14 Questions
What is the effect of ezetimibe on LDL-C levels when added to diet?
Decrease by 15-20%
In patients with primary hypercholesterolemia where initial statin therapy is contraindicated, what is the recommended treatment?
Ezetimibe monotherapy
What is the recommended daily dosage of ezetimibe?
10 mg
Which group of drugs is thought to act by binding to peroxisome proliferator-activated receptor α on hepatocytes?
Fibrates
What effect does ezetimibe have when added to a statin therapy?
Lowers LDL-C by approximately 20%
In which patients is ezetimibe contraindicated when co-administered with a statin?
Patients with active liver disease
What is the maximum daily dose for Lomitapide?
60 mg
Which of the following conditions is a contraindication for Lomitapide use?
Inflammatory bowel disease
What adverse event is mainly associated with the use of Lomitapide?
Diarrhea
For which condition should Lomitapide be used according to the text?
Homozygous familial hypercholesterolemia
What enzyme does Lomitapide inhibit?
Microsomal triglyceride transfer protein
What is a possible effect of Lomitapide treatment on liver function tests according to the text?
Increased alanine transaminase levels
What is the main purpose of lipoprotein apheresis treatment?
To remove LDL-C, Lp(a), and triglycerides from the plasma.
Why is the effect of lipoprotein apheresis considered transient?
Because it only temporarily lowers LDL-C.
Learn about the common side effects experienced by patients taking certain drugs, as well as the use of lipoprotein apheresis in treating severe treatment-resistant hypercholesterolemia. Explore the impact of lipoprotein apheresis in removing LDL-C and Lp(a) from the body.
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