrients within plants through the xylem

  • Cohesion helps to maintain the shape and structure of water droplets

  • Cohesion is important for the movement of water from the roots to the leaves in plants through capillary action

  • Covalent Bond: A type of chemical bond where two atoms share electrons, resulting in the formation of a molecular structure

  • Covalent bonds are formed between nonmetallic elements

  • The electrons are shared in such a way that the atoms involved achieve a stable electron configuration

  • Covalent bonds can be polar or nonpolar, depending on the electronegativity difference between the atoms

  • These bonds are stronger than ionic bonds and weaker than metallic bonds

  • Cytoplasm: The jelly-like fluid that fills the cell, excluding the nucleus. It contains various organelles and supports cell structure while housing cellular processes.

  • Cytoplasm is composed of water, salts, proteins, and other molecules

  • Cytoplasm allows for the movement of organelles within the cell

  • Many cellular reactions, including protein synthesis, occur in the cytoplasm

  • Cytoplasm helps maintain cellular shape and cushions the organelles

  • Cytoskeleton: Network of Protein Fibers that provides shape, structure, and support to cells

  • The cytoskeleton is composed of three main types of fibers: microtubules, microfilaments, and intermediate filaments

  • Microtubules are hollow tubes made of the protein tubulin, and they help maintain cell shape and assist in cell division

  • Microfilaments are made of the protein actin and are involved in cell movement, contraction, and support

  • Intermediate filaments provide mechanical support and help anchor organelles within the cell

  • Electrons: Negatively charged particles that orbit the nucleus of an atom

  • Electrons play a crucial role in chemical bonding and the formation of molecules

  • Electrons exist in different energy levels or shells around the nucleus

  • Electrons are involved in the process of oxidation-reduction reactions in living organisms

  • Electrons are involved in the transfer of energy through electron transport chains in cellular respiration

  • Endosymbiotic Theory: Holds that mitochondria and chloroplasts in eukaryotic cells used to be individual prokaryotic organisms that later formed a symbiotic relationship with eukaryotes.

  • It was proposed by biologist Lynn Margulis

  • The theory explains the origin of eukaryotes from prokaryotes

  • Supports evolution by suggesting that collaboration can drive complexity

  • Supported by genetic and functional similarities between mitochondria, chloroplasts, and bacteria

  • Energy: Ability to do work or cause changes, playing a vital role in all life processes from movement to growth

  • "Energy" is mostly derived from food in living organisms

  • Metabolism involves converging "Energy" into a usable form; ATP

  • "Energy" in ecosystems flows from producers to consumers

  • "Energy" conservation is a fundamental concept in life processes, aligning with the 1st law of thermodynamics

  • Enzymes: are proteins that act as catalysts in living organisms, expediting chemical reactions without being consumed by those processes.

  • Enzymes work by lowering the activation energy of a reaction

  • Each enzyme catalyses a specific reaction, often associated with its name

  • Enzymes can be influenced by factors such as temperature and pH

  • Enzyme activity can be inhibited, either completely (non-competitive) or temporarily (Competitive)

  • Epidemiology: Study of the distribution and determinants of health-related states or events in specific populations, and the application of This study to control health problems

  • Involves analyzing patterns, causes, and effects of health and disease in populations

  • Epidemiologists use various methods to identify risk factors and improve public health outcomes

  • Key aspects include disease surveillance, outbreak investigation, and statistical analysis of data

  • Epidemiology plays a crucial role in shaping public health policies and interventions

  • Eukaryotic: Organisms are characterized by the presence of a nucleus and other membrane-bound organelles

  • Eukaryotic cells include plants, animals, fungi, and protists

  • The DNA in eukaryotic cells is organized into linear chromosomes within the nucleus

  • Eukaryotic cells are generally larger in size than prokaryotic cells

  • Eukaryotic organisms are able to carry out complex functions due to the specialized organelles within their cells.

  • Experimental Control Group: Is a Standard Group used as a baseline for comparison in an experiment to determine the effect of the independent variable.

  • Ensures any changes observed are due to the independent variable

  • Helps in establishing cause-and-effect relationships

  • Receives all factors present in the experimental group except for the independent variable

  • Provides a basis for comparison to assess the impact of the independent variable

  • Experimental Test Group: A group in an experiment that is exposed to the experimental treatment or condition being studied

  • Typically compared to a control group that does not receive the treatment

  • Results from the test group are compared to evaluate the effects of the treatment

  • Important to have a large enough sample size in the test group for reliable conclusions.

  • Random assignment helps ensure that factors other than the treatment do not influence the results.

  • Facilitative Diffusion: The passive movement of molecules across a cell membrane with the help of specific carrier proteins

  • Carrier proteins aid in transporting molecules down their concentration gradient

  • It allows for the movement of larger or charged molecules that cannot diffuse through the lipid bilayer

  • Facilitative diffusion does not require energy input from the cell

  • It is crucial for the uptake of important nutrients and ions by cells

  • Golgi apparatus: an organelle found in eukaryotic cells that processes and packages proteins and lipids

  • The Golgi apparatus consists of flattened membranous sacs called cisternae

  • It receives proteins from the endoplasmic reticulum and modifies them through processes such as glycosylation

  • It then packages and sorts the modified proteins into vesicles

  • Gram + Bacteria: A Gram + bacteria have a thick layer of peptidoglycan in their cell walls that retains the crystal violet stain in the presence of Gram staining.

  • These bacteria appear purple under a microscope after the staining process

  • They are usually sensitive to antibiotics like penicillin that target the cell wall

  • These bacteria have common examples such as staphylococcus and streptococcus species.

