Podcast
Questions and Answers
What is the main function of opsonization of microbes by Complement components?
What is the main function of opsonization of microbes by Complement components?
- Inducing inflammation
- Increasing vascular permeability
- Coactivating B cells
- Inducing phagocytosis (correct)
Which complement component is responsible for increasing extravasation of plasma proteins and monocytes/neutrophils?
Which complement component is responsible for increasing extravasation of plasma proteins and monocytes/neutrophils?
- C3a
- Factor I
- C4a
- C5a (correct)
What is the role of Factor H in the regulation of Complement?
What is the role of Factor H in the regulation of Complement?
- Binds to C3b and helps Factor I cleave C3b (correct)
- Binds to C3b or C4b and disassociates C3 convertase
- Dissociates C1s and C1r from C1q
- Binds to CR2 on B cells
Which pathway of the complement system involves triggering events that lead to the same terminal pathway?
Which pathway of the complement system involves triggering events that lead to the same terminal pathway?
What is the complement component that binds to an antigen-antibody complex in the classical pathway?
What is the complement component that binds to an antigen-antibody complex in the classical pathway?
Which complement proteins can fix complement proteins in the classical pathway?
Which complement proteins can fix complement proteins in the classical pathway?
In the lectin pathway, what molecule binds to mannan present on the surface of microbes?
In the lectin pathway, what molecule binds to mannan present on the surface of microbes?
What is the function of mast cells and basophils?
What is the function of mast cells and basophils?
How are natural killer (NK) cells activated?
How are natural killer (NK) cells activated?
What is the role of inhibitory receptors in NK cell activation?
What is the role of inhibitory receptors in NK cell activation?
What do neutrophils primarily mediate in the inflammatory response?
What do neutrophils primarily mediate in the inflammatory response?
Which antibody is designed to protect from helminth but is remembered for allergic reactions?
Which antibody is designed to protect from helminth but is remembered for allergic reactions?
Which antibody is the largest and the first antibody produced?
Which antibody is the largest and the first antibody produced?
Which antibody is most commonly found in blood and other body fluids?
Which antibody is most commonly found in blood and other body fluids?
Which antibody is a marker used to define mature B cells?
Which antibody is a marker used to define mature B cells?
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