10 Questions
What is the primary cause of damage to myelin or axons in Guillain-Barre Syndrome?
Direct attack by the immune system on Schwann cells
Which area of the nerve is primarily affected in Guillain-Barre Syndrome?
Nodes of Ranvier
What is one of the potential outcomes of axonal damage and degeneration in Guillain-Barre Syndrome?
Slowed conduction velocity
What is the typical sequence of conduction block presentation in Guillain-Barre Syndrome?
Partial block initially, then complete conduction block by 4 weeks
What is the most common nerve affected in Guillain-Barre Syndrome?
Peroneal nerve
What is the suspected cause of Guillain-Barre Syndrome based on current understanding?
Autoimmune response to infection
Which component of the immune system plays a significant role in causing damage in Guillain-Barre Syndrome?
Complement system molecules and actions
What is the potential consequence of a complete conduction block in Guillain-Barre Syndrome?
'Dead areas' in muscle responsiveness
What characterizes the initial presentation of conduction velocity in Guillain-Barre Syndrome?
Partial block followed by complete conduction block
Which part of the nervous system is primarily targeted by the immune response in Guillain-Barre Syndrome?
Peripheral nerves including myelin and axons
Test your knowledge on the cascade of events in the complement system that leads to damage to myelin and axons in the nervous system. Learn about how inflammation exacerbates this damage and the potential for resulting axonal degeneration.
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