  • Gram - Bacteria: A Gram - bacteria have cell walls with a thin peptidoglycan layer and an outer membrane that contains lipopolysaccharides, with the presence of Gram staining

  • The bacteria are commonly more resistant to antibiotics due to their outer membrane

  • The bacteria contain common examples such as E. coli, Pseudomonas aeruginosa, and Salmonella

  • Gram-negative bacteria are associated with various infections in humans such as pneumonia, urinary tract infections, and meningitis

  • Gram-negative bacteria are classified based on their shape, metabolism, and other characteristics

  • Homeostasis: The self-regulating process by which biological systems maintain stability while adjusting to changing external conditions.

  • Involved in maintaining bodily temperature, fluid balance, and blood pH levels.

  • Regulated largely by the Endocrine and nervous systems.

  • Hypertonic: In biological terms, “ Hypertonic,”refers to a solution with A higher Solute concentration related compared to another solution.

  • It can cause cells to shrink in the process called crenation.

  • Aquatic organisms may face challenges due to hypertonic solutions

  • A hypotonic environment refers to a solution with a lower solute concentration, allowing the net movement of water molecules into the cell via osmosis

  • In a hypotonic solution, a cell will swell as water moves inside.

  • This is due to higher solute concentration inside the cell

  • Inorganic Molecule: A molecule composed of compounds that do not contain carbon-hydrogen bonds, the examples include water, salts, and metals.

  • Inorganic molecules play essential roles in biological systems, such as in maintaining PH balance transporting ions

  • Inorganic salts provide necessary nutrients for cellular functions and are also involved in nerve signal transmission.

  • Ionic Bond: A type of chemical bond formed through the electrostatic attraction between oppositely charged ions, typically between: A metal and anon-metal.

  • Ionic bonds create compound structures termed as ‘ ionic compounds.’

  • These bonds influence cell signaling and interactions.

  • They determine properties of cell balance.

  • Isotonic : Refers to a state where a cell and surrounding solution have equal solute concentrations, which results in no net movement of water.

  • Isotonic solutions are ideal in human cells to maintain normal functionality.

  • Isotonic avoids cell damage.

  • Isotonic solutions are commonly used in intravenous in medical conditions.

  • Lipids are a diverse group of organic compounds, that aren't soluble in water but soluble in nonpolar organic solvents, and primarily composed of carbon, hydrogen and oxygen.

  • Lipids serve as a function for storing energy and thermal insulation.

  • they're vital for Energy storage.

  • Dietary lipids can essential fatty acids that cannot be synthesized within the body.

  • Lysosomes: Small membrane-bound organelles containing digestive enzymes that break down waste materials and cellular debris

  • Lysosomes are involved in the process of autophagy, where the cell degrades and recycles it's own components.

  • Macronutrients: Essential nutrients with large quantities, are required by living organisms for growth, development and energy production

  • There are three main macronutrients: carbohydrates, proteins and fats.

  • Carbohydrates are the body’s preferred source of energy for daily needs.

  • Malnutrition , is a Condition shown by an insufficient diet that can lead to health problems.

  • Malnutrition can result in stunted growth which results in a weakened immune system with an increased susceptibility immune suppression

  • Metabolism: Chemicals occurrences in a living organisms to maintain life.

  • It is categorized into catabolism(breaking down) and anabolism (building up)

  • some Factors affecting metabolism are age and genes.

  • Micronutrients: Essential nutrients required by the body in small amounts for optimal health and proper fuctioning of various Biological processes.

  • These nutrient play a significant role in contributing to the daily development and growth.

  • Minerals: essential Nutrients that the human body needs in small amounts and plays a crucial role in maintaining proper functioning.

  • play a key role in nerve, muscle, and maintaining fluid balance.

  • Mitochondria: Organelles which are found in eukaryotic cells which function and as the cell's energy providers by generation the most of the ATP energy cells require

  • The amount of mitochondrion can depend on the cell need.

  • Molecule: the smallest unit of a chemical compound that retains the chemical characteristics of that compound.

  • Constructed of two or more Atoms bonded together.

  • may be simple or complex.

  • Neutrons: subatomic particles commonly found in the nucleus in an Atom which provides stability in stabilizing the Atom.

  • neutrons have a mass similar to protons.

  • Nucleic: Acids

  • Nucleus of a Cell: DNA in form of chromosomes

  • Nucleus of Atom: located in the central core of an atom.

  • Organic Molecule: Chemical compound that consist of carbon Atoms in long rings and compounds.

  • Osmosis: Movement of water Molecules to help with a high amount of Solute Concentrations.

  • Passive Transport: Transports items in the cell

  • Peer Reviewed Journals: Reviewed by Expert

  • Peer Review: A process of reviewing experts

  • Penicllium: Spores found in diverse environments.

  • Phospholipid: a class of lipids that consist of all membranes

  • PH scale: determine acidity within the solution

  • Polarity of Water: Molecules to help cohesion.

  • Process of Science: To draw conclusions to advance understanding of Knowledge.

  • Prokaryotic: a single organism which lacks organelles

  • Properties of Life: to help with energy and reproduction

  • Proteins: Composed of complex amino acids.

  • Protons: Positively charged particles with energy.

  • Randomized Clinical Trail: assign randomly

  • Ribosome: The process is known as translation

  • Rough Endoplasmic Reticulum: involved in synthesis and movement.

  • Sample Size: Data points collected for Statistical Reliability

  • Science: Understanding the Natural Life

  • Scientific Method: systematic procedure for conducting research

  • Scientific theory: underpinned explanation of natural phenomena

  • Simple Diffusion: The Movement of molecules in an orderly way.

  • Smooth Endoplasmic Reticulum: Network of tabular membranes

  • Solute: A substance that is dissolved in a solution

  • Solute, changes physical properties

  • Solution: A solute that is dissolved in a Solvent

  • Solvent : aids in molecular transportation

  • Vitamins organic compounds for body

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