Constipation Relief and IBD Treatments

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Questions and Answers

What is the recommended glycerin suppository dosage for children under 6 years old?

1 g (correct)

3 g

2 g

4 g

Which of the following is a stimulant laxative mentioned?

Glycerin suppository

Prucalopride

Caster oil formulations (correct)

Polyethylene Glycol

What dosage of Polyethylene Glycol is used in bulk form?

40 g

100 g

70 g (correct)

500 g

Higher doses of Polyethylene Glycol are used for which procedure?

Whole bowel irrigation before colonoscopy Signup and view all the answers

Which of the following is NOT mentioned as a dosage form for glycerin?

Ointment Signup and view all the answers

What is the recommended dosage of sulfate (Epsom salt) for a morning dose?

5–15 g Signup and view all the answers

How much water is advised to dissolve 10–15 g of sodium sulfate (Glauber’s salt)?

150–200 ml Signup and view all the answers

What form is magnesium hydroxide typically taken in?

8% W/W suspension (milk of magnesia) Signup and view all the answers

What is the dosage of magnesium hydroxide recommended in the content?

30 ml Signup and view all the answers

Which of the following is NOT a recommended preparation for morning intake according to the content?

Sodium bicarbonate Signup and view all the answers

What is the primary purpose of corticosteroids in the treatment of IBD?

To induce treatment for moderate to severe IBD Signup and view all the answers

What is the recommended dosage range of prednisolone for treating Ulcerative Colitis?

40-60 mg Signup and view all the answers

When should oral corticosteroids be taken for optimal effectiveness?

With breakfast or milk in the morning Signup and view all the answers

Why might it be beneficial to take corticosteroids in the morning?

Aligns with the body's natural steroid production cycle Signup and view all the answers

What is a necessary consideration for patients when taking oral corticosteroids?

They should take it with meals to reduce side effects Signup and view all the answers

What is the preferred storage method for biologic immunosuppressants like Etanercept?

In a refrigerator Signup and view all the answers

Which drug is classified as a biologic immunosuppressant used in severe conditions?

Etanercept Signup and view all the answers

What form of administration is used for Etanercept?

Subcutaneous administration Signup and view all the answers

What is the dosage available for Etanercept in vials?

25mg and 50mg Signup and view all the answers

What is one of the primary uses of Nitroglycerin 0.4% ointment?

For anal fissure and fistula Signup and view all the answers

What role do anti-inflammatory agents like Etanercept play in IBD?

They reduce inflammation Signup and view all the answers

Which of the following compounds is used in ointment form for treating anal conditions?

Diltiazem 2% ointment Signup and view all the answers

Which compound is NOT mentioned in relation to treating anal fissures?

Amlodipine 5mg Signup and view all the answers

Which medication mentioned is primarily a topical ointment?

Diltiazem Signup and view all the answers

What is the common application area for Nitroglycerin 0.4% ointment?

Rectal area Signup and view all the answers

Study Notes

Glycerin Suppositories

Glycerin suppositories are used for constipation relief in both children and adults.
Children under ６ years old receive 1g, while adults receive 2g.

Laxatives

Prucalopride: Available as a laxative.
Castor Oil Formulations:
- Available in different forms like emulsion, capsules, and suppositories.
- Stimulant laxative.
Polyethylene Glycol (PEG):
- Sachet and powder forms available.
- Used in higher doses for whole bowel irrigation before colonoscopy.
Magnesium Sulfate (Epsom Salt):
- 5–15g dissolved in 150–200ml water, taken in the morning.
Magnesium Hydroxide (Milk of Magnesia):
- 30ml of 8% W/W suspension.
Sodium Sulfate (Glauber’s Salt):
- 10–15g dissolved in 150–200ml water, taken in the morning.

Anti-Inflammatory Agents in IBD

Corticosteroids:
- Used to induce treatment of moderate to severe IBD and as the first-line treatment for Ulcerative Colitis (UC).
- Prednisolone (high-dose oral tablet) is commonly prescribed in doses of 40-60mg.
- Should be taken with meals, preferably in the morning with milk or breakfast.
- Store in the refrigerator.

Other Biologic Immunosuppressants for IBD

Etanercept (Enbrel, Altebrel):
- Available in vials (25mg and 50mg), and prefilled syringes (50mg).
- Administered subcutaneously.
- Not typically a first-line treatment option.
- Store in the refrigerator.

Other Compounds

Nitroglycerin 0.4% ointment (Rectoderm®):
- Used for anal fissures and fistulas.
Diltiazem 2% ointment:
- Also used for anal fissures and fistulas.

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Description

This quiz covers various treatments for constipation, including glycerin suppositories, laxatives, and anti-inflammatory agents used in Inflammatory Bowel Disease (IBD). Learn about dosages for different age groups and the forms in which these medications are available. Test your knowledge on these important gastrointestinal treatments.