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Control Of Microorganisms: Antibiotics Quiz

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Questions and Answers

Which type of antibiotics are used to limit the growth and reproduction of bacteria?

Broad-spectrum antibiotics
Bacteriostatic antibiotics (correct)
Antifungal antibiotics
Bactericidal antibiotics

What is the function of sulphonamides in bacterial cells?

They act as competitive antagonists of PABA in folic acid synthesis (correct)
They inhibit protein synthesis in bacteria
They target the cell wall of bacteria
They disrupt the DNA replication process in bacteria

In Kirby–Bauer antibiotic testing, what does it mean when a bacterial strain is classified as 'resistant'?

The bacteria show some sensitivity to the antibiotic
The bacteria are not affected by the antibiotic (correct)
The bacteria mutate rapidly in response to the antibiotic
The bacteria are killed by the antibiotic

Which microbial sources can produce antibiotics?

Bacteria (B) Signup and view all the answers

What is the role of the CLSI in antibiotic testing?

To standardize culture and sensitivity testing methods (C) Signup and view all the answers

Which type of antibiotics require a bacterial strain to be inhibited for their effectiveness?

Bacteriostatic antibiotics (D) Signup and view all the answers

What role does folic acid play in bacterial DNA production?

Folic acid is a precursor molecule for DNA production (C) Signup and view all the answers

What characterizes an 'Intermediate' bacterial strain in terms of antibiotic sensitivity?

'Intermediate' strains are moderately susceptible to the antibiotic (C) Signup and view all the answers

Which of the following is true regarding the mechanism of action of aminoglycosides?

They inhibit protein synthesis by binding to the 30S ribosomal subunit. (B) Signup and view all the answers

Which of the following statements about quinolones is correct?

They target bacterial DNA gyrase and topoisomerase IV, inhibiting DNA replication. (A) Signup and view all the answers

What is the primary mechanism of action of sulfonamides?

They are competitive inhibitors of $p$-aminobenzoic acid (PABA) in folic acid synthesis. (A) Signup and view all the answers

Which of the following statements about the Kirby-Bauer antibiotic testing method is correct?

It measures the diameter of the zone of inhibition around an antibiotic-impregnated disk to determine susceptibility. (B) Signup and view all the answers

Which of the following statements about bacteriostatic antibiotics is correct?

They inhibit bacterial growth and replication but do not kill the bacteria. (B) Signup and view all the answers

Which of the following is a common mechanism of antibiotic resistance in bacteria?

All of the above. (D) Signup and view all the answers

Which of the following statements about antibiotic resistance is correct?

Antibiotic resistance can spread between different bacterial species through horizontal gene transfer. (A) Signup and view all the answers

What is the primary function of the Clinical and Laboratory Standards Institute (CLSI)?

To develop and publish guidelines for antibiotic susceptibility testing and interpretation. (A) Signup and view all the answers

Which of the following statements about macrolide antibiotics is correct?

They inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit. (B) Signup and view all the answers

Which of the following is a possible consequence of inappropriate or overuse of antibiotics?