Complexation and Protein Binding Quiz

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Questions and Answers

Which of the following is an example of a ligand in complexation?

  • Oxygen
  • Nitrogen
  • Carbon dioxide
  • Water (correct)

What is complexation in physical pharmaceutics?

  • The process of breaking down a complex compound into simpler molecules
  • The process of covalent or non-covalent interactions between two or more compounds (correct)
  • The process of forming a single compound from two or more elements
  • The process of separating a compound into its constituent elements

What are the altered physical and chemical properties of the complexing species after complexation?

  • Solubility, stability, partition co-efficient, energy absorption, energy emission, conductance (correct)
  • Boiling point, melting point, conductivity, reactivity, molar mass, polarity
  • Viscosity, density, color, odor, taste, pH
  • Surface tension, enthalpy, entropy, pressure, volume, concentration

What type of bonds are involved in complex formation?

<p>Covalent and coordinate covalent (C)</p> Signup and view all the answers

What is a coordination complex in complexation?

<p>The product of a Lewis acid-base reaction where ligands bond to a central metal atom by coordinate covalent bonds (B)</p> Signup and view all the answers

Flashcards

Ligand in complexation

A molecule or ion that bonds to a central metal atom in a complex.

Complexation definition

The process of forming complexes through interactions between two or more compounds.

Complex properties change

Changes in solubility, stability, partitioning, energy, and conductance occur when compounds complex.

Complex formation bonds

Involves covalent and coordinate covalent bonds.

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Coordination complex

A complex where ligands bond to a central metal by coordinate covalent bonding.

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Study Notes

Complexation in Physical Pharmaceutics

  • A ligand is a molecule or ion that donates one or more electron pairs to a central atom or ion to form a complex.

Complexation Definition

  • Complexation is a process in which a central atom or ion, typically a metal ion, is bonded to one or more ligands, resulting in a complex species.

Altered Properties of Complexing Species

  • After complexation, the physical and chemical properties of the complexing species are altered, including changes in solubility, stability, and reactivity.

Bonds Involved in Complex Formation

  • Coordination bonds, also known as dative covalent bonds, are involved in complex formation, where the ligand donates one or more electron pairs to the central atom or ion.

Coordination Complex

  • A coordination complex, also known as a complex ion, is a complex species formed by the coordination of one or more ligands to a central atom or ion, resulting in a stable, three-dimensional structure.

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