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Congenital CMV Infection Overview

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Questions and Answers

Which symptom is not associated with CMV infection in immunocompetent adults?

Lethargy

Abnormal lymphocytes in peripheral blood smears

Intractable colitis (correct)

Fever

What is a method used for the laboratory diagnosis of CMV infection?

Culturing in shell vials with immunofluorescent antibody (correct)

Western blot for viral proteins

Mass spectrometry for viral DNA

ELISA for viral antibodies

Which statement about CMV retinitis treatment is accurate?

Valganciclovir is not effective against CMV retinitis

Valganciclovir and Ganciclovir are used for treating CMV retinitis (correct)

Cidofovir is used for CMV pneumonia treatment

Ganciclovir is not recommended for CMV retinitis in AIDS patients

What is a characteristic feature of CMV inclusion bodies in giant cells?

They are intranuclear and oval with an owl's-eye appearance (D) Signup and view all the answers

In which patient population does CMV commonly cause hepatitis and pneumonitis?

Immunosuppressed patients like transplant recipients (D) Signup and view all the answers

Which method is used to detect CMV nucleic acids in tissues or body fluids?

Polymerase chain reaction (PCR)-based assays (D) Signup and view all the answers

What does CMV Antigenemia measure within blood leukocytes?

pp65 protein using immunofluorescence assay (C) Signup and view all the answers

What treatment is effective against CMV retinitis in AIDS patients?

Valganciclovir (C) Signup and view all the answers

What type of infection can CMV cause in AIDS patients that may lead to blindness?

Retinitis (A) Signup and view all the answers

Which method is used to identify inclusion bodies in CMV infections?

Fluorescent-antibody & histologic staining of inclusion bodies in giant cells (C) Signup and view all the answers