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Questions and Answers
What is the primary mechanism of action of Levonorgestrel (Plan B)?
What is the primary mechanism of action of Levonorgestrel (Plan B)?
What is the main difference between Ulipristal (Ella) and Levonorgestrel (Plan B)?
What is the main difference between Ulipristal (Ella) and Levonorgestrel (Plan B)?
What type of IUD does not release hormones?
What type of IUD does not release hormones?
What is a common side effect of Mirena and Skyla IUDs?
What is a common side effect of Mirena and Skyla IUDs?
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What is the primary advantage of IUDs?
What is the primary advantage of IUDs?
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Why may some women not have access to IUDs?
Why may some women not have access to IUDs?
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What is a potential complication of IUD placement?
What is a potential complication of IUD placement?
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What is a characteristic of the Paragard IUD?
What is a characteristic of the Paragard IUD?
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Why is screening for STIs performed during IUD placement?
Why is screening for STIs performed during IUD placement?
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What is the similarity in the incidence of pelvic inflammatory disease between women with IUCs and women without them?
What is the similarity in the incidence of pelvic inflammatory disease between women with IUCs and women without them?
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What is the contraindication for latex-based condoms?
What is the contraindication for latex-based condoms?
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What is the primary function of the barrier methods of birth control?
What is the primary function of the barrier methods of birth control?
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What is the disadvantage of the female condom compared to the male condom?
What is the disadvantage of the female condom compared to the male condom?
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What is the recommended replacement interval for diaphragms?
What is the recommended replacement interval for diaphragms?
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What is the failure rate of the diaphragm within a year?
What is the failure rate of the diaphragm within a year?
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What is the advantage of using male condoms?
What is the advantage of using male condoms?
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What should be checked after a woman gives birth, has a miscarriage or abortion, or gains or loses more than 10 pounds?
What should be checked after a woman gives birth, has a miscarriage or abortion, or gains or loses more than 10 pounds?
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What can weaken the integrity of latex-based condoms?
What can weaken the integrity of latex-based condoms?
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What is a common side effect of using hormonal contraceptives containing progestin?
What is a common side effect of using hormonal contraceptives containing progestin?
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Who should not use combined oral contraceptive pills?
Who should not use combined oral contraceptive pills?
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What is a potential health risk associated with using hormonal contraceptives?
What is a potential health risk associated with using hormonal contraceptives?
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What is a benefit of using combined oral contraceptive pills?
What is a benefit of using combined oral contraceptive pills?
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What should you do if you miss a dose of combined oral contraceptive pills?
What should you do if you miss a dose of combined oral contraceptive pills?
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What is a characteristic of extended cycling combined oral contraceptive pills?
What is a characteristic of extended cycling combined oral contraceptive pills?
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Why are combined oral contraceptive pills not suitable for people who forget to take their pills every day?
Why are combined oral contraceptive pills not suitable for people who forget to take their pills every day?
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What is a contraindication for combined oral contraceptive pills?
What is a contraindication for combined oral contraceptive pills?
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What is not a benefit of using combined oral contraceptive pills?
What is not a benefit of using combined oral contraceptive pills?
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What percentage of infertility cases involve combined male and female factors?
What percentage of infertility cases involve combined male and female factors?
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What is the duration of well-timed intercourse required to define infertility in women over 35 years old?
What is the duration of well-timed intercourse required to define infertility in women over 35 years old?
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What is the risk of multiple gestation with clomiphene citrate compared to spontaneous pregnancies?
What is the risk of multiple gestation with clomiphene citrate compared to spontaneous pregnancies?
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What percentage of infertility cases have unknown causes?
What percentage of infertility cases have unknown causes?
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What is the common first-line medication to induce ovulation?
What is the common first-line medication to induce ovulation?
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When is clomiphene citrate usually started?
When is clomiphene citrate usually started?
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What lifestyle factor impairs fertility in both sexes?
What lifestyle factor impairs fertility in both sexes?
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What is the percentage of infertility cases related to male factors?
What is the percentage of infertility cases related to male factors?
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What is the risk of miscarriage or ectopic pregnancy with clomiphene citrate compared to spontaneous pregnancies?
What is the risk of miscarriage or ectopic pregnancy with clomiphene citrate compared to spontaneous pregnancies?
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What is the primary mechanism of action of Human menopausal gonadotropin (Pergonal)?
What is the primary mechanism of action of Human menopausal gonadotropin (Pergonal)?
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What is a possible risk associated with Human menopausal gonadotropin (Pergonal) treatment?
What is a possible risk associated with Human menopausal gonadotropin (Pergonal) treatment?
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What is the primary purpose of Intrauterine insemination (IUI)?
What is the primary purpose of Intrauterine insemination (IUI)?
