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Questions and Answers
What is the result of a sharp drop in population size?
What is the result of a sharp drop in population size?
What is the formula to calculate the final heterozygosity?
What is the formula to calculate the final heterozygosity?
What is the effect of a small population on heterozygosity?
What is the effect of a small population on heterozygosity?
What is the rate of allele loss in a population?
What is the rate of allele loss in a population?
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What is the consequence of the founder effect?
What is the consequence of the founder effect?
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What is the effect of population size on the rate of allele loss?
What is the effect of population size on the rate of allele loss?
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What is the result of a small population becoming isolated?
What is the result of a small population becoming isolated?
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What is the relationship between population size and genetic diversity?
What is the relationship between population size and genetic diversity?
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What is the formula to calculate the initial heterozygosity?
What is the formula to calculate the initial heterozygosity?
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What is the effect of a bottleneck on a population's gene pool?
What is the effect of a bottleneck on a population's gene pool?
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Study Notes
Population Genetics
- Population genetics is the study of genetic variability by describing changes in allele frequency for a particular trait over time and analyzing the causes of those changes.
- It is the application of Mendel's laws and other genetic principles to entire populations of organisms instead of just individuals.
Definitions
- Phenotype: describes all traits of an individual concerning its morphology, physiology, ecological relationships, and behavior.
- Genotype: is the description of the complete set of genes that an individual inherits from its parents.
- Gene: the basic physical and functional unit of heredity, passing information from one generation to the next.
- Allele: any of the alternative forms of a gene that can exist at a single locus.
- Allele frequency: the proportion of all alleles of that gene in the population that are specifically this type.
- Genotype frequency: the frequency of a given genotype in a population.
The Hardy-Weinberg Principle
- States that sexual reproduction does not reduce genetic variation generation after generation; on the contrary, the amount of variation remains constant if no disturbing forces are acting against it.
- Assumes:
- Sexual reproduction
- Non-overlapping generations
- Random mating
- Very large population size
- Negligible migration
- No natural selection
- No mutations
Reproduction and Mating Systems
- Inbreeding coefficient (F): measures the reduction of heterozygosity
- H: actual frequency of heterozygotes in the population
- H0: expected number of heterozygotes under random mating
Forces Shaping Genetic Diversity
- Mutation: the ultimate source of variation, may be caused by spontaneous mutation or damage by radiation or chemical mutagens
- Migration: increases diversity, rate of change in gene frequency is proportional to the difference in frequency between the recipient population and the average of the donor populations
- Recombination: generates new combinations of existing diversity, does not create new diversity
- Selection: acts on the inherited ability of organisms to survive and reproduce, leading to an increase in superior genotypes
Genetic Drift
- Homozygosity: fixation and loss of alleles
- Subpopulation differentiation: leads to genetic drift
- Bottleneck: develops when the population size sharply drops, leading to loss of alleles
- Founder effect: occurs when a few individuals colonize and become established in a new environment, leading to genetic drift
- Population size: affects genetic diversity, heterozygosity declines with smaller population size
- Allele loss: occurs at a rate dependent on population size and allele frequencies
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Description
Test your understanding of the fundamental concepts of genetic diversity, including the Hardy-Weinberg principle, reproduction and mating systems, and forces shaping genetic diversity. This quiz covers the basics of population genetics and its importance in conservation of genetic resources.