Complexation and Protein Binding Quiz
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Questions and Answers

Which of the following is an example of a ligand in complexation?

  • Oxygen
  • Nitrogen
  • Carbon dioxide
  • Water (correct)
  • What is complexation in physical pharmaceutics?

  • The process of breaking down a complex compound into simpler molecules
  • The process of covalent or non-covalent interactions between two or more compounds (correct)
  • The process of forming a single compound from two or more elements
  • The process of separating a compound into its constituent elements
  • What are the altered physical and chemical properties of the complexing species after complexation?

  • Solubility, stability, partition co-efficient, energy absorption, energy emission, conductance (correct)
  • Boiling point, melting point, conductivity, reactivity, molar mass, polarity
  • Viscosity, density, color, odor, taste, pH
  • Surface tension, enthalpy, entropy, pressure, volume, concentration
  • What type of bonds are involved in complex formation?

    <p>Covalent and coordinate covalent</p> Signup and view all the answers

    What is a coordination complex in complexation?

    <p>The product of a Lewis acid-base reaction where ligands bond to a central metal atom by coordinate covalent bonds</p> Signup and view all the answers

    Study Notes

    Complexation in Physical Pharmaceutics

    • A ligand is a molecule or ion that donates one or more electron pairs to a central atom or ion to form a complex.

    Complexation Definition

    • Complexation is a process in which a central atom or ion, typically a metal ion, is bonded to one or more ligands, resulting in a complex species.

    Altered Properties of Complexing Species

    • After complexation, the physical and chemical properties of the complexing species are altered, including changes in solubility, stability, and reactivity.

    Bonds Involved in Complex Formation

    • Coordination bonds, also known as dative covalent bonds, are involved in complex formation, where the ligand donates one or more electron pairs to the central atom or ion.

    Coordination Complex

    • A coordination complex, also known as a complex ion, is a complex species formed by the coordination of one or more ligands to a central atom or ion, resulting in a stable, three-dimensional structure.

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    Description

    Test your knowledge of complexation and protein binding in physical pharmaceutics with this quiz. Explore the process of complex formation and the interactions between drug molecules and ligands.

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