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What is a possible outcome of In Vitro Fertilization (IVF)?
What is a possible outcome of In Vitro Fertilization (IVF)?
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What is the primary mechanism of action of Gamete intrafallopian transfer (GIFT)?
What is the primary mechanism of action of Gamete intrafallopian transfer (GIFT)?
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What is a common procedure used in Intracytoplasmic sperm injection (ICSI)?
What is a common procedure used in Intracytoplasmic sperm injection (ICSI)?
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What is a possible option for treatment of infertility due to male factors?
What is a possible option for treatment of infertility due to male factors?
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What is a possible option for treatment of infertility due to ovarian factors?
What is a possible option for treatment of infertility due to ovarian factors?
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What is a possible option for treatment of infertility when the woman is unable to carry a pregnancy?
What is a possible option for treatment of infertility when the woman is unable to carry a pregnancy?
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What is a disadvantage of using the female condom compared to the male condom?
What is a disadvantage of using the female condom compared to the male condom?
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What is a characteristic of the diaphragm?
What is a characteristic of the diaphragm?
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What is a potential problem with using latex-based condoms?
What is a potential problem with using latex-based condoms?
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What is an advantage of using male condoms?
What is an advantage of using male condoms?
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How often should diaphragms be replaced?
How often should diaphragms be replaced?
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When should the fit of a diaphragm be checked?
When should the fit of a diaphragm be checked?
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What is a characteristic of male condoms?
What is a characteristic of male condoms?
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What is the primary benefit of using condoms for contraception?
What is the primary benefit of using condoms for contraception?
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Which of the following is a consideration for patients who don't want their partners to know they're using contraception?
Which of the following is a consideration for patients who don't want their partners to know they're using contraception?
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What is the advantage of hormonal methods of contraception?
What is the advantage of hormonal methods of contraception?
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Which of the following is a disadvantage of hormonal methods of contraception?
Which of the following is a disadvantage of hormonal methods of contraception?
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What is the importance of access to contraception?
What is the importance of access to contraception?
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What is a common side effect of using hormonal contraceptives containing progestin?
What is a common side effect of using hormonal contraceptives containing progestin?
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What is the best method of contraception for a patient?
What is the best method of contraception for a patient?
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What is a contraindication for combined oral contraceptive pills?
What is a contraindication for combined oral contraceptive pills?
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Why is it beneficial to have two years between pregnancies?
Why is it beneficial to have two years between pregnancies?
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What should you do if you miss more than one dose of combined oral contraceptive pills?
What should you do if you miss more than one dose of combined oral contraceptive pills?
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What is a benefit of using combined oral contraceptive pills?
What is a benefit of using combined oral contraceptive pills?
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What is a characteristic of extended cycling combined oral contraceptive pills?
What is a characteristic of extended cycling combined oral contraceptive pills?
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Why are combined oral contraceptive pills not suitable for people who forget to take their pills every day?
Why are combined oral contraceptive pills not suitable for people who forget to take their pills every day?
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What is the recommended time frame for placing a contraceptive sponge in the vagina?
What is the recommended time frame for placing a contraceptive sponge in the vagina?
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What is the failure rate of the contraceptive sponge in women who have given birth?
What is the failure rate of the contraceptive sponge in women who have given birth?
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What is a potential health risk associated with using hormonal contraceptives?
What is a potential health risk associated with using hormonal contraceptives?
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What is a common complication associated with tubal ligation?
What is a common complication associated with tubal ligation?
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What is the primary advantage of vasectomy compared to bilateral tubal ligation?
What is the primary advantage of vasectomy compared to bilateral tubal ligation?
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What is the primary mechanism of action of vasectomy?
What is the primary mechanism of action of vasectomy?
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What is the recommended follow-up care after a vasectomy?
What is the recommended follow-up care after a vasectomy?
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What is the primary advantage of surgical methods of birth control compared to barrier methods?
What is the primary advantage of surgical methods of birth control compared to barrier methods?
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What is the primary action of Progestin-only pills on the cervix?
What is the primary action of Progestin-only pills on the cervix?
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What is a side effect of Progestin-only pills?
What is a side effect of Progestin-only pills?
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How often must Progestin-only pills be taken to be effective?
How often must Progestin-only pills be taken to be effective?
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What is a risk associated with pregnancy while using Progestin-only pills?
What is a risk associated with pregnancy while using Progestin-only pills?
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How is the Contraceptive Ring used?
How is the Contraceptive Ring used?
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What is the primary advantage of the contraceptive patch?
What is the primary advantage of the contraceptive patch?
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What is the primary benefit of using the contraceptive implant?
What is the primary benefit of using the contraceptive implant?
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What is the primary limitation of using the contraceptive injection?
What is the primary limitation of using the contraceptive injection?
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What is the primary indication for using emergency contraception?
