Combination Therapies in PCOS Treatment
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Questions and Answers

Which lifestyle interventions are considered the most effective therapeutic approaches for PCOS treatment?

  • Medication management and hormonal treatments
  • Exercise and weight reduction (correct)
  • Surgery and herbal therapies
  • Acupuncture and aromatherapy
  • Why is Spironolactone used in cases where some women cannot tolerate other medicines?

  • Due to its high cost
  • Its effectiveness in reducing hirsuteness (correct)
  • To increase insulin sensitivity
  • Because it is an oral contraceptive
  • What is a reason why Cyproterone is not recommended for patients without reliable contraception?

  • It is a hormonal treatment
  • It has a similar effect on reducing hirsuteness to finasteride (correct)
  • It is an oral contraceptive
  • It is affordable
  • Which type of treatments have shown promising results in studies related to PCOS pathophysiology?

    <p>Insulin sensitizing and anti-androgenic treatments</p> Signup and view all the answers

    What was the outcome of the study on combined rosiglitazone and flutamide treatment for PCOS?

    <p>No further benefit compared to using either drug alone</p> Signup and view all the answers

    Why are androgen lowering agents for PCOS considered off-label medications?

    <p>They have not been approved by the US FDA for this specific use</p> Signup and view all the answers

    What is the primary reason oral contraceptives are often considered first-line therapy for women with PCOS?

    <p>To protect the endometrium from hyperplasia</p> Signup and view all the answers

    What effect have statins been investigated for in relation to PCOS?

    <p>Decreasing hirsutism scores</p> Signup and view all the answers

    Which medication has shown a 30% reduction in hirsutism scores but is not widely used due to teratogenicity concerns?

    <p>Finasteride</p> Signup and view all the answers

    Which group of medications has been shown to have positive effects on PCOS but only in patients with abnormal glucose metabolism?

    <p>Insulin sensitizers</p> Signup and view all the answers

    What is the key factor in PCOS that contributes to increased androgen secretion from the ovaries?

    <p>High insulin levels and reduced sex hormone binding globulin production in the liver</p> Signup and view all the answers

    How do oral contraceptives alleviate symptoms of PCOS like acne and hirsutism?

    <p>By reducing free androgens</p> Signup and view all the answers

    What is the primary benefit of combining metformin with oral contraceptives for PCOS treatment?

    <p>To improve menstrual regulation and alleviate hirsutism</p> Signup and view all the answers

    How does metformin benefit PCOS patients who are unable to induce ovulation alone?

    <p>By improving granulosa cell function and correcting abnormalities</p> Signup and view all the answers

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