HTN Medications

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Questions and Answers

Which of the following is a common side effect of loop diuretics such as furosemide (Lasix)?

  • Constipation
  • Hyperkalemia
  • Hypokalemia (correct)
  • Bradycardia

Which medication works by blocking beta-adrenergic receptors, leading to decreased heart rate and cardiac output?

  • Lisinopril
  • Metoprolol (correct)
  • Terazosin
  • Amlodipine

A patient taking lisinopril develops a persistent dry cough. What is the most likely cause of this symptom?

  • Elevated potassium
  • Accumulation of kinins (correct)
  • Increased cardiac workload
  • Bronchospasm

Which of the following medications may cause reflex tachycardia and should be used cautiously with beta-blockers or digoxin?

<p>Amlodipine (C)</p> Signup and view all the answers

What is the primary action of ARBs like losartan?

<p>Block angiotensin II receptors (B)</p> Signup and view all the answers

A nurse should monitor which of the following when administering hydrochlorothiazide? (Select All That Apply)

<p>Signs of dehydration (A), Blood glucose (C), Serum calcium (D), Potassium levels (E)</p> Signup and view all the answers

A patient with asthma is prescribed enalapril. What is the nurse's primary concern?

<p>Worsening bronchospasm (A)</p> Signup and view all the answers

Which of the following is a side effect of calcium channel blockers like diltiazem? (Select All That Apply)

<p>Heart block (A), Reflex tachycardia (B), Constipation (E)</p> Signup and view all the answers

What is the mechanism of action of terazosin?

<p>Blocks alpha receptors in smooth muscle (D)</p> Signup and view all the answers

Which of the following should the nurse teach a patient taking furosemide?

<p>Report muscle weakness or cramping (B)</p> Signup and view all the answers

ACE inhibitors and ARBs both ultimately act to:

<p>Decrease vasoconstriction (C)</p> Signup and view all the answers

Which patient would most benefit from beta-blocker therapy for hypertension?

<p>Patient with a history of MI (B)</p> Signup and view all the answers

Which medication class would be contraindicated in a patient with second-degree AV block?

<p>Calcium channel blockers (D)</p> Signup and view all the answers

When administering ARBs like valsartan, the nurse should monitor for: (Select All That Apply)

<p>Hyperkalemia (B), Hypotension (C), Dizziness (D), Angioedema (E)</p> Signup and view all the answers

Which of the following medications can cause palpitations as a side effect?

<p>Terazosin (B)</p> Signup and view all the answers

Why should potassium be included in the diet of patients on loop diuretics?

<p>To avoid muscle cramps and arrhythmias (D)</p> Signup and view all the answers

A nurse is teaching a patient starting amlodipine. Which statement indicates a need for further teaching?

<p>&quot;This drug will raise my heart rate permanently.&quot; (A)</p> Signup and view all the answers

Which of the following statements about ACE inhibitors is true?

<p>They prevent the conversion of angiotensin I to angiotensin II (A)</p> Signup and view all the answers

A patient taking ARBs reports feeling lightheaded when standing. What condition is likely?

<p>Orthostatic hypotension (B)</p> Signup and view all the answers

A nurse should question a prescription for diltiazem in which patient?

<p>AV block (D)</p> Signup and view all the answers

The nurse knows that beta-blockers: (Select All That Apply)

<p>Block sympathetic stimulation (C), Decrease heart rate (D), Are beneficial in heart failure patients (E)</p> Signup and view all the answers

Which of the following is an important teaching point for a patient starting terazosin?

<p>Rise slowly to prevent dizziness (D)</p> Signup and view all the answers

Which of the following drugs should be used cautiously in patients with renal impairment?

<p>Lisinopril (A)</p> Signup and view all the answers

The nurse explains that amlodipine works by:

<p>Inhibiting calcium influx into smooth muscle (A)</p> Signup and view all the answers

A patient on hydrochlorothiazide reports leg cramps and weakness. What is the nurse's priority?

<p>Check potassium levels (C)</p> Signup and view all the answers

Flashcards

Loop Diuretics Side Effect

Loop diuretics increase potassium excretion, increasing the risk of hypokalemia.

Metoprolol Action

Metoprolol decreases sympathetic stimulation to the heart, thus lowering blood pressure.

Lisinopril & Dry Cough

ACE inhibitors may increase bradykinin levels, leading to a chronic cough.

Amlodipine and Reflex Tachycardia

Amlodipine is a calcium channel blocker that may cause reflex tachycardia.

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ARBs Mechanism

ARBs prevent angiotensin II from binding to receptors, resulting in vasodilation.

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Hydrochlorothiazide Monitoring

Thiazide diuretics can cause hypokalemia, hyperglycemia, dehydration, and increased calcium.

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Enalapril and Asthma

ACE inhibitors can cause cough or bronchospasm due to increased kinins; caution in asthmatics.

