Connective Tissue Overview

Epithelial, muscular, nervous, and connective tissue.

Fibroblasts, adipocytes, plasma cells, mast cells, and macrophages.

Fibroblasts are important for the synthesis of collagen fibers and ground substances.

<p>Unilocular adipocytes have a single large lipid droplet, while multilocular adipocytes contain multiple smaller droplets.</p> Signup and view all the answers

<p>The ECM provides structural and biochemical support to surrounding cells.</p> Signup and view all the answers

<p>The rough endoplasmic reticulum is significant for the synthesis of proteins, including collagen.</p> Signup and view all the answers

<p>Connective tissue integrates with epithelial, muscular, and nervous tissues to support and facilitate their functions.</p> Signup and view all the answers

<p>Connective tissue is derived from the mesoderm of embryonic germ layers.</p> Signup and view all the answers

<p>Multilocular adipocytes have a small spherical morphology, typically measuring 15-25 µm.</p> Signup and view all the answers

<p>Unilocular adipocytes have a flattened nucleus that is displaced to the periphery, while multilocular adipocytes have a round nucleus that is centrally located.</p> Signup and view all the answers

<p>The numerous mitochondria in multilocular adipocytes are crucial for thermogenesis and energy expenditure.</p> Signup and view all the answers

<p>Plasma cells are responsible for producing antibodies, playing a critical role in humoral immunity.</p> Signup and view all the answers

<p>Mast cells contain metachromatic granules that include histamine, heparin, and chemotactic factors.</p> Signup and view all the answers

<p>Monocytes migrate from the bloodstream and differentiate into macrophages through a process called diapedesis.</p> Signup and view all the answers

<p>Plasma cells exhibit intense basophilic staining due to a well-developed rough endoplasmic reticulum (rER).</p> Signup and view all the answers

<p>Unilocular adipocytes are surrounded by a dense network of capillaries and collagen type III (reticular fibers).</p> Signup and view all the answers

Small, spherical cells (15-25 µm) with numerous lipid droplets of varying sizes. Round nucleus centrally located. Rich in mitochondria and cytochrome. Found predominantly in birds, rodents, and newborn mammals (thyroid glands and renal hilus).

Large, spherical to polyhedral cells (25-100 µm) with a single, large lipid droplet (lipoblast). Flattened nucleus displaced to the periphery (signet ring). Stabilized by microfilaments. Color determined by carotenoids.

Derived from hematopoietic stem cells, also known as histiocytes. Circulate as monocytes and differentiate into macrophages (diapedesis) . Exist as resident macrophages in specific organs (Kupffer cells in liver, Langerhans cells in skin, dust cells in lungs).

Large, ovoid cells (20-30 µm) in loose connective tissue. Centrally located nucleus with ellipsoid shape. Basophilic cytoplasm. Numerous variable-sized metachromatic granules (0.3-0.8 µm). Contain histamine, heparin, and chemotactic factors (ECF and NCF). Express IgE receptors involved in type I hypersensitivity.

Differentiated B-lymphocytes (humoral immunity). Large, ovoid cells (20 µm). Eccentrically located nucleus with heterochromatin concentrated in peripheral clumps (clock face, spoke wheel, or cartwheel). Intensely basophilic cytoplasm with well-developed rER. Found in the lamina propria.

One of the four basic animal tissues, responsible for supporting and connecting other tissues. It plays a crucial role in integrating different tissues for physiological functions.

A type of connective tissue that forms the framework of the body and supports various organs. Typically found in the mesoderm of the embryonic germ layers, it consists of cells and an extracellular matrix.

Cells that are responsible for the synthesis of fibers (collagen and elastic) and ground substance in connective tissue proper. They have a fusiform shape with cytoplasmic projections and a prominent nucleus.

Cells specialized for the storage of lipids (fats). They can be classified into two types: multilocular (brown) and unilocular (white) adipocytes.

The non-cellular component of connective tissue proper. It provides structural support and facilitates communication between cells. It is made up of fibers and ground substance.

The non-fibrous component of the extracellular matrix. It fills the spaces between cells and fibers and is composed of glycoproteins, proteoglycans, and hyaluronic acid.

Structural components of the extracellular matrix that provide strength, support, and elasticity to connective tissue. Collagen fibers are strong and flexible, while elastic fibers can stretch and recoil.