Corticotropin-Releasing Hormone (CRH) and its Role in Initiation of Labor
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Questions and Answers

What is the role of corticotropin-releasing hormone (CRH) in initiating labor?

  • Induces surfactant production in the placenta (correct)
  • Increases levels in response to maternal and fetal stress hormones
  • Inhibits uterine contractions
  • Stimulates inflammatory pathways

    • Which enzyme is the main enzyme involved in inflammation when prostaglandins are derived from arachidonic acid?

  • Lipase
  • Amylase
  • Cyclo-oxygenase (COX) (correct)
  • Protease

    • What is the key role of surfactant protein A in murine parturition?

  • Prepares lungs for gaseous exchange (correct)
  • Inhibits labor contractions
  • Promotes uterine contractions
  • Induces inflammatory pathways

    • What pathway is used to initiate labor when synthetic prostaglandins are administered on the vagina and cervical muscles?

    <p>Inflammatory pathway</p> Signup and view all the answers

    What is the main role of NF-KB cytokine in relation to inflammatory mediators?

    <p>Downregulated by progesterone</p> Signup and view all the answers

    What is a common factor affecting the success of labor power?

    <p>Contractions</p> Signup and view all the answers

    In what stage of labor does cervical opening, changing size, and dilating primarily occur?

    <p>First stage</p> Signup and view all the answers

    What hormone is responsible for causing contractions during labor?

    <p>Oxytocin</p> Signup and view all the answers

    What happens when oxytocin binds to oxytocin receptors (OTR) on myometrial cells?

    <p>'Oxytocin' stimulates uterine contractions</p> Signup and view all the answers

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