Podcast
Questions and Answers
Which cell types are involved in classical macrophage activation?
Which cell types are involved in classical macrophage activation?
- Neutrophils and Monocytes (correct)
- Mast Cells
- Monocytes/Macrophages
- Dendritic Cells
What induces alternative macrophage activation?
What induces alternative macrophage activation?
- TLRs
- Histamine
- IL-4 and IL-13 (correct)
- IFN-γ
Which cells serve as sentinels in tissues and play a role in initiating inflammation?
Which cells serve as sentinels in tissues and play a role in initiating inflammation?
- Mast Cells
- Dendritic Cells (correct)
- Monocytes/Macrophages
- Neutrophils
What are the main functions of dendritic cells in the immune system?
What are the main functions of dendritic cells in the immune system?
Mast cells are activated by which of the following mechanisms?
Mast cells are activated by which of the following mechanisms?
What do mast cells release when activated?
What do mast cells release when activated?
What is the primary function of antimicrobial peptides Defensins and cathelicidins?
What is the primary function of antimicrobial peptides Defensins and cathelicidins?
Which of the following is a function of epithelia in innate immunity?
Which of the following is a function of epithelia in innate immunity?
What is a unique feature of Intraepithelial T Lymphocytes' antigen receptors?
What is a unique feature of Intraepithelial T Lymphocytes' antigen receptors?
Why are Neutrophils considered as early responders in the immune system?
Why are Neutrophils considered as early responders in the immune system?
Which type of phagocyte survives in tissues for long periods?
Which type of phagocyte survives in tissues for long periods?
What do Phagocytes like Monocytes/Macrophages do to microbes at sites of infection?
What do Phagocytes like Monocytes/Macrophages do to microbes at sites of infection?
What is the main characteristic that activates Natural Killer (NK) cells?
What is the main characteristic that activates Natural Killer (NK) cells?
Which pathway of the complement system is activated by mannose-binding lectin (MBL) binding to carbohydrate ligands on microbes?
Which pathway of the complement system is activated by mannose-binding lectin (MBL) binding to carbohydrate ligands on microbes?
What happens to the inhibitory receptors of NK cells when class I MHC expression is reduced on infected cells?
What happens to the inhibitory receptors of NK cells when class I MHC expression is reduced on infected cells?
Which pathway of the complement system is triggered by antibodies binding to microbes?
Which pathway of the complement system is triggered by antibodies binding to microbes?
Why is the alternative pathway of the complement system not controlled on microbial surfaces?
Why is the alternative pathway of the complement system not controlled on microbial surfaces?
Which component of the immune system do complement proteins belong to?
Which component of the immune system do complement proteins belong to?
What is the role of C-reactive protein (CRP) in innate immunity?
What is the role of C-reactive protein (CRP) in innate immunity?
Which cells are the principal sources of cytokines in innate immunity?
Which cells are the principal sources of cytokines in innate immunity?
What are the principal cytokines involved in recruiting blood neutrophils and monocytes to sites of infection?
What are the principal cytokines involved in recruiting blood neutrophils and monocytes to sites of infection?
What do cytokines do in immune and inflammatory reactions?
What do cytokines do in immune and inflammatory reactions?
What is the main effect of TNF and IL-1 in innate immunity?
What is the main effect of TNF and IL-1 in innate immunity?
What is the central component of all complement pathways?
What is the central component of all complement pathways?
Which complement protein is responsible for recruiting and activating downstream complement proteins on the microbial surface?
Which complement protein is responsible for recruiting and activating downstream complement proteins on the microbial surface?
What function does C5a mainly serve in the complement system?
What function does C5a mainly serve in the complement system?
Which plasma protein in innate immunity recognizes microbial carbohydrates?
Which plasma protein in innate immunity recognizes microbial carbohydrates?
What is the function of surfactant proteins in the lungs with respect to innate immunity?
What is the function of surfactant proteins in the lungs with respect to innate immunity?
What is the main consequence of the formation of the membrane attack complex (MAC) on a microbe?
What is the main consequence of the formation of the membrane attack complex (MAC) on a microbe?
