Podcast
Questions and Answers
Which of the following corticosteroids is administered parenterally?
Which of the following corticosteroids is administered parenterally?
- Methylprednisolone (correct)
- Ciclesonide
- Fluticasone propionate
- Budesonide
What class of drugs includes Salmeterol and Formoterol?
What class of drugs includes Salmeterol and Formoterol?
- Mast cell stabilizers
- Leukotriene modulators
- Long-acting β₂-agonists (correct)
- Short-acting β₂-agonists
Which of the following drugs should be preferred for immediate relief during an asthma attack?
Which of the following drugs should be preferred for immediate relief during an asthma attack?
- Salmeterol
- Montelukast
- Albuterol (correct)
- Ipratropium
What is the duration of action for short-acting β₂-agonists (SABAs)?
What is the duration of action for short-acting β₂-agonists (SABAs)?
Which type of drug can be safely used during pregnancy among bronchodilators?
Which type of drug can be safely used during pregnancy among bronchodilators?
Which medication is classified as a Monoclonal Anti-IgE Antibody?
Which medication is classified as a Monoclonal Anti-IgE Antibody?
What is the primary action of bronchodilators in the treatment of asthma?
What is the primary action of bronchodilators in the treatment of asthma?
Which of the following is a 5-Lipoxygenase Inhibitor used in asthma therapy?
Which of the following is a 5-Lipoxygenase Inhibitor used in asthma therapy?
Flashcards
Selective β₂-Agonists
Selective β₂-Agonists
Mainstay bronchodilators activating β₂-adrenoceptors for airway relaxation.
Bronchodilators for Asthma
Bronchodilators for Asthma
Drugs that relax bronchial smooth muscles, providing rapid symptom relief for asthma.
SABAs
SABAs
Short-acting β₂-agonists, providing rapid, short-term relief (2-4 hours).
LABAs
LABAs
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Albuterol
Albuterol
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Corticosteroids for Asthma
Corticosteroids for Asthma
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Inhaled Corticosteroids
Inhaled Corticosteroids
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Mast Cell Stabilizers
Mast Cell Stabilizers
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Study Notes
Corticosteroids
- Oral corticosteroids include Prednisone, Prednisolone, Methylprednisolone, and Dexamethasone
- Parenteral corticosteroids include Hydrocortisone and Methylprednisolone
- Inhalational corticosteroids include Beclomethasone dipropionate, Fluticasone propionate/furoate, Budesonide, Flunisolide, Ciclesonide, and Triamcinolone, Mometasone
Long Acting β₂-Agonists (LABAs)
- LABAs include Salmeterol, Formoterol, Eformoterol, Bambuterol, Indacaterol, and Olodaterol
- Both SABA and LABA groups of drugs activate β₂-adrenoceptors
- LABAs have a longer duration of action, 6-12 hours, than SABAs
Mast Cell Stabilizers
- Sodium cromoglycate (cromolyn sodium) and Nedocromil
Leukotriene Modulators
- 5-Lipoxygenase inhibitors: Zileuton
- Cysteinyl Leukotriene Receptor Antagonists (LTRAs): Zafirlukast, Montelukast, Iralukast, Pranlukast
Monoclonal Anti-IgE Antibody
- Omalizumab
Miscellaneous Anti-asthma Drugs
- Benralizumab, Tezepelumab, Mepolizumab, Dupilumab, Reslizumab, Nitric oxide donors
Bronchodilators
- Bronchodilators relieve asthmatic symptoms and improve pulmonary function by relaxing bronchial smooth muscle
- Bronchodilators are often termed relievers or rescue drugs because they provide rapid symptomatic relief but do not control the disease process
- Nonselective sympathomimetics, selective β₂-agonists, methylxanthines, and anti-muscarinic drugs like ipratropium, tiotropium, and others are bronchodilators.
Short Acting β₂-Agonists (SABAs)
- SABAs include Salbutamol (albuterol), Terbutaline, Remiterol, Fenoterol, Pirbuterol, and Bitoterol
- SABAs have a shorter duration of action (2-4 hours) compared to LABAs (6-12 hours).
- SABAs are the drugs of choice to manage acute asthma attacks(bronchospasm).
- SABAs are preferred over the other drugs because they are less likely to activate the other adrenoceptors.
- Salbutamol and terbutaline are commonly used SABAs.
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Description
Test your knowledge on various types of asthma medications, including corticosteroids, long-acting β₂-agonists, mast cell stabilizers, and leukotriene modulators. This quiz covers their classifications, examples, and mechanisms of action. Perfect for students and professionals in the medical field!