What is the primary indication for using emergency contraception?
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What is the primary difference between the contraceptive patch and the contraceptive injection?
What is the primary difference between the contraceptive patch and the contraceptive injection?
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What is the primary advantage of using the contraceptive implant compared to the contraceptive injection?
What is the primary advantage of using the contraceptive implant compared to the contraceptive injection?
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What is the primary limitation of using the contraceptive patch?
What is the primary limitation of using the contraceptive patch?
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Study Notes
Contraception
- Hormonal methods: need a prescription, not effective against STIs, and may have side effects like nausea, breast tenderness, and mood swings.
- Progestin methods: may cause irregular bleeding, and have adverse reactions like blood clots.
- Contraindications: migraine with aura, hypertension, history of DVT, PE, stroke, and smokers over 35.
- Not suitable for breastfeeding mothers.
Combined Oral Contraceptive Pills
- Contain 21 hormone-containing pills followed by 7 placebo pills.
- Extended cycling: 84 active pills, 7 days placebo.
- Can help with PCOS, acne, menstrual cramping, and heavy bleeding.
- Missed dose: take a pill as soon as you remember, then take the next dose at the regular time.
- If you miss more than one, take the next dose, but use other birth control for 7 days.
- More effective in women who weigh over 165 pounds.
Emergency Contraception
- Levonorgestrel (PlanB): available over the counter or by prescription, more effective when taken within 72 hours of unprotected intercourse.
- Works by preventing ovulation, does not affect an established pregnancy.
- Must be used within 72 hours of unprotected sex.
- Ulipristal (Ella): available by prescription only, works as a progestin blocker, and may affect an existing pregnancy.
- May be used within 120 hours of unprotected intercourse.
Intrauterine Devices (IUDs)
- Types: copper (Paragard) and progestin-releasing (Mirena and Skyla).
- T-shaped device inserted into the uterus, works by thinning the lining of the uterus and creating an environment not good for sperm.
- Hormone-releasing IUDs also prevent ovulation.
- Does not interrupt a pregnancy or cause abortion.
- Advantages: no chance of user error, completely reversible, and long-acting.
- Disadvantages: initially expensive, may not be accessible to some women, and may cause heavier bleeding and cramping.
Barrier Methods of Birth Control
- Male Condoms:
- Consist of a sheath that goes over the penis, provide a barrier that prevents semen from entering the female reproductive tract.
- Advantages: widely available, inexpensive, protect against STIs, allow male partner to be active in family planning.
- Disadvantages: adherence is poor, breakage or slippage may occur, latex allergy is a contraindication, and can degrade over time.
- Female Condom:
- Contains two semi-rigid rings attached to the opening of a nitrile tube.
- Placement is similar to a tampon, new female condom should be used with each episode of rectal or vaginal sex.
- Expensive and more cumbersome than a male condom.
- Diaphragm:
- Flexible saucer that is placed into the vagina to cover the cervix.
- Does not protect against STIs, has a 12% failure rate within a year.
- Fit should be checked if the woman gives birth, has a miscarriage or abortion, or gains or loses more than 10 pounds.
Fertility and Infertility
- Infertility: lack of pregnancy after 12 months of well-timed intercourse (6 months if the woman is over 35 years old).
- May involve recurrent spontaneous abortion (miscarriage).
- Infertility may be related to male factors (35%), female factors (35%), and combined male and female factors (20%).
- In about 10% of infertility cases, the cause is unknown.
- Overweight or underweight women may be counseled to lose or gain weight to induce ovulation.
Fertility Treatment
- Clomiphene:
- Selective estrogen receptor modulator, common first-line medication to induce ovulation.
- Started 5 days after the start of menses, the risk of miscarriage or ectopic pregnancy is the same as with spontaneous pregnancies.
- The risk of multiple gestation is increased 7% with clomiphene citrate compared to spontaneous pregnancies.
- Human Menopausal Gonadotropin (Pergonal):
- Self-administered IM injection given daily until ultrasound reveals a mature ovarian follicle.
- Directly stimulates ovaries, recommend intercourse every other day for 1 week starting day 5 of beginning medication.
- Patient required to come in for multiple office visits per cycle for labs and ultrasound.
- Risk of ovarian hyperstimulation, serious cases require hospitalization.
- The risk of multiple gestation is 10-20% (majority are twin gestation).
Artificial Reproductive Technology (ART)
- Multiple modalities exist, and may sometimes be combined to increase odds:
- Intrauterine Insemination (IUI):
- Sperm is washed and then introduced into the upper uterine cavity.
- In Vitro Fertilization (IVF):
- Used to treat infertility due to tubal factors, severe male factors, uterine, or ovarian factors.
- Ovaries are stimulated and eggs retrieved by ultrasound-guided follicle aspiration and then mixed with cleaned sperm.
