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What is the main factor that affects the diffusion of small ions through a membrane?
What is the main factor that affects the diffusion of small ions through a membrane?
- Shape of the macromolecule
- Charge of the macromolecule (correct)
- Size of the macromolecule
- Solubility of the macromolecule
What is the purpose of co-administering a macromolecule with an ionizable drug in the GIT?
What is the purpose of co-administering a macromolecule with an ionizable drug in the GIT?
- To facilitate the absorption of the drug (correct)
- To slow down the diffusion of the drug
- To neutralize the charge of the drug
- To enhance the solubility of the drug
What type of macromolecule is co-administered with potassium benzyl penicillin to enhance its diffusion?
What type of macromolecule is co-administered with potassium benzyl penicillin to enhance its diffusion?
- Neutral macromolecule
- Zwitterionic macromolecule
- Cationic macromolecule
- Anionic macromolecule (correct)
What is the underlying mechanism that facilitates the diffusion of an ionizable drug in the presence of a macromolecule?
What is the underlying mechanism that facilitates the diffusion of an ionizable drug in the presence of a macromolecule?
What is the term that describes the effect of a charged macromolecule on the diffusion of small ions through a membrane?
What is the term that describes the effect of a charged macromolecule on the diffusion of small ions through a membrane?
What is the location where the co-administration of a macromolecule with an ionizable drug is applied?
What is the location where the co-administration of a macromolecule with an ionizable drug is applied?
What is the role of the macromolecule in the Donnan membrane effect?
What is the role of the macromolecule in the Donnan membrane effect?
What is the characteristic of the macromolecule that affects the diffusion of small ions through a membrane?
What is the characteristic of the macromolecule that affects the diffusion of small ions through a membrane?
What is the outcome of the co-administration of a macromolecule with an ionizable drug in the GIT?
What is the outcome of the co-administration of a macromolecule with an ionizable drug in the GIT?
What is the electrical property that is related to the Donnan membrane effect?
What is the electrical property that is related to the Donnan membrane effect?
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