Corticotropin-Releasing Hormone (CRH) and its Role in Initiation of Labor
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Questions and Answers

What is the role of corticotropin-releasing hormone (CRH) in initiating labor?

  • Induces surfactant production in the placenta (correct)
  • Increases levels in response to maternal and fetal stress hormones
  • Inhibits uterine contractions
  • Stimulates inflammatory pathways

Which enzyme is the main enzyme involved in inflammation when prostaglandins are derived from arachidonic acid?

  • Lipase
  • Amylase
  • Cyclo-oxygenase (COX) (correct)
  • Protease

What is the key role of surfactant protein A in murine parturition?

  • Prepares lungs for gaseous exchange (correct)
  • Inhibits labor contractions
  • Promotes uterine contractions
  • Induces inflammatory pathways

What pathway is used to initiate labor when synthetic prostaglandins are administered on the vagina and cervical muscles?

<p>Inflammatory pathway (D)</p> Signup and view all the answers

What is the main role of NF-KB cytokine in relation to inflammatory mediators?

<p>Downregulated by progesterone (C)</p> Signup and view all the answers

What is a common factor affecting the success of labor power?

<p>Contractions (A)</p> Signup and view all the answers

In what stage of labor does cervical opening, changing size, and dilating primarily occur?

<p>First stage (C)</p> Signup and view all the answers

What hormone is responsible for causing contractions during labor?

<p>Oxytocin (D)</p> Signup and view all the answers

What happens when oxytocin binds to oxytocin receptors (OTR) on myometrial cells?

<p>'Oxytocin' stimulates uterine contractions (D)</p> Signup and view all the answers

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