9 Questions
What is the role of corticotropin-releasing hormone (CRH) in initiating labor?
Induces surfactant production in the placenta
Which enzyme is the main enzyme involved in inflammation when prostaglandins are derived from arachidonic acid?
Cyclo-oxygenase (COX)
What is the key role of surfactant protein A in murine parturition?
Prepares lungs for gaseous exchange
What pathway is used to initiate labor when synthetic prostaglandins are administered on the vagina and cervical muscles?
Inflammatory pathway
What is the main role of NF-KB cytokine in relation to inflammatory mediators?
Downregulated by progesterone
What is a common factor affecting the success of labor power?
Contractions
In what stage of labor does cervical opening, changing size, and dilating primarily occur?
First stage
What hormone is responsible for causing contractions during labor?
Oxytocin
What happens when oxytocin binds to oxytocin receptors (OTR) on myometrial cells?
'Oxytocin' stimulates uterine contractions
Learn about the role of Corticotropin-Releasing Hormone (CRH) released by the placenta in initiating labor and its feed-forward pathways in both mother and fetus. Understand how levels of CRH increase in response to maternal and fetal stress hormones, and the production of surfactant protein A by CRH to prepare the lungs for gaseous exchange.
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