Contractile Assemblies and Non-Muscle Myosin II Quiz

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Questions and Answers

Which structure is responsible for the movement of microtubules in an axoneme?

  • Dynein (correct)
  • Nexins
  • Centrioles
  • Basal bodies

Which drug binds to tubulin and inhibits microtubule assembly?

  • Vincristine
  • Taxol
  • Colchicine (correct)
  • Vinblastine

What is the function of nexins in an axoneme?

  • Bending MTs
  • Movement
  • Structural integrity
  • Anchoring MTs (correct)

Which of the following is NOT a main type of cytoskeletal element?

<p>Myosin (A)</p> Signup and view all the answers

Which of the following is responsible for the continuous assembly and disassembly of microfilaments?

<p>Actin Binding Proteins (D)</p> Signup and view all the answers

Which type of myosin is associated with non-muscle cells and is involved in cell motility?

<p>Myosin II (A)</p> Signup and view all the answers

Which type of cytoskeletal component has a diameter of 10 nm?

<p>Intermediate Filaments (C)</p> Signup and view all the answers

What is the main function of the Arp 2/3 complex?

<p>F-actin branching (D)</p> Signup and view all the answers

Which end of F-actin grows at a faster rate?

<p>Plus (+) end (B)</p> Signup and view all the answers

What is the molecular basis of movement in cilia and flagella?

<p>Microtubules (C)</p> Signup and view all the answers

Which protein is a key intermediate filament protein of the cytoskeleton in cardiac and skeletal muscle?

<p>Desmin (B)</p> Signup and view all the answers

Which type of cell tumors can be identified using specific antibodies for immunohistochemistry?

<p>Carcinomas (A)</p> Signup and view all the answers

What is the basic structural unit of microtubules?

<p>Tubulin heterodimer (B)</p> Signup and view all the answers

Which type of microtubule-dependent ATPases carry cargo outward towards the plus end of microtubules?

<p>Kinesins (A)</p> Signup and view all the answers

Which motor protein is present in all cell types and interacts with F-actin to generate force or translocate molecules and organelles?

<p>Myosin II (C)</p> Signup and view all the answers

Which class of myosin contains traditional or conventional myosins such as skeletal and heart muscle myosin, smooth muscle myosin, and non-muscle myosin?

<p>Myosin II (C)</p> Signup and view all the answers

Which domain of myosin heavy chains (MHC) contains the ATPase activity?

<p>Motor (head) domain (A)</p> Signup and view all the answers

What happens to myosin activity when the regulatory light chains (RLC) are phosphorylated?

<p>Increases ATPase activity in MHC motor domain (A)</p> Signup and view all the answers

Which of the following is true about the contractile ring during mitosis?

<p>It is connected to the cell membrane (C)</p> Signup and view all the answers

What is the main function of intermediate filaments?

<p>To provide mechanical support and structural integrity to the cell (A)</p> Signup and view all the answers

Which of the following is true about Myosin I?

<p>It moves along microfilaments toward the minus end (B)</p> Signup and view all the answers

What is the consequence of F-actin polymerization being faster than sliding of F-actin toward the minus ends?

<p>The cell moves forward (B)</p> Signup and view all the answers

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