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Diltiazem Side Effects

CCBs can cause constipation, exacerbate heart blocks, and lead to reflex tachycardia.

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Terazosin Mechanism

Alpha-blockers like terazosin promote vasodilation by reducing vasomotor tone.

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Furosemide Teaching

Muscle weakness or cramping are signs of hypokalemia, a known risk of loop diuretics.

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ACE Inhibitors and ARBs

Both drug classes decrease the effects of angiotensin II, promoting vasodilation.

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Beta-Blockers and MI

Beta-blockers reduce cardiac workload and are cardioprotective post-MI.

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CCBs and AV Block

CCBs can worsen heart blocks due to effects on conduction.

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ARBs Adverse Effects

ARBs may cause hypotension, dizziness, hyperkalemia, and rarely angioedema (like ACE inhibitors).

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Terazosin Side Effect

Alpha-blockers can lead to reflex tachycardia and palpitations.

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Potassium and Loop Diuretics

Loop diuretics can cause hypokalemia, leading to cramps and dysrhythmias.

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Amlodipine Teaching

Reflex tachycardia may occur but is not a permanent effect.

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ACE Inhibitors Mechanism

They prevent the conversion of angiotensin I to angiotensin II

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ARBs and Lightheadedness

ARBs can lower blood pressure enough to cause postural hypotension.

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Diltiazem Contraindication

Diltiazem can worsen AV conduction issues.

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Study Notes

Loop Diuretics (e.g., Furosemide/Lasix)

  • Hypokalemia is a common side effect because they increase potassium excretion

Beta-Adrenergic Receptor Blockers (e.g., Metoprolol)

  • Decrease heart rate and cardiac output through reducing sympathetic stimulation to the heart

ACE Inhibitors (e.g., Lisinopril)

  • A persistent dry cough can occur due to an increase in bradykinin levels

Calcium Channel Blockers (e.g., Amlodipine)

  • Can cause reflex tachycardia, so use cautiously with beta-blockers or digoxin

Angiotensin II Receptor Blockers (ARBs, e.g., Losartan)

  • Primary action is to prevent angiotensin II from binding to receptors, causing vasodilation

Hydrochlorothiazide Monitoring

  • Monitor potassium levels, blood glucose, signs of dehydration, and serum calcium
  • Thiazide diuretics can cause hypokalemia, hyperglycemia, dehydration, and increased calcium

Enalapril Considerations for Asthmatic Patients

  • Worsening bronchospasm is a primary concern because ACE inhibitors can cause cough or bronchospasm due to increased kinins

Calcium Channel Blockers (e.g., Diltiazem) Side Effects

  • Side effects include constipation, heart block, and reflex tachycardia

Terazosin Mechanism of Action

  • Promotes vasodilation by reducing vasomotor tone

Furosemide (Loop Diuretic) Patient Education

  • Report muscle weakness or cramping as it indicates hypokalemia, a known risk

ACE Inhibitors and ARBs Shared Action

  • Both drug classes decrease the effects of angiotensin II, leading to vasodilation and decreased vasoconstriction

Beta-Blocker Benefits for Hypertension

  • Most beneficial for patients with a history of myocardial infarction because they reduce cardiac workload and are cardioprotective

Contraindication for Calcium Channel Blockers

  • Contraindicated in patients with second-degree AV block as they can worsen heart blocks due to effects on conduction

ARB Monitoring (e.g., Valsartan)

  • Monitor for hypotension, dizziness, hyperkalemia, and angioedema

Terazosin Side Effects

  • Can lead to reflex tachycardia and palpitations

Potassium Supplementation with Loop Diuretics

  • Needed to avoid muscle cramps and arrhythmias, which can result from hypokalemia

Amlodipine Patient Teaching

  • Reflex tachycardia is not a permanent effect

ACE Inhibitors Mechanism

  • Prevent the conversion of angiotensin I to angiotensin II

Lightheadedness with ARBs

  • Likely orthostatic hypotension because ARBs can lower blood pressure

Diltiazem Contraindications

  • Should not be prescribed to patients with AV block because it can worsen AV conduction issues

Beta-Blocker Effects

  • Slow heart rate, reduce sympathetic activity, and help in heart failure by lowering workload

Terazosin Patient Education

  • Rise slowly to prevent dizziness, as alpha-blockers can cause orthostatic hypotension

Lisinopril Caution in Renal Impairment

  • Exercise caution using lisinopril with renal impairment as ACE inhibitors can worsen renal function, especially in those with bilateral renal artery stenosis

Amlodipine Mechanism

  • Inhibits calcium influx into smooth muscle, causing vasodilation and decreased blood pressure

Hydrochlorothiazide Side Effects

  • Leg cramps and weakness indicate hypokalemia, a common side effect, so check potassium levels

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