Common Laboratory Values Quiz

Common Laboratory Values Overview

• Laboratory tests help evaluate organ function and detect diseases.
• Normal ranges for key tests typically indicate healthy organ function.

Aspartate Aminotransferase (AST)

• Range: 0-40 units/L
• Indicates hepatocellular damage.
• Elevated levels may occur in:
  • Valproate therapy
  • Hepatitis
  • Cirrhosis
• Levels may decrease in chronic alcoholic liver disease.

Alanine Aminotransferase (ALT)

• Range: 0-40 units/L
• Reflects hepatocellular damage similar to AST.
• Elevated levels can arise from:
  • Valproate therapy
  • Hepatitis
  • Cirrhosis
• May also decrease in chronic alcoholic liver disease.

Gamma-Glutamyl Transferase (GGT)

• Range: 0-30 units/L
• Measures cholestasis, related to bile flow issues either extrahepatic or intrahepatic.
• Elevated levels often indicate:
  • Alcohol abuse
  • Chronic alcoholic liver disease.

Alkaline Phosphatase (ALP)

• Range: 30-120 international units/L
• Assesses cholestasis and bile flow disruptions.
• Elevated levels can indicate:
  • Gallbladder disease
  • Liver disease
  • Bone injury or rapid bone growth.

Creatine Kinase (CK)

• Normal range: >90 mL/min/1.73m²
• Best indicator of kidney function.
• Elderly may have decreased GFR (30% reduction) despite normal creatinine levels due to reduced muscle mass.
• No dosage adjustment or contraindications for most psychotropics when GFR >60 mL/min/1.73m².