Congenital CMV Infection Overview
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Questions and Answers

Which symptom is not associated with CMV infection in immunocompetent adults?

  • Lethargy
  • Abnormal lymphocytes in peripheral blood smears
  • Intractable colitis (correct)
  • Fever

What is a method used for the laboratory diagnosis of CMV infection?

  • Culturing in shell vials with immunofluorescent antibody (correct)
  • Western blot for viral proteins
  • Mass spectrometry for viral DNA
  • ELISA for viral antibodies

Which statement about CMV retinitis treatment is accurate?

  • Valganciclovir is not effective against CMV retinitis
  • Valganciclovir and Ganciclovir are used for treating CMV retinitis (correct)
  • Cidofovir is used for CMV pneumonia treatment
  • Ganciclovir is not recommended for CMV retinitis in AIDS patients

What is a characteristic feature of CMV inclusion bodies in giant cells?

<p>They are intranuclear and oval with an owl's-eye appearance (D)</p> Signup and view all the answers

In which patient population does CMV commonly cause hepatitis and pneumonitis?

<p>Immunosuppressed patients like transplant recipients (D)</p> Signup and view all the answers

Which method is used to detect CMV nucleic acids in tissues or body fluids?

<p>Polymerase chain reaction (PCR)-based assays (D)</p> Signup and view all the answers

What does CMV Antigenemia measure within blood leukocytes?

<p>pp65 protein using immunofluorescence assay (C)</p> Signup and view all the answers

What treatment is effective against CMV retinitis in AIDS patients?

<p>Valganciclovir (C)</p> Signup and view all the answers

What type of infection can CMV cause in AIDS patients that may lead to blindness?

<p>Retinitis (A)</p> Signup and view all the answers

Which method is used to identify inclusion bodies in CMV infections?

<p>Fluorescent-antibody &amp; histologic staining of inclusion bodies in giant cells (C)</p> Signup and view all the answers

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