22 Questions
Which structure is responsible for the movement of microtubules in an axoneme?
Dynein
Which drug binds to tubulin and inhibits microtubule assembly?
Colchicine
What is the function of nexins in an axoneme?
Anchoring MTs
Which of the following is NOT a main type of cytoskeletal element?
Myosin
Which of the following is responsible for the continuous assembly and disassembly of microfilaments?
Actin Binding Proteins
Which type of myosin is associated with non-muscle cells and is involved in cell motility?
Myosin II
Which type of cytoskeletal component has a diameter of 10 nm?
Intermediate Filaments
What is the main function of the Arp 2/3 complex?
F-actin branching
Which end of F-actin grows at a faster rate?
Plus (+) end
What is the molecular basis of movement in cilia and flagella?
Microtubules
Which protein is a key intermediate filament protein of the cytoskeleton in cardiac and skeletal muscle?
Desmin
Which type of cell tumors can be identified using specific antibodies for immunohistochemistry?
Carcinomas
What is the basic structural unit of microtubules?
Tubulin heterodimer
Which type of microtubule-dependent ATPases carry cargo outward towards the plus end of microtubules?
Kinesins
Which motor protein is present in all cell types and interacts with F-actin to generate force or translocate molecules and organelles?
Myosin II
Which class of myosin contains traditional or conventional myosins such as skeletal and heart muscle myosin, smooth muscle myosin, and non-muscle myosin?
Myosin II
Which domain of myosin heavy chains (MHC) contains the ATPase activity?
Motor (head) domain
What happens to myosin activity when the regulatory light chains (RLC) are phosphorylated?
Increases ATPase activity in MHC motor domain
Which of the following is true about the contractile ring during mitosis?
It is connected to the cell membrane
What is the main function of intermediate filaments?
To provide mechanical support and structural integrity to the cell
Which of the following is true about Myosin I?
It moves along microfilaments toward the minus end
What is the consequence of F-actin polymerization being faster than sliding of F-actin toward the minus ends?
The cell moves forward
Test your knowledge on contractile assemblies of microfilaments and conventional non-muscle myosin II (NM II) with this quiz. Explore examples such as F-actin, Vinculin, Cadherin, and Myosin as you learn about the formation of a contractile ring during telophase of mitosis. Discover how microfilaments and NM II work together to cause constriction and cleavage of cells.
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