- Successful fertilization can be identified after 17 hours and transplanted into the uterus or frozen.
- Gamete Intrafallopian Transfer (GIFT):
- Sperm and eggs are combined and then placed in the fallopian tube for fertilization via laparoscopy.
- Requires general anesthesia and surgical intervention.
- Intracytoplasmic Sperm Injection (ICSI):
- Sperm is retrieved from the epididymis using a needle through the skin, and a single sperm cell is isolated and injected into an egg.
- Donor Sperm:
- Sperm is obtained from a donor, washed and used for fertilization either with IUI or IVF procedures.
- Donor Oocytes:
- Eggs are obtained from donors and combined with sperm (male partner's or donors) in IVF.
- Surrogacy (Gestational Carrier):
- Can use couple's or donor egg/sperm.
Intrauterine Contraception (IUC)
- IUCs have a small risk of perforating the uterus during insertion.
- The incidence of pelvic inflammatory disease is the same for women with IUCs as for women without them.
Barrier Methods of Birth Control
-
Male Condoms
- Consist of a sheath that goes over the penis
- Provide a barrier that prevents semen from entering the female reproductive tract
- Most are latex-based; non-latex are made from animal intestine
- Advantages: widely available, inexpensive, protect against STIs, allow male partner to be active in family planning
- Disadvantages: poor adherence, breakage or slippage, latex allergy, degrade over time
-
Female Condom
- Contains two semi-rigid rings attached to a nitrile tube
- Placement is similar to a tampon
- A new female condom should be used with each episode of rectal or vaginal sex
- Expensive and more cumbersome than a male condom
-
Diaphragm
- A flexible saucer that is placed into the vagina to cover the cervix
- Does not protect against STIs
- 12% failure rate within a year
- Fit should be checked after childbirth, miscarriage, or abortion, or if weight changes by more than 10 pounds
- Should be replaced every 2 years
-
Contraceptive Sponge
- A spermicide-infused, foam disk that fits over the cervix
- Available over the counter
- 12% failure rate in women who have never given birth, 24% failure rate in women who have given birth
- Should be placed up to 24 hours before sexual intercourse and stay in no more than 30 hours
Contraception
-
Access to Contraception
- Increases educational and economic opportunities for men and women
- Reduces maternal mortality/morbidity
- Decreases infant mortality/morbidity
- Reduces stress on families
- Prevents unsafe abortions
-
Contraception Considerations
- The best method is the one that is accessible, affordable, and can be used consistently
- Methods that don't invite user error have lower failure rates
- Only condoms prevent infection while preventing pregnancy
Hormonal Methods
-
How they Work
- Suppress ovulation, thicken cervical mucus, and thin the uterine lining
-
Effectiveness
- In a perfect world, failure rate is 0.3%
- In reality, failure rate is 3-8% depending on the method
-
Advantages
- No effect on future fertility, relieves PMS, lighter periods, no impact on spontaneity, can be used to treat PCOS, reduces acne
-
Disadvantages
- Need a prescription, not effective against STIs, side effects, adverse reactions, contraindications
Surgical Methods
-
Tubal Ligation
- Most common method around the world and 2nd most common in the US
- Can be performed outpatient or during a C-section
- Surgical procedure with associated risks
- Failure rate is 0.5%
-
Vasectomy
- Safer and cheaper than bilateral tubal ligation, but fewer men have the procedure
- Cutting the vas deferens prevents sperm from exiting the male body
- Performed in an office under local anesthesia
- Permanent procedure, but reversal is possible
Contraceptive Patch
-
How it Works
- A patch containing estrogen and progestin applied weekly for 3 weeks
- Followed by a patch-free week, which causes a withdrawal bleed
-
Failure Rate
- 9% with normal BMI, higher with obesity
-
Not for
- Breastfeeding mothers
Contraceptive Injection (Depo-Provera)
-
How it Works
- A progestin-only injection given every 13 weeks until pregnancy is desired
-
Failure Rate
- 6%
-
Concerns
- Weight gain, used with breastfeeding mothers may diminish milk production
Contraceptive Implant (LARC)
-
How it Works
- A 4-cm rod of non-estrogen etonogestrel is inserted under the skin of the inner upper arm
- Approved for use for 3 years
-
Failure Rate
- Less than 0.05%
-
Concerns
- Unscheduled bleeding, removal can be difficult, leaves scars
Emergency Contraception
-
Options
- Medication or a copper intrauterine contraception (IUC)
-
Progestin-only Pills (POPs)
- Contain only progestin
- Safe for breastfeeding mothers
- Failure rate is 9%
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Description
This quiz covers the side effects and contraindications of various contraception methods, including those containing progestin. Learn about the risks and precautions to take.