Podcast
Questions and Answers
What is the normal range for Aspartate aminotransferase (AST)?
What is the normal range for Aspartate aminotransferase (AST)?
Which of the following tests measures cholestasis?
Which of the following tests measures cholestasis?
Which laboratory value primarily assesses kidney function?
Which laboratory value primarily assesses kidney function?
What implication does a 30% reduction in GFR have in elderly patients?
What implication does a 30% reduction in GFR have in elderly patients?
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Which of these is a measure of hepatocellular damage?
Which of these is a measure of hepatocellular damage?
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Study Notes
Common Laboratory Values Overview
- Laboratory tests help evaluate organ function and detect diseases.
- Normal ranges for key tests typically indicate healthy organ function.
Aspartate Aminotransferase (AST)
- Range: 0-40 units/L
- Indicates hepatocellular damage.
- Elevated levels may occur in:
- Valproate therapy
- Hepatitis
- Cirrhosis
- Levels may decrease in chronic alcoholic liver disease.
Alanine Aminotransferase (ALT)
- Range: 0-40 units/L
- Reflects hepatocellular damage similar to AST.
- Elevated levels can arise from:
- Valproate therapy
- Hepatitis
- Cirrhosis
- May also decrease in chronic alcoholic liver disease.
Gamma-Glutamyl Transferase (GGT)
- Range: 0-30 units/L
- Measures cholestasis, related to bile flow issues either extrahepatic or intrahepatic.
- Elevated levels often indicate:
- Alcohol abuse
- Chronic alcoholic liver disease.
Alkaline Phosphatase (ALP)
- Range: 30-120 international units/L
- Assesses cholestasis and bile flow disruptions.
- Elevated levels can indicate:
- Gallbladder disease
- Liver disease
- Bone injury or rapid bone growth.
Creatine Kinase (CK)
- Normal range: >90 mL/min/1.73m²
- Best indicator of kidney function.
- Elderly may have decreased GFR (30% reduction) despite normal creatinine levels due to reduced muscle mass.
- No dosage adjustment or contraindications for most psychotropics when GFR >60 mL/min/1.73m².
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Description
Test your knowledge on important laboratory values with this quiz. You'll explore the significance of various tests like AST and ALT, their normal ranges, and what elevated or decreased values might indicate in clinical contexts.
