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Questions and Answers
Which pathway of complement activation is initiated by microbes in the absence of antibody?
Which pathway of complement activation is initiated by microbes in the absence of antibody?
- Classical pathway
- Alternative pathway (correct)
- Lectin pathway
- All three pathways
Which complement protein plays a central role in all three pathways of complement activation?
Which complement protein plays a central role in all three pathways of complement activation?
- Factor D
- C3 (correct)
- Factor B
- C2
What stabilizes the alternative pathway C3 convertase?
What stabilizes the alternative pathway C3 convertase?
- C3b
- Properdin (correct)
- Factor B
- Factor D
Which pathway of complement activation is triggered by the binding of IgM or certain subclasses of IgG to antigens?
Which pathway of complement activation is triggered by the binding of IgM or certain subclasses of IgG to antigens?
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What is the name of the complex formed by the binding and sequential cleavage of C4 and C2 in the classical pathway?
What is the name of the complex formed by the binding and sequential cleavage of C4 and C2 in the classical pathway?
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Which pathway of complement activation is initiated by the attachment of plasma mannose-binding lectin (MBL) to microbes?
Which pathway of complement activation is initiated by the attachment of plasma mannose-binding lectin (MBL) to microbes?
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What is the name of the complex formed by the binding of C5 to the C5 convertase and subsequent proteolysis of C5?
What is the name of the complex formed by the binding of C5 to the C5 convertase and subsequent proteolysis of C5?
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