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Colloidal Dispersions and Light Scattering

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Colloidal Dispersions and Light Scattering

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Questions and Answers

What is the main factor that affects the diffusion of small ions through a membrane?

Shape of the macromolecule

Charge of the macromolecule (correct)

Size of the macromolecule

Solubility of the macromolecule

What is the purpose of co-administering a macromolecule with an ionizable drug in the GIT?

To facilitate the absorption of the drug (correct)

To slow down the diffusion of the drug

To neutralize the charge of the drug

To enhance the solubility of the drug

What type of macromolecule is co-administered with potassium benzyl penicillin to enhance its diffusion?

Neutral macromolecule

Zwitterionic macromolecule

Cationic macromolecule

Anionic macromolecule (correct)

What is the underlying mechanism that facilitates the diffusion of an ionizable drug in the presence of a macromolecule?

Mutual ionic repulsion Signup and view all the answers

What is the term that describes the effect of a charged macromolecule on the diffusion of small ions through a membrane?

Donnan membrane effect Signup and view all the answers

What is the location where the co-administration of a macromolecule with an ionizable drug is applied?

Gastrointestinal tract (GIT) Signup and view all the answers

What is the role of the macromolecule in the Donnan membrane effect?

To facilitate the diffusion of ions Signup and view all the answers

What is the characteristic of the macromolecule that affects the diffusion of small ions through a membrane?

Charge Signup and view all the answers

What is the outcome of the co-administration of a macromolecule with an ionizable drug in the GIT?

Enhanced absorption of the drug Signup and view all the answers

What is the electrical property that is related to the Donnan membrane effect?

Electrical double layer Signup and view